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1 Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance.
article 2005    
Author: Cnubben, N.H. · Wortelboer, H.M. · Zanden, J.J. van · Rietjens, I.M. · Bladeren, P.J. van
Keywords: Health Pharmacology · Physiological Sciences · ABC transporter · cyclosporin derivative · dibenzo[a,d]cycloheptene derivative · glycoprotein P · quinoline derivative · valspodar · zosuquidar · drug antagonism · drug design · drug effect · genetics · human · metabolism · multidrug resistance · review · RNA interference · transport at the cellular level · ATP-Binding Cassette Transporters · Biological Transport · Cyclosporins · Dibenzocycloheptenes · Drug Design · Drug Resistance, Multiple · Humans · P-Glycoproteins · Quinolines · RNA Interference
[Abstract]

2 Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: Comparison of active and passive transport with the human colon carcinoma Caco-2 cell line
article 2002    
Author: Versantvoort, C.H.M. · Ondrewater, R.C.A. · Duizer, E. · Sandt, J.J.M. van de · Gilde, A.J. · Groten, J.P.
Keywords: Caco-2 · Carrier-mediated transport · H+-di/tripeptide carrier · IEC-18 · Intestinal cell lines · MRP · P-Glycoprotein · acetylsalicylic acid · calcein · carrier protein · dinitrophenylglutathione · glucose derivative · glutathione derivative · glycoprotein P · glycylsarcosine · hydrocortisone · macrogol 4000 · mannitol · methylglucose · multidrug resistance protein · probenecid · propranolol · rhodamine 123 · salicylic acid · testosterone · unclassified drug · verapamil · vincristine · animal cell · article · cell membrane permeability · cell strain CACO 2 · cell transport · colon carcinoma · controlled study · drug transport · human · human cell · in vitro study · ion transport · model · nonhuman · priority journal · protein expression · rat · screening
[Abstract]

3 Myricetin stimulates the absorption of the pro-carcinogen PhIP
article 2006    
Author: Schutte, M.E. · Sandt, J.J.M. van de · Alink, G.M. · Groten, J.P. · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · ABC transporter · Apparent permeability · Caco-2 · Myricetin · PhIP · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · carcinogen · cyclosporin A · glycoprotein P inhibitor · multidrug resistance protein 2 · myricetin · valspodar · absorption · article · cell differentiation · cell strain CACO 2 · cell transport · concentration (parameters) · excretion · human · human cell · intestine epithelium cell · priority journal · stimulation · Absorption · ATP-Binding Cassette Transporters · Caco-2 Cells · Carcinogens · Flavonoids · Humans · Imidazoles · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Permeability
[Abstract]

4 Role of glutathione, glutathione S-transferases and multidrug resistance-related proteins in cisplatin sensitivity of head and neck cancer cell lines
article 1998    
Author: Welters, M.J.P. · Fichtinger-Schepman, A.M.J. · Baan, R.A. · Flens, M.J. · Scheper, R.J. · Braakhuis, B.J.M.
Keywords: Nutrition · Cisplatin · Glutathione · Glutathione S-transferase · Head and neck cancer · Multidrug resistance · Calcein · Glycoprotein p · Multidrug resistance protein · Cancer cell culture · Controlled study · Drug sensitivity · Drug transport · Head and neck cancer · Human cell · Immunocytochemistry · Membrane transport · Antineoplastic Agents · ATP-Binding Cassette Transporters · Drug Resistance, Multiple · Drug Resistance, Neoplasm · Enzyme Inducti · Glutathione Transferase · Head and Neck Neoplasms · Humans · Multidrug Resistance-Associated Proteins · Neoplasm Proteins · P-Glycoprotein · Vault Ribonucleoprotein Particles
[PDF] [Abstract]

5 Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes
article 2009    
Author: Treijtel, N. · Eijkeren, J.C.H.v. · Nijmeijer, S. · Greef de - Sandt, I.C.J. van der · Freidig, A.P.
Keywords: Health · Biomedical Research · HIV-protease inhibitors · Metabolism · P-Glycoprotein · Rat hepatocytes · rat liver microsomes · Sandwich-culture · cyclosporin A · drug metabolite · glycoprotein P · ketoconazole · proteinase inhibitor · ritonavir · saquinavir · testosterone derivative · valspodar · verapamil · animal cell · article · cell culture · controlled study · drug clearance · drug excretion · drug metabolism · drug transport · Human immunodeficiency virus 1 · hydroxylation · intrahepatic bile duct · liver cell · liver metabolism · male · microsome · nonhuman · rat · sandwich culture · Animals · Biological Transport, Active · Cell Culture Techniques · Cell Survival · Cells, Cultured · Cyclosporine · Cyclosporins · Dose-Response Relationship, Drug · Hepatocytes · HIV Protease Inhibitors · Ketoconazole · Male · Metabolic Clearance Rate · Microsomes, Liver · Rats · Rats, Wistar · Ritonavir · Saquinavir · Human immunodeficiency virus 1 · Rattus
[Abstract]

6 P-glycoprotein-deficient mice have proximal tubule dysfunction but are protected against ischemic renal injury
article 2007    
Author: Huls, M. · Kramers, C. · Levtchenko, E.N. · Wilmer, M.J.G. · Dijkman, H.B.P.M. · Kluijtmans, L.A.J. · Hoorn, J.W.A. van der · Russel, F.G.M. · Masereeuw, R.
Keywords: Biology · ABC transporter · Drug transporter · Ischemia-reperfusion · Kidney dysfunction · ABC transporter · adenosine triphosphate · amino acid · calcium · creatinine · glucose · glycoprotein P · lithium · protein · sodium · amino acid urine level · animal model · animal tissue · calcium excretion · controlled study · creatinine clearance · diuresis · electron microscopy · glomerulus filtration rate · glucosuria · kidney blood flow · kidney cortex · kidney injury · kidney ischemia · kidney proximal tubule · kidney tubule necrosis · knockout mouse · oxidative stress · plasma clearance · priority journal · protein expression · protein function · sodium excretion · upregulation · urinary excretion · Amino Acids · Animals · Calcium · Diuresis · Fluorescent Antibody Technique · Glomerular Filtration Rate · Glycosuria · Immunohistochemistry · Ischemia · Kidney Failure, Acute · Kidney Tubules, Proximal · Male · Mice · Mice, Inbred Strains · Mice, Knockout · Mitochondria · P-Glycoprotein · Proteinuria · Renal Circulation · Sodium
[Abstract]

7 Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice
article 2005    
Author: Hulzebos, C.V. · Voshol, P.J. · Wolters, H. · Kruit, J.K. · Ottenhof, R. · Groen, A.K. · Stellaard, F. · Verkade, H.J. · Kuipers, F.
Keywords: Bile flow · Bile formation · Bile salt synthesis · Cholangiocyte · Cholate kinetics · Cholehepatic shunt · beta actin · bile salt · binding protein · carrier protein · chenodeoxycholic acid · cholic acid · deoxycholic acid · glycoprotein P · ileal bile salt binding protein · lithocholic acid · messenger RNA · multidrug resistance protein 2 · multidrug resistance protein 3 · muricholic acid · tauroursodeoxycholic acid · unclassified drug · animal experiment · animal model · animal tissue · bile acid synthesis · cell proliferation · controlled study · dilution · immunohistochemistry · in vivo study · intestine mucosa · intrahepatic bile duct · kinetics · liver parenchyma · male · mouse · nonhuman · nucleotide sequence · protein analysis · protein deficiency · protein expression · upregulation · Western blotting · wild type · Animals · Bile Acids and Salts · Bile Duct Diseases · Bile Ducts · Carrier Proteins · Cell Division · Cholates · Deuterium · Gallbladder · Intestines · Membrane Glycoproteins · Mice · Mice, Mutant Strains · Organic Anion Transporters, Sodium-Dependent · P-Glycoproteins · Phospholipids · RNA, Messenger · Symporters
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date