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Showing 1 to 17 of 17 found. | Sort by date

1 The ultimate radiochemical nightmare : upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule
article 2015    
Author: Uhm, J.I.M. van · Visser, G.W.M. · Schans, M.J. van der · Geldof, A.A. · Meuleman, E.J.H. · Nieuwenhuijzen, J.A.
Keywords: Botulinum neurotoxin A · Iodine-125 · Monoclonal antibody · PET research · Radio-iodination · Botulinum toxin A · Cetuximab · Cetuximab i 125 · Radiopharmaceutical agent · Unclassified drug · Biological activity · Controlled study · Drug purity · Gel permeation chromatography · High performance liquid chromatography · Human cell · Immunoreactivity · Iodination · Isotope labeling · Luminescence · Radioactivity · Radiochemistry · Reaction time · Thin layer chromatography · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[PDF] [Abstract]

2 Acute effects on brain cholecystokinin-like concentration and anxiety-like behaviour in the female rat upon a single injection of 17β-estradiol
article 2014    
Author: Holm, L. · Liang, W. · Thorsell, A. · Hilke, S.
Keywords: Biology · Anxiety · Cholecystokinin · Estrogen · Cholecystokinin · Estradiol · Amygdaloid nucleus · Animal experiment · Animal tissue · Brain region · Cingulate gyrus · Comparative study · Controlled study · Estrogen synthesis · Estrus cycle · Female · Hippocampus · Immunoreactivity · Nonhuman · Nucleus accumbens · Ovariectomy · Panic · Priority journal · Punch biopsy · Rat · Single drug dose · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Evaluation of monoclonal antibodies with specificity for human IgA, IgA subclasses and allotypes and secretory component. Results of an IUIS/WHO collaborative study
article 1996    
Author: Mestecky, J. · Hamilton, R.G. · Magnusson, C.G.M. · Jefferis, R. · Vaerman, J.P. · Goodall, M. · Lange, G.G. de · Moro, I. · Aucouturier, P. · Radl, J. · Cambiaso, C. · Silvain, C. · Preud'homme, J.L. · Kusama, K. · Carlone, G.M. · Biewenga, J. · Kobayashi, K. · Skvaril, F. · Reimer, C.B.
Keywords: Biology · (Human) · Am allotype · IgA · IgA subclass · Monoclonal antibody · Specificity · immunoglobulin a · immunoglobulin subclass · monoclonal antibody · antigen antibody reaction · article · controlled study · diagnostic value · enzyme immunoassay · human · immunoblotting · immunodiffusion · immunohistology · immunoreactivity · priority journal · serum · Animals · Antibodies, Monoclonal · Antibody Specificity · Binding Sites, Antibody · Epitopes · Humans · Immunoglobulin A · Immunoglobulin A, Secretory · Immunoglobulin Allotypes · Immunologic Techniques · Mice · Reference Standards · Secretory Component
[Abstract]

4 Age-related changes in immune reactivity: The influence of intrinsic defects and of a changed composition of the CD4+ T cell compartment
article 1992    
Author: Nijhuis, E.W.P. · Nagelkerken, L.
Keywords: Biology · CD4+ T cell subsets · CD45 isoforms · Interleukin-4 · Cd4 antigen · Cd45 antigen · Immunoreactivity · Immunoregulation · Memory cell · T lymphocyte · T lymphocyte activation · T lymphocyte subpopulation · Thymus · Aging · Animal · Antigens, CD45 · CD4-Positive T-Lymphocytes · Human · Immunocompetence · Immunologic Memory · Interleukin-2 · Leukocyte Count · Mice · Thymus Gland
[Abstract]

5 Clinical relevance of sensitization to lupine in peanut-sensitized adults
article 2009    
Author: Peeters, K.A.B.M. · Koppelman, S.J. · Penninks, A.H. · Lebens, A. · Bruijnzeel-Koomen, C.A.F.M. · Hefle, S.L. · Taylor, S.L. · Hoffen, E. van · Knulst, A.C.
Keywords: Health · Toxicology and Applied Pharmacology · Clinical relevance · Double-blind placebo-controlled food challenge · Lupine allergy · Peanut · Sensitization · immunoglobulin E antibody · adolescent · adult · antibody blood level · antibody specificity · article · clinical article · controlled study · cross reaction · human · immunoreactivity · lupin · lupin allergy · morbidity · patient education · pea · peanut allergy · prick test · priority journal · soybean
[Abstract]

6 FcR interactions do not play a major role in inhibition of experimental autoimmune encephalomyelitis by anti-CD154 monoclonal antibodies
article 2004    
Author: Nagelkerken, L. · Haspels, I. · Rijs, W. van · Blauw, B. · Ferrant, J.L. · Hess, D.M. · Garber, E.A. · Taylor, F.R. · Burkly, L.C.
Keywords: CD40 ligand monoclonal antibody · allergic encephalomyelitis · allotransplantation · animal cell · animal experiment · animal model · cell infiltration · complement fixation · controlled study · fluorescence activated cell sorting · glycosylation · immunoreactivity · lymphocyte depletion · mouse · nonhuman · Th1 cell · Animals · Antibodies, Monoclonal · B-Lymphocytes · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Glycosylation · Mice · Myelin Proteolipid Protein · Peptide Fragments · Receptors, Fc · T-Lymphocytes
[Abstract]

7 Is Candida albicans a trigger in the onset of coeliac disease?
article 2003    
Author: Nieuwenhuizen, W.F. · Pieters, R.H.H. · Knippels, L.M.J. · Jansen, M.C.J.F. · Koppelman, S.J.
Keywords: Biology Toxicology · Food technology · autoantibody · blood clotting factor 13a · epitope · gliadin · gluten · hyphal wall protein 1 · protein glutamine gamma glutamyltransferase · unclassified drug · virulence factor · amino acid sequence · antibody production · article · autoimmune disease · Candida albicans · candidiasis · celiac disease · covalent bond · enzyme activity · genetic predisposition · human · immunoreactivity · intestine epithelium · intestine flora · nonhuman · pathophysiology · priority journal · protein expression · sequence analysis · sequence homology · Antibody Formation · Candida albicans · Celiac Disease · Fungal Proteins · Genetic Predisposition to Disease · Gliadin · Humans · Intestinal Mucosa · Membrane Glycoproteins · Transglutaminases · Virulence
[Abstract]

8 Assessment of protein allergenicity on the basis of immune reactivity: Animal models
article 2003    
Author: Kimber, I. · Dearman, R.J. · Penninks, A.H. · Knipples, L.M.J. · Buchanan, R.B. · Hammerberg, B. · Jackson, H.A. · Helm, R.M.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Allergy · Dog · Hazard identification · IgE · IgG · Immunogenicity · Mouse · Rat · Risk assessment · Swine · food allergen · protein · allergenicity · animal experiment · biotechnology · DNA modification · dog · food allergy · food intake · food safety · immunoreactivity · methodology · microorganism · nonhuman · priority journal · retrospective study · review · swine · world health organization · Administration, Oral · Animals · Dietary Proteins · Disease Models, Animal · Dogs · Food Hypersensitivity · Humans · Infusions, Parenteral · Mice · Mice, Inbred BALB C · Peanut Hypersensitivity · Rats · Risk Assessment · Swine · Animalia · Canis familiaris · Sus scrofa
[Abstract]

9 Repeated dose oral toxicological evaluation of concentrated barley β-glucan in CD-1 mice including a recovery phase
article 2003    
Author: Delaney, B. · Carlson, T. · Zheng, G.-H. · Hess, R. · Knutson, N. · Frazer, S. · Ostergren, K. · Zijverden, M. van · Knippels, L. · Jonker, D. · Penninks, A.
Keywords: Toxicology Biology · Toxicology and Applied Pharmacology · beta glucan · animal experiment · animal tissue · article · barley · controlled study · evaluation · female · hematological parameters · histopathology · immunoreactivity · lymph node · lymphoid organ · male · mouse · nonhuman · oat · organ weight · toxicity testing · Animal Feed · Animals · Diet · Dietary Fiber · Dose-Response Relationship, Drug · Drug Administration Schedule · Female · Glucans · Hematologic Tests · Hordeum · Lymphoid Tissue · Male · Mice · Mice, Inbred Strains · Toxicity Tests · Animalia · Avena · Hordeum vulgare subsp. vulgare
[Abstract]

10 Children with peanut allergy recognize predominantly Ara h2 and Ara h6, which remains stable over time
article 2007    
Author: Flinterman, A.E. · Hoffen, E. van · Hartog Jager, C.F. den · Koppelman, S. · Pasmans, S.G. · Hoekstra, M.O. · Bruijnzeel-Koomen, C.A. · Knulst, A.C. · Knol, E.F.
Keywords: Nutrition · Food technology · Ara h2 and Ara h6 · Children · IgE reactivity · Peanut allergy · Stable individual recognition · immunoglobulin E · adolescent · antigen recognition · article · child · clinical article · controlled study · female · human · immunoblotting · immunoreactivity · male · peanut allergy · prick test · priority journal · provocation test · skin test · Adolescent · Adult · Allergens · Antibody Specificity · Child · Child, Preschool · Double-Blind Method · Female · Glycoproteins · Humans · Immunoblotting · Immunoglobulin E · Male · Peanut Hypersensitivity · Plant Proteins · Skin Tests · Time Factors
[Abstract]

11 Autoantibodies against alpha B-crystallin, a candidate autoantigen in multiple sclerosis, are part of a normal human immune repertoire
article 2006    
Author: Noort, J.M. van · Verbeek, R. · Meilof, J.F. · Polman, C.H. · Amor, S.
Keywords: Health · Biomedical Research · Alpha B-crystallin · Determinant spreading · Alpha crystallin · Autoantibody · Immunoglobulin A · Immunoglobulin G · Immunoglobulin M · Antigen antibody reaction · Cellular immunity · Clinical article · Controlled study · Disease association · Eye inflammation · Immune response · Immunoglobulin blood level · Immunoreactivity · T lymphocyte · Adult · alpha-Crystallin B Chain · Antibody Specificity · Autoantibodies · Autoantigens · Chromatography, High Pressure Liquid · Electrophoresis, Polyacrylamide Gel · Eye Proteins · Female · Humans · Immune System · Lens, Crystalline · Male · Middle Aged · Multiple Sclerosis · Uveitis
[Abstract]

12 The effect of the food matrix on In Vivo immune responses to purified peanut allergens
article 2005    
Author: Wijk, F. van · Nierkens, S. · Hassing, I. · Feijen, M. · Koppelman, S.J. · Jong, G.A.H. de · Pieters, R. · Knippels, L.M.J.
Keywords: Nutrition Toxicology · Food technology · Food matrix · Immunogenicity · Mouse model · Peanut allergens · allergen · cholera toxin · cytokine · immunoglobulin E · allergenicity · animal cell · animal experiment · antigen presenting cell · antigen purification · article · assay · cell count · controlled study · cytokine production · feeding · female · food allergy · foot pad · immune response · immunogenicity · immunoreactivity · immunostimulation · in vivo study · lymph node · mouse · mouse strain · nonhuman · peanut · Allergens · Animals · Antigens, CD · Antigens, CD80 · Antigens, CD86 · Arachis hypogaea · Cholera Toxin · Cytokines · Dietary Fats · Female · Glycoproteins · Immunoglobulin E · Immunoglobulin G · Intercellular Adhesion Molecule-1 · Lymph Nodes · Membrane Glycoproteins · Mice · Mice, Inbred BALB C · Mice, Inbred C3H · Peanut Hypersensitivity · Plant Proteins · Ara · Arachis hypogaea
[Abstract]

13 Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice
article 2006    
Author: Valverde-Franco, G. · Binette, J.S. · Li, W. · Wang, H. · Chai, S. · Laflamme, F. · Tran-Khanh, N. · Quenneville, E. · Meijers, T. · Poole, A.R. · Mort, J.S. · Buschmann, M.D. · Henderson, J.E.
Keywords: Collagenase 3 · Core protein · Epitope · Fibroblast growth factor receptor 3 · Proteoglycan · Animal cell · Animal experiment · Animal model · Animal tissue · Cartilage degeneration · Cartilage matrix · Cell structure · Compression · Controlled study · Genetic procedures · Humerus head · Hypertrophy · Immunoreactivity · Mouse · Nonhuman · Physical resistance · Protein deficiency · Protein degradation · Protein expression · Protein targeting · Rigidity · Signal transduction · Synovium · Tissue metabolism · Aggrecans · Animals · Arthritis · Cartilage · Cartilage Diseases · Cartilage, Articular · Chondrocytes · Collagen Type II · Collagen Type X · Collagenases · Crosses, Genetic · Epitopes · Extracellular Matrix Proteins · Lectins, C-Type · Matrix Metalloproteinase 13 · Mice · Mice, Transgenic · Osteoblasts · Proteochondroitin Sulfates · Receptor, Fibroblast Growth Factor, Type 3 · Signal Transduction
[Abstract]

14 Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis
article 2007    
Author: Kel, J. · Oldenampsen, J. · Luca, M. · Drijfhout, J.W. · Koning, F. · Nagelkerken, L.
Keywords: Biology · Biomedical Research · gamma interferon · interleukin 23 · major histocompatibility antigen class 2 · myelin · proteolipid · autoantigen · epitope · lymphocyte antigen receptor · mannose · peptide fragment · proteolipid protein · proteolipid protein 139 151 · proteolipid protein 139-151 · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · female · histopathology · immunization · immunomodulation · immunoreactivity · incidence · macrophage · mouse · nonhuman · priority journal · solubility · spinal cord · T lymphocyte · animal · chemistry · drug effect · immunology · inflammation · lymphocyte activation · pathology · Animals · Autoantigens · Encephalomyelitis, Autoimmune, Experimental · Female · Immunodominant Epitopes · Inflammation · Lymphocyte Activation · Mannose · Mice · Myelin Proteolipid Protein · Peptide Fragments · Receptors, Antigen, T-Cell · Spinal Cord · T-Lymphocytes
[Abstract]

15 Immunologic activity of schistosomal and bacterial TLR2 ligands in Gabonese children
article 2008    
Author: Retra, K. · Riet, E. van · Adegnika, A.A. · Everts, B. · Geest, S. van · Kremsner, P.G. · Hellemond, J.J. van · Kleij, D. van der · Tielens, A.G.M. · Yazdanbakhsh, M.
Keywords: Biology · Lysophosphatidylserine · MALP-2 · Monoacylglycerophosphoserine · PAM 3CSK4 · Schistosoma mansoni · Th1 · Th2 · Toll-like receptor · Interleukin 10 · Ligand · Lysophosphatidylserine · Phosphatidylserine · Toll like receptor 2 · Tumor necrosis factor alpha · Adolescent · Blood culture · Child · Clinical article · Endemic disease · Female · Humans · Immune system · Immunoreactivity · Immunoregulation · Lipid analysis · Male · Schistosoma · Schistosomiasis · Statistical analysis · Animals · Cell Line · Child, Preschool · Cytokines · Gabon · Lysophospholipids · Oligopeptides · Peptides · Schistosoma mansoni · Toll-Like Receptor 2 · Bacteria (microorganisms) · Schistosoma mansoni · Toll like receptor 2, 203811-81-8 · Cytokines · Lysophosphatidylserine · Macrophage stimulatory lipopeptide 2 · Pam(3)CSK(4) peptide · Life · CBRN - CBRN Protection · ELSS - Earth, Life and Social Sciences
[Abstract]

16 Respiratory sensitization : Advances in assessing the risk of respiratory inflammation and irritation
article 2011    
Author: Vandebriel, R. · Callant Cransveld, C. · Crommelin, D. · Diamant, Z. · Glazenburg, B. · Joos, G. · Kuper, F. · Natsch, A. · Nijkamp, F. · Noteborn, H. · Pieters, R. · Roberts, D. · Roggen, E. · Rorije, E. · Seed, M. · Sewald, K. · Heuvel, R. van den · Engelen, J. van · Verstraelen, S. · Loveren, H. van
Keywords: Toxicology · ASAT · Asthma · In vitro · In vivo · Integrated testing · QSAR · Respiratory tract · Rhinitis · Risk assessment · Sensitization · contact allergen · immunoglobulin E · airway remodeling · animal testing alternative · biosafety · bronchus hyperreactivity · cell assay · cellular immunity · dendritic cell · disease predisposition · functional genomics · human · immunopathology · immunoreactivity · in vitro study · mathematical model · mucosal immunity · nonhuman · occupational asthma · predictive value · process development · process model · quantitative analysis · quantitative structure activity relation · reaction analysis · respiratory sensitization · respiratory tract inflammation · respiratory tract injury · review · risk assessment · risk factor · sensitization · Animal Testing Alternatives · Hazardous Substances · Humans · Respiratory Hypersensitivity · Respiratory Tract Diseases · Toxicity Tests · Animalia · Healthy for Life · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

17 Human osteoblasts produce cathepsin K
article 2006    
Author: Mandelin, J. · Hukkanen, M. · Li, T.F. · Korhonen, M. · Liljeström, M. · Sillat, T. · Hanemaaijer, R. · Salo, J. · Santavirta, S. · Konttinen, Y.T.
Keywords: Biomedical Research · Cathepsin K · Cytokines · Osteoblasts · Osteoporosis · Stromal cells · antibody · cathepsin K · collagen type 1 · messenger RNA · bone matrix · cell isolation · controlled study · culture medium · femur neck · fracture · human · human cell · human tissue · immunoassay · immunohistochemistry · immunoreactivity · nucleotide sequence · osteoblast · osteocyte · protein analysis · protein function · protein secretion · protein synthesis · quantitative analysis · reverse transcription polymerase chain reaction · RNA analysis · sampling · trabecular bone · Western blotting · Alkaline Phosphatase · Calcification, Physiologic · Cathepsins · Cell Differentiation · Cells, Cultured · Core Binding Factor Alpha 1 Subunit · Gene Expression Regulation · Humans · Immunohistochemistry · Matrix Metalloproteinase 13 · Mesenchymal Stem Cells · Osteoclasts · Osteoprotegerin · RANK Ligand · RNA, Messenger · Tumor Necrosis Factor-alpha
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 17 of 17 found. | Sort by date