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1 The ethanolamide metabolite of DHA, docosahexaenoylethanolamine, shows immunomodulating effects in mouse peritoneal and RAW264.7 macrophages: Evidence for a new link between fish oil and inflammation
article 2011    
Author: Meijerink, J. · Plastina, P. · Vincken, J.P. · Poland, M. · Attya, M. · Balvers, M. · Gruppen, H. · Gabriele, B. · Witkamp, R.F.
Keywords: Nutrition · DHA · Docosahexaenoylethanolamine · Inflammation · Macrophages · Monocyte chemotactic protein-1 · Nitric oxide · Life · QS - Quality & Safety MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

2 Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration
article 2014    
Author: Wang, Y. · Parlevliet, E.T. · Geerling, J.J. · Tuin, S.J.L. van der · Zhang, H. · Bieghs, V. · Jawad, A.H.M. · Shiri-Sverdlov, R. · Bot, I. · Jager, S.C.A. de · Havekes, L.M. · Romijn, J.A. · Willems Van Dijk, K. · Rensen, P.C.N.
Keywords: Biology · Cholesterol · Exendin-4 · Inflammation · Macrophage content · Monocyte recruitment · Oxidized LDL · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin
article 2008    
Author: Haan, W. de · Vries-van der Weij, J. de · Hoorn, J.W.A. van der · Gautier, T. · Hoogt, C.C. van der · Westerterp, M. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Princen, H.M.G. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Atherosclerosis · Cholesteryl ester transfer proteins · Drugs · Lipids · Lipoproteins · Apolipoprotein E · Atorvastatin · Cholesterol · Cholesterol ester transfer protein · Collagen · High density lipoprotein cholesterol · Monocyte chemotactic protein 1 · Torcetrapib · Atherosclerosis · Cholesterol blood level · Drug activity · Evaluation · Female · Inflammation · Macrophage · Monocyte · Mouse · Nonhuman · Phenotype · Sham feeding · Statistical significance · Animals · Atherosclerosis · Cholesterol Ester Transfer Proteins · Drug Synergism · Heptanoic Acids · Inflammation · Mice · Mice, Inbred Strains · Pyrroles · Quinolines
[PDF] [Abstract]

4 Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: Evidence for antiinflammatory effects of rosuvastatin
article 2003    
Author: Kleemann, R. · Princen, H.M.G. · Emeis, J.J. · Jukema, J.W. · Fontijn, R.D. · Horrevoets, A.J.G. · Kooistra, T. · Havekes, L.M.
Keywords: Biology · Biomedical Research · Cell adhesion molecules · Inhibitors · Amyloid A protein · Cell adhesion molecule · Fibrinogen · Monocyte chemotactic protein 1 · Rosuvastatin · Statine derivative · Tumor necrosis factor alpha · Antiinflammatory agent · Apolipoprotein E · Apolipoprotein E3 (Leidein) · Cytokine · Fluorobenzene · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Lipid · Lipoprotein · Pyrimidine derivative · Sulfonamide · Animal cell · Animal experiment · Animal model · Animal tissue · Aorta root · Cell adhesion · Cholesterol blood level · Cholesterol diet · Controlled study · Inflammation · Monocyte · Mouse · Nonhuman · Nucleotide sequence · Transgenic mouse · Blood · Drug effect · Genetics · Immunology · Metabolism · Pathology · Animals · Anti-Inflammatory Agents · Aorta · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Cell Adhesion · Cholesterol · Cytokines · Female · Fluorobenzenes · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lipids · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Monocytes · Pyrimidines · Sulfonamides
[Abstract]

5 Anti-MCP-1 gene therapy inhibits vascular smooth muscle cells proliferation and attenuates vein graft thickening both in vitro and in vivo
article 2006    
Author: Schepers, A. · Eefting, D. · Bonta, P.I. · Grimbergen, J.M. · Vries, M.R. de · Weel, V. van · Vries, C.J. de · Egashira, K. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Inflammation · Intimal hyperplasia · MCP-1 · Smooth muscle cells · Vein graft disease · Apolipoprotein E · Chemokine receptor CCR2 · Monocyte chemotactic protein 1 · Animal experiment · Animal model · Animal tissue · Artery intima proliferation · Atherosclerosis · Carotid artery · Cell proliferation · Controlled study · Graft failure · Human · Human cell · Human tissue · Hypercholesterolemia · In vitro study · In vivo study · Monocyte · Mouse · Nonhuman · Protein expression · Saphenous vein · Vascular smooth muscle · Vein graft · Amino Acid Sequence · Animals · Carotid Arteries · Cell Proliferation · Cells, Cultured · Chemokine CCL2 · Gene Therapy · Humans · Hypercholesterolemia · Male · Mice · Mice, Inbred C57BL · Muscle, Smooth, Vascular · Myocytes, Smooth Muscle · Organ Culture Techniques · Receptors, Chemokine · Saphenous Vein · Sequence Deletion · Tunica Intima
[Abstract]

6 Insights into mechanisms behind arteriogenesis: What does the future hold?
article 2008    
Author: Oostrom, M.C. van · Oostrom, O. van · Quax, P.H.A. · Verhaar, M.C. · Hoefer, I.E.
Keywords: Cell therapy · Growth factors · growth factor · monocyte chemotactic protein 1 · vasculotropin · vasculotropin A · vasculotropin B · vasculotropin C · vasculotropin D · angiogenesis · blood flow · cell differentiation · cell therapy · cell type · clinical trial · human · neovascularization (pathology) · priority journal · review · Angiogenesis Inducing Agents · Arterial Occlusive Diseases · Collateral Circulation · Humans · Neovascularization, Physiologic
[Abstract]

7 Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties
article 2010    
Author: Balvers, M.G.J. · Verhoeckx, K.C.M. · Plastina, P. · Wortelboer, H.M. · Meijerink, J. · Witkamp, R.F.
Keywords: Biology · Biomedical Research · Adipocytes · DHA · EPA · Inflammation · N-acyl ethanolamines · docosahexaenoic acid · docosahexaenoyl ethanolamine · eicosapentanaenoyl ethanolamine · icosapentaenoic acid · interleukin 6 · lipopolysaccharide · monocyte chemotactic protein 1 · n acyl ethanolamine · unclassified drug · antiinflammatory activity · article · cell strain 3T3 · enzyme structure · enzyme synthesis · nonhuman · priority journal
[Abstract]

8 The contact allergen dinitrochlorobenzene (DNCB) and respiratory allergy in the Th2-prone Brown Norway rat
article 2008    
Author: Kuper, C.F. · Stierum, R.H. · Boorsma, A. · Schijf, M.A. · Prinsen, M. · Bruijntjes, J.P. · Bloksma, N. · Arts, J.H.E.
Keywords: Health · Dinitrochlorobenzene · LLNA · MCP-1 · MIP1-beta · Respiratory allergy · Skin allergy · 1 chloro 2,4 dinitrobenzene · CD4 antigen · immunoglobulin G · macrophage inflammatory protein 1beta · monocyte chemotactic protein 1 · monocyte chemotactic protein 3 · thymus and activation regulated chemokine · animal experiment · animal model · animal tissue · article · controlled study · female · lung function · lung lavage · lung parenchyma · male · microarray analysis · nonhuman · Norway · nucleotide sequence · priority journal · rat · respiratory tract allergy · skin allergy · skin irritation · skin sensitization · Th2 cell · upregulation · Administration, Cutaneous · Allergens · Animals · Dermatitis, Allergic Contact · Dinitrochlorobenzene · Female · Immunoglobulin E · Immunoglobulin G · Inhalation Exposure · Irritants · Local Lymph Node Assay · Lung · Lymph Nodes · Male · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Hypersensitivity · Th2 Cells · Animalia · Rattus · Rattus norvegicus
[Abstract]

9 Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin
article 2014    
Author: Kühnast, S. · Hoorn, J.W.A. van der · Pieterman, E.J. · Hoek, A.M. van den · Sasiela, W.J. · Gusarova, V. · Peyman, A. · Schäfer, H.L. · Schwahn, U. · Jukema, J.W. · Princen, H.M.G.
Keywords: Biology · 3Leiden.CETP mice · APOE · Atorvastatin · Proprotein convertase subtilisin/kexin type 9 · Alirocumab · Apolipoprotein E · Atorvastatin · Bile acid · Cholesterol · Collagen · Low density lipoprotein receptor · Sterol · Triacylglycerol · Animal experiment · Animal model · Atherosclerosis · Atherosclerotic plaque · Controlled study · Disease severity · Dose response · Drug effect · Drug potentiation · Drug safety · Fat content · Female · Lipid blood level · Monocyte · Monotherapy · Mouse · Nonhuman · Protein degradation · Smooth muscle fiber · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

10 The bradykinin B2 receptor in the early immune response against Listeria infection
article 2009    
Author: Kaman, W.E. · Wolterink, A.F.W.M. · Bader, M. · Boele, L.C.L. · Kleij, D. van der
Keywords: Biology · Bradykinin · Cytokines · Knock out mice · Listeria monocytogenes · Bradykinin B2 receptor · Gamma interferon · Interleukin 12p70 · Animal experiment · Animal model · Article · Controlled study · Cytokine production · Dendritic cell · Immune response · Lsteria monocytogenes · Listeriosis · Monocyte · Mouse · Nonhuman · Priority journal · Protein function · Weight reduction · Animals · Body Weight · Bradykinin · Cells, Cultured · Cytokines · Dendritic Cells · Humans · Interferon-gamma · Interleukin-12 · Listeria Infections · Listeria monocytogenes · Liver · Mice · Mice, Knockout · Receptor, Bradykinin B2
[Abstract]

11 Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice, a translational model for atherosclerosis
article 2014    
Author: Gierman, L.M. · Kühnast, S. · Koudijs, A. · Pieterman, E.J. · Kloppenburg, M. · Osch, G.J.V.M. van · Stojanovic-Susulic, V. · Huizinga, T.W.J. · Princen, H.M.G. · Zuurmond. A.M.
Keywords: Biology · Alanine aminotransferase · Apolipoprotein E · Atorvastatin · Cholesterol ester transfer protein · Endothelial leukocyte adhesion molecule 1 · Etimibe · Monocyte chemotactic protein 1 · Serum amyloid A · Very low density lipoprotein · Animal experiment · Animal model · Animal tissue · Atherosclerosis · Cholesterol blood level · Cholesterol intake · Controlled study · Female · Knee osteoarthritis · Mouse · Nonhuman · Priority journal · Transgenic mouse · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

12 The β-adrenoceptor agonist clenbuterol is a potent inhibitor of the LPS-induced production of TNF-α and IL-6 in vitro and in vivo
article 1999    
Author: Izeboud, C.A. · Monshouwer, M. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: Nutrition · β-agonists · Clenbuterol · Cytokines · Lipopolysaccharide · Macrophages · Beta adrenergic receptor stimulating agent · Clenbuterol · Interleukin 6 · Lipopolysaccharide · Tumor necrosis factor alpha · Animal cell · Bioassay · Blood level · Controlled study · Culture medium · Cytokine production · Enzyme linked immunosorbent assay · Human · Human cell · Inflammation · Macrophage · Male · Monocyte · Nonhuman · Oral drug administration · Rat · Adrenergic beta-Agonists · Animals · Cell Line · Clenbuterol · Escherichia coli · Humans · Interleukin-6 · Lipopolysaccharides · Macrophages · Male · Rats · Rats, Wistar · Tumor Necrosis Factor-alpha
[Abstract]

13 Participation of β-adrenergic receptors on macrophages in modulation of LPS-induced cytokine release
article 1999    
Author: Izeboud, C.A. · Mocking, J.A.J. · Monshouwer, M. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: Nutrition · Beta 2 adrenergic receptor stimulating agent · Beta adrenergic receptor · Clenbuterol · Cytokine · Interleukin 10 · Interleukin 6 · Lipopolysaccharide · Radioligand · Tumor necrosis factor alpha · Antiinflammatory activity · Cell culture · Conference paper · Cytokine production · Drug receptor binding · Human · Human cell · Inflammation · Macrophage · Macrophage activation · Monocyte · Receptor binding · Receptor intrinsic activity · Adrenergic beta-Agonists · Adrenergic beta-Antagonists · Atenolol · Clenbuterol · Cytokines · Humans · Interleukin-10 · Interleukin-6 · Lipopolysaccharides · Macrophage Activation · Macrophages · Propanolamines · Receptors, Adrenergic, beta · Tumor Necrosis Factor-alpha · U937 Cells
[Abstract]

14 A combination of proteomics, principal component analysis and transcriptomics is a powerful tool for the identification of biomarkers for macrophage maturation in the U937 cell line
article 2004    
Author: Verhoeckx, K.C.M. · Bijlsma, S. · Groene, E.M. de · Witkamp, R.F. · Greef, J. van der · Rodenburg, R.J.T.
Keywords: Pharmacology · Analytical research · Differentiation markers · Macrophage maturation · Oligonucleotide microarray · Principal component analysis · Two-dimensional gel electrophoresis · complementary DNA · oligonucleotide · peptide · protein · RNA · analytic method · article · cell differentiation · cell strain U937 · genetic transcription · human · human cell · immunoblotting · lymphoma cell · macrophage · mass spectrometry · matrix assisted laser desorption ionization time of flight mass spectrometry · monocyte · nucleotide sequence · peptide analysis · polyacrylamide gel electrophoresis · polymerase chain reaction · principal component analysis · priority journal · proteomics · two dimensional gel electrophoresis · Cell Differentiation · Electrophoresis, Gel, Two-Dimensional · Gene Expression Profiling · Gene Expression Regulation · Humans · Macrophages · Monocytes · Principal Component Analysis · Proteome · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Statistics · Tetradecanoylphorbol Acetate · U937 Cells
[Abstract]

15 Erosive arthritis in a patient with pycnodysostosis: An experiment of nature
article 2008    
Author: Ainola, M. · Valleala, H. · Nykänen, P. · Risteli, J. · Hanemaaijer, R. · Konttinen, Y.T.
Keywords: Health · acid phosphatase tartrate resistant isoenzyme · calcitonin receptor · carboxy terminal telopeptide · cathepsin K · folic acid · hydroxychloroquine · ketoprofen · matrix metalloproteinase · messenger RNA · methotrexate · n [n (3 carboxyoxirane 2 carbonyl)leucyl]agmatine · prednisolone · salazosulfapyridine · adult · article · bone defect · bone erosion · case report · collagen degradation · controlled study · drug withdrawal · dysostosis · female · hand radiography · human · human cell · monocyte · multinuclear cell · nucleotide sequence · osteoclast · osteolysis · priority journal · psoriatic arthritis · pyknodysostosis · rash · synovitis · Acid Phosphatase · Arthritis, Psoriatic · Bone Resorption · Cathepsins · Cells, Cultured · Dysostoses · Female · Humans · Middle Aged · Monocytes · Osteoclasts · Receptors, Calcitonin
[Abstract]

16 PET imaging of disease progression and treatment effects in the experimental autoimmune encephalomyelitis rat model
article 2014    
Author: Paula Faria, D. de · Vlaming, M.L.H. · Copray, S.C.V.M. · Tielen, F. · Anthonijsz, H.J.A. · Sijbesma, J.W.A. · Buchpiguel, C.A. · Dierckx, R.A.J.O. · Hoorn, J.W.A. van der · Vries, E.F.J. de
Keywords: Biology · Demyelination · Multiple sclerosis · Neuroinflammation · PET imaging · Dexamethasone acetate · MeDAS c 11 · Myelin oligodendrocyte glycoprotein · N sec butyl 1 (2 chlorophenyl) n methyl 3 isoquinolinecarboxamide c 11 · Radiopharmaceutical agent · Unclassified drug · Animal cell · Animal experiment · Animal model · Animal tissue · Brain region · Cell invasion · Controlled study · Demyelination · Disease course · Drug effect · Experimental autoimmune encephalomyelitis · Female · In vivo study · Microglia · Monocyte · Neuroimaging · Nonhuman · PET scanner · Positron emission tomography · Priority journal · Rat · Scoring system · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

17 Macrophage-specific inhibition of NF-κB activation reduces foam-cell formation
article 2007    
Author: Ferreira, V. · Dijk, K.W. van · Groen, A.K. · Vos, R.M. · Kaa, J. van der · Gijbels, M.J.J. · Havekes, L.M. · Pannekoek, H.
Keywords: Biology · Biomedical Research · ABCA1 mediated cholesterol efflux · Foam cell formation · Macrophage specific inhibition of NF-κB, IκBα · ox-LDL-PPARγ-CD36 "feed-forward cycle" · I kappa B kinase alpha · immunoglobulin enhancer binding protein · article · cell differentiation · cell line · cell specificity · controlled study · cytoplasm · foam cell · gene expression · human · human cell · lipid oxidation · lipid transport · monocyte · mouse · nonhuman · peritoneum cell · priority journal · protein degradation · protein expression · transgenic mouse · Animals · Antigens, CD36 · ATP-Binding Cassette Transporters · Cell Line · DNA-Binding Proteins · Foam Cells · Humans · I-kappa B Proteins · Lipoproteins, LDL · Macrophages · Mice · Mice, Inbred C57BL · NF-kappa B · PPAR gamma · Receptors, Cytoplasmic and Nuclear · Scavenger Receptors, Class A
[Abstract]

18 Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice
article 2009    
Author: Eefting, D. · Bot, I. · Vries, M.R. de · Schepers, A. · Bockel, J.H. van · Berkel, T.J.C. van · Biessen, E.A.L. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · apolipoprotein E3 · chemokine receptor CCR2 · lentiviral short hairpin RNA · lentivirus vector · messenger RNA · monocyte chemotactic protein 1 · unclassified drug · animal cell · animal model · article · atherosclerosis · carotid artery · cell migration · cell proliferation · clinical feature · controlled study · disease course · drug delivery system · drug efficacy · drug targeting · gene silencing · gene therapy · hypercholesterolemia · in vitro study · in vivo study · infection · Lentivirinae · male · morphometrics · mouse · nonhuman · priority journal · protein expression · receptor upregulation · smooth muscle fiber · treatment outcome · vein graft · vein graft disease · vein surgery · viral gene delivery system · Animals · Apolipoprotein E3 · Atherosclerosis · Chemokine CCL2 · Disease Models, Animal · Graft Occlusion, Vascular · Hypercholesterolemia · Lentivirus · Male · Mice · Receptors, CCR2 · RNA Interference · Veins
[Abstract]

19 Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein
article 1998    
Author: Schalkwijk, C.G. · Vermeer, M.A. · Stehouwer, C.D.A. · Koppele, J. te · Princen, H.M.G. · Hinsbergh, V.W.M. van
Keywords: Biology · Advanced glycation end product · Diabetes · Low density lipoprotein · Methylglyoxal · Arginine · Cholesterol ester · Cytochrome c · Iodine 125 · Low density lipoprotein · Low density lipoprotein receptor · Lysine · Methylglyoxal · Monocyte chemotactic protein 1 · Oxidized low density lipoprotein · Superoxide · Vasculotropin · Controlled study · Fluorescence · Human · Human cell · Isotope labeling · Lipid metabolism · Macrophage · Plasma clearance · Priority journal · Receptor affinity · Animals · Cell Line · Chemistry, Physical · Cytochrome c Group · Electrochemistry · Endothelium, Vascular · Fibroblasts · Humans · Lipid Peroxidation · Lipid Peroxides · Lipoproteins, LDL · Macrophages · Malondialdehyde · Mice · Oxidation-Reduction · Pyruvaldehyde · Receptors, LDL · Superoxides · Thiobarbituric Acid Reactive Substances · Murinae
[Abstract]

20 Fenofibrate reduces atherogenesis in ApoE*3Leiden mice: Evidence for multiple antiatherogenic effects besides lowering plasma cholesterol
article 2006    
Author: Kooistra, T. · Verschuren, L. · Vries de-Weij, J.van der · Koenig, W. · Toet, K. · Princen, H.M.G. · Kleemann, R.
Keywords: Biology · Biomedical Research · Atherosclerosis · Fibrates · Inflammation · Pleiotrop · Reverse cholesterol transport · ABC transporter A1 · Cholesterol · Fenofibrate · Granulocyte macrophage colony stimulating factor · Immunoglobulin enhancer binding protein · Intercellular adhesion molecule 1 · Monocyte chemotactic protein 1 · Serum amyloid A · Vascular cell adhesion molecule 1 · Animal cell · Animal experiment · Animal model · Animal tissue · Aorta atherosclerosis · Atherogenesis · Cholesterol blood level · Cholesterol diet · Cholesterol transport · Controlled study · Disease severity · Drug effect · Macrophage · Mouse · Nonhuman · Protein blood level · Protein expression · Transgenic mouse · Upregulation · Animals · Antilipemic Agents · Aorta · Aortic Valve · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Cholesterol · Female · Inflammation · Lipids · Lipoproteins · Mice · Mice, Transgenic · Procetofen
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 32 found. Next | Sort by date