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1 Regulatory developmental neurotoxicity testing: A model study focussing on conventional neuropathology endpoints and other perspectives
article 2005    
Author: Groot, D.M.G.de · Bos-Kuijpers, M.H.M. · Kaufmann, W.S.H. · Lammers, J.H.C.M. · O'Callaghan, J.P. · Pakkenberg, B. · Pelgrim, M.T.M. · Waalkens-Berendsen, I.D.H. · Waanders, M.M. · Gundersen, H.J.J.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Methylazoxy methanol acetate (MAM) · Microscopy and linear morphometry · Neuron numbers and stereology · Neuropathology endpoints · OECD 426) · OPPTS 870.8600, EPA · Rat · Regulatory developmental neurotoxicity (DNT) testing (Guidelines OPPTS 870.6300, EPA · methylazoxymethanol acetate · animal model · animal tissue · brain · brain development · brain size · conference paper · controlled study · developmental neurotoxicity testing · dissection · female · morphometrics · nerve cell · neuroanatomy · neuropathology · neurotoxicity · nonhuman · perinatal period · practice guideline · priority journal · qualitative analysis · rat · toxicity testing · Animalia
[Abstract]

2 Non-invasive measurement of brain damage in a primate model of multiple sclerosis
article 2004    
Author: T Hart, B.A. · Vogels, J. · Bauer, J. · Brok, H.P.M. · Blezer, E.
Keywords: Biology Health · Analytical research · myelin · allergic encephalomyelitis · brain injury · chemometric analysis · demyelination · diagnostic imaging · human · immunopathology · marmoset · multiple sclerosis · neurologic disease · neuropathology · non invasive measurement · nonhuman · nuclear magnetic resonance imaging · nuclear magnetic resonance spectroscopy · pattern recognition · positron emission tomography · proton nuclear magnetic resonance · review · urinalysis · white matter · X ray analysis · Animals · Animals, Outbred Strains · Antigens, CD · Biological Markers · Brain · Callithrix · CD4-Positive T-Lymphocytes · Chronic Disease · Demyelinating Diseases · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Genes, MHC Class II · Humans · Magnetic Resonance Imaging · Magnetic Resonance Spectroscopy · Mice · Multiple Sclerosis · Myelin Basic Proteins · Myelin-Associated Glycoprotein · T-Lymphocytes, Cytotoxic · Th2 Cells · Animalia · Callithrix · Callithrix jacchus · marmosets · Primates · Rodentia
[Abstract]

3 2D and 3D assessment of neuropathology in rat brain after prenatal exposure to methylazoxymethanol, a model for developmental neurotoxicty
article 2005    
Author: Groot, D.M.G. de · Hartgring, S. · Horst, L. van de · Moerkens, M. · Otto, M. · Bos-Kuijpers, M.H.M. · Kaufmann, W.S.H. · Lammers, J.H.C.M. · O'Callaghan, J.P. · Waalkens-Berendsen, I.D.H. · Pakkenberg, B. · Gundersen, H.G.
Keywords: Biology · Toxicology and Applied Pharmacology · Cerebellum · Developmental neurotoxicity · Hippocampus · Linear morphometry · Methylazoxymethanol · Neuron numbers · Rat · Stereology · methylazoxymethanol · animal experiment · animal model · animal tissue · article · brain development · brain size · brain weight · cell count · cell proliferation · cell structure · cerebellum · controlled study · developmental disorder · evaluation · female · hippocampus · linear system · male · morphometrics · neuropathology · neurotoxicity · nonhuman · pregnancy · prenatal exposure · progeny · pyramidal nerve cell · quantitative analysis · rat · stereology · strength · three dimensional imaging · Abnormalities, Drug-Induced · Animals · Animals, Outbred Strains · Brain · Cell Count · Female · Imaging, Three-Dimensional · Injections, Intraperitoneal · Male · Maternal Exposure · Methylazoxymethanol Acetate · Organ Size · Pregnancy · Prenatal Exposure Delayed Effects · Rats · Rats, Wistar · Specific Pathogen-Free Organisms · Teratogens · Toxicity Tests
[Abstract]

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