Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 17 of 17 found. | Sort by date

1 Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2
article 2006    
Author: Dihal, A.A. · Woutersen, R.A. · Ommen, B.v. · Rietjens, I.M.C.M. · Stierum, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Caco-2 · Colorectal cancer · Differentiation · Metabolism · Proliferation · Quercetin · 3' o methylquercetin 4' o glucuronide · 3' o methylquercetin 7 o sulfate · 4' o methylquercetin 3' o glucuronide · 4' o methylquercetin 7 o glucuronide · isorhamnetin · quercetin · quercetin derivative · unclassified drug · article · cell differentiation · cell proliferation · cell strain CACO 2 · controlled study · human · human cell · priority journal · statistical significance · Anticarcinogenic Agents · Caco-2 Cells · Cell Differentiation · Cell Proliferation · Colorectal Neoplasms · Drug Stability · Humans · Quercetin
[Abstract]

2 Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin
article 2003    
Author: Zanden, J.J. van · Hamman, O.B. · Iersel, M.L.P.S. van · Boeren, S. · Cnubben, N.H.P. · Lo Bello, M. · Vervoort, J. · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · Cysteine · Glutathione S-transferase · Inhibition · Quercetin · Quinone · ascorbic acid · cysteine · flavonoid · glutathione · glutathione transferase · isoenzyme · mutant protein · quercetin · article · chemical interaction · concentration response · covalent bond · dimerization · enzyme inhibition · human · incubation time · inhibition kinetics · time · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Glutathione Transferase · Humans · Mass Spectrometry · Molecular Structure · Monophenol Monooxygenase · Mutation · Quercetin
[Abstract]

3 Pathway and single gene analyses of inhibited Caco-2 differentiation by ascorbate-stabilized quercetin suggest enhancement of cellular processes associated with development of colon cancer
article 2007    
Author: Dihal, A.A. · Tilburgs, C. · Erk, M.J. van · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Toxicology and Applied Pharmacology · Caco-2 · Colorectal cancer · Differentiation · Microarray · Quercetin · ascorbic acid · quercetin · article · cell differentiation · cell division · cell strain CACO 2 · colon tumor · comparative study · DNA microarray · drug effect · drug stability · gene expression · genetics · human · pathology · Ascorbic Acid · Caco-2 Cells · Cell Differentiation · Cell Division · Colonic Neoplasms · Drug Stability · Gene Expression · Humans · Oligonucleotide Array Sequence Analysis · Quercetin
[Abstract]

4 Chronic quercetin exposure affects fatty acid catabolism in rat lung
article 2006    
Author: Boer, V.C.J. de · Schothorst, E.M. van · Dihal, A.A. · Woude, H. van der · Arts, I.C.W. · Rietjens, I.M.C.M. · Hollman, P.C.H. · Keijer, J.
Keywords: Biomedical Research · Fatty acid metabolism · Flavonoids · Microarray · Nutrigenomics · Polyphenols · Quercetin · fatty acid · quercetin · animal experiment · article · catabolism · controlled study · diet · genomics · health · ketogenesis · lung parenchyma · male · microarray analysis · nonhuman · nucleotide sequence · oxidation · quantitative analysis · rat · real time polymerase chain reaction · unindexed sequence · upregulation · Animals · Diet · Fatty Acids · Gene Expression Regulation · Lung · Male · Oligonucleotide Array Sequence Analysis · Quercetin · Rats · Rats, Inbred F344
[Abstract]

5 The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential
article 2007    
Author: Zanden, J.J. van · Woude, H. van der · Vaessen, J. · Usta, M. · Wortelboer, H.M. · Cnubben, N.H.P. · Rietjens, I.M.C.M.
Keywords: Biomedical Research · ABC transporters · Flavonoids · MRP1 · MRP2 · Phase II metabolism · Quercetin · ABC transporter · flavonoid · multidrug resistance protein 1 · multidrug resistance protein 2 · quercetin · animal cell · article · cancer cell culture · cancer chemotherapy · chemical structure · controlled study · enzyme activity · enzyme inhibition · glucuronidation · human · human cell · multidrug resistance · nonhuman · priority journal · rat · Animals · Cell Line, Tumor · Humans · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Quercetin · Rats
[Abstract]

6 Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats
article 2008    
Author: Schutte, M.E. · Alink, G.M. · Freidig, A.P. · Spenkelink, B. · Vaessen, J.C.H. · Sandt, J.J.M. van de · Groten, J.P. · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · ABC transporters · Caco-2 monolayers · In silico modelling · PhIP · Quercetin · Rat · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · quercetin · animal experiment · animal tissue · article · bioavailability · cell strain CACO 2 · computer model · controlled study · dietary intake · human · human cell · in vitro study · in vivo study · male · nonhuman · rat · Animals · Antioxidants · Area Under Curve · Biological Availability · Biological Transport, Active · Caco-2 Cells · Carcinogens · Humans · Imidazoles · Male · Models, Biological · Quercetin · Random Allocation · Rats · Rats, Wistar · Rattus
[Abstract]

7 Tissue distribution of quercetin in rats and pigs
article 2005    
Author: Boer, V.C.J. de · Dihal, A.A. · Woude, H. van der · Arts, I.C.W. · Wolffram, S. · Alink, G.M. · Rietjens, I.M.C.M. · Keijer, J. · Hollman, P.C.H.
Keywords: Biology · Physiological Sciences · Flavonoids · Glucuronides · Polyphenols · Quercetin · Tissue distribution · carbon 14 · flavonoid · glucuronide · isorhamnetin · polyphenol derivative · quercetin · tamarixetin · unclassified drug · animal experiment · animal tissue · article · bioavailability · brain · controlled study · extraction · feeding · half life time · heart · high performance liquid chromatography · kidney · lung · male · metabolite · nonhuman · nutrition · rat · spleen · statistical analysis · swine · tissue distribution · white adipose tissue · Animals · Biological Availability · Body Weight · Chromatography, High Pressure Liquid · Male · Quercetin · Rats · Rats, Inbred F344 · Swine · Tissue Distribution · Sus scrofa
[Abstract]

8 Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats
article 2006    
Author: Dihal, A.A. · Boer, V.C.J. de · Woude, H. van der · Tilburgs, C. · Bruijntjes, J.P. · Alink, G.M. · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Toxicology · Toxicology and Applied Pharmacology · azoxymethane · quercetin · rutoside · animal experiment · animal model · animal tissue · article · body weight · carcinogenesis · colorectal cancer · diet supplementation · drug effect · incidence · male · nonhuman · rat · survival · Animals · Azoxymethane · beta Catenin · Body Weight · Cell Proliferation · Colorectal Neoplasms · Dietary Supplements · Male · Precancerous Conditions · Quercetin · Rats · Rats, Inbred F344 · Rutin
[Abstract]

9 Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis
article 2008    
Author: Dihal, A.A. · Woude, H. van der · Hendriksen, P.J.M. · Charif, H. · Dekker, L.J. · IJsselstijn, L. · Boer, V.C.J. de · Alink, G.M. · Burgers, P.C. · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Biomarker · Colorectal cancer · Quercetin · Transcriptomics · fatty acid · glutathione peroxidase 2 · heat shock protein · mitogen activated protein kinase · peroxisome proliferator activated receptor alpha · quercetin · transcriptome · animal experiment · animal model · article · cancer prevention · cell cycle · colon mucosa · colorectal cancer · controlled study · down regulation · energy metabolism · Fischer 344 rat · gene expression · gene targeting · genetic analysis · glycolysis · lipid degradation · male · nonhuman · nucleotide sequence · priority journal · proteomics · rat · statistical significance · tumor biopsy · Animals · Colon · Colorectal Neoplasms · Diet · Down-Regulation · Fatty Acids · Gene Expression Profiling · Glycolysis · Intestinal Mucosa · Male · Mitochondria · Proteome · Quercetin · Rats · Rats, Inbred F344 · Rattus
[Abstract]

10 Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro
article 2005    
Author: Erk, M.J. van · Roepman, P. · Lende, T.R. van der · Stierum, R.H. · Aarts, J.M.M.J.G. · Bladeren, P.J. van · Ommen, B. van
Keywords: Health Biology · Biomedical Research · (anti-)carcinogenic mechanisms · Caco-2 · Cell proliferation · Gene expression · Quercetin · beta catenin · mitogen activated protein kinase · quercetin · T cell factor protein · antineoplastic activity · apoptosis · article · cancer cell · cell adhesion · cell cycle · cell cycle G1 phase · cell differentiation · cell interaction · cell proliferation · cell strain CACO 2 · cellular distribution · colon carcinoma · controlled study · DNA microarray · down regulation · drug activity · energy metabolism · gene expression · genetic analysis · human · human cell · in vitro study · nucleotide sequence · oncogene · signal transduction · tumor suppressor gene · unindexed sequence · upregulation · Antineoplastic Agents · Apoptosis · Caco-2 Cells · Cell Cycle · Cell Division · Colonic Neoplasms · Dose-Response Relationship, Drug · Gene Expression · Gene Expression Profiling · Gene Expression Regulation · Humans · Quercetin
[Abstract]

11 Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models
article 2011    
Author: Kleemann, R. · Verschuren, L. · Morrison, M. · Zadelaar, A.S.M. · Erk, M.J. van · Wielinga, P.Y. · Kooistra, T.
Keywords: Nutrition · Anti-inflammatory · Atherosclerosis · Cholesterol · CRP · Inflammation · Polyphenol · Proliferation · Quercetin · C reactive protein · endothelial leukocyte adhesion molecule 1 · fibrinogen · immunoglobulin enhancer binding protein · quercetin · vascular cell adhesion molecule 1 · animal experiment · animal model · antiinflammatory activity · article · atherosclerosis · cardiovascular risk · controlled study · drug activity · drug blood level · drug effect · endothelium cell · human · human cell · inflammation · liver cell · male · mouse · nonhuman · priority journal · protein expression · risk factor · transgenic mouse · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

12 Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures
article 1999    
Author: Berg, R. van den · Haenen, G.R.M.M. · Berg, H. van den · Bast, A.
Keywords: Toxicology · ABTS · Antioxidant capacity · Antioxidants · TEAC · 2,2' azobis(2 amidinopropane) · Alpha tocopherol · Ascorbic acid · Aurantiin · Beta carotene · Cryptoxanthin · Dehydroascorbic acid · Free radical · Hesperidin · Lycopene · Narirutin · Quercetin · Trolox c · Unclassified drug · Zeaxanthin · Antioxidant activity · Chemical modification · Chemical reaction kinetics · Controlled study · Oxidative stress · Screening · Technique
[Abstract]

13 The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells
article 2004    
Author: Verbeek, R. · Plomp, A.C. · Tol, E.A.F. van · Noort, J.M. van
Keywords: Apigenin · Autoimmune · EAE · experimental autoimmune encephalomyelitis · Flavonoids · IFN · IL · interferon · interleukin · Luteolin · MS · multiple sclerosis · PLP · proteolipid protein · T cells · crystallin · gamma interferon · morin · proteolipid protein · quercetin · animal cell · antigen specificity · autoimmunity · cell proliferation · cellular immunity · controlled study · cytokine production · drug efficacy · drug inhibition · evaluation · female · human cell · mouse · multiple sclerosis · nonhuman · Animals · Apigenin · Cell Survival · Dose-Response Relationship, Drug · Flavonoids · Humans · Interferon Type II · Luteolin · Lymphokines · Mice · T-Lymphocytes
[Abstract]

14 An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers
article 2006    
Author: Schutte, M.E. · Freidig, A.P. · Sandt, J.J.M. van de · Alink, G.M. · Rietjens, I.M.C.M. · Groten, J.P.
Keywords: Biology · Biomedical Research · ABC transporter · Caco-2 · Flavonoid · Heterocyclic amine · In silico · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · breast cancer resistance protein · chrysoeriol · elacridar · flavone · flavonoid · kaempferol · luteolin · morin · multidrug resistance protein · myricetin · naringenin · quercetin · robinetin · taxifolin · unclassified drug · verlukast · absorption · apical membrane · article · cell strain CACO 2 · computer model · controlled study · drug effect · human · human cell · Acridines · ATP-Binding Cassette Transporters · Biological Transport, Active · Caco-2 Cells · Carcinogens · Cell Membrane Permeability · Diffusion · Dose-Response Relationship, Drug · Flavanones · Flavonoids · Humans · Imidazoles · Intestinal Absorption · Intestinal Mucosa · Kinetics · Membrane Transport Proteins · Models, Biological · Multidrug Resistance-Associated Proteins · Neoplasm Proteins · P-Glycoprotein · Propionates · Quinolines · Reproducibility of Results · Tetrahydroisoquinolines
[Abstract]

15 Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
article 2005    
Author: Zanden, J.J. van · Wortelboer, H.M. · Bijlsma, S. · Punt, A. · Usta, M. · Bladeren, P.J.V. · Rietjens, I.M.C.M. · Cnubben, N.H.P.
Keywords: Nutrition Pharmacology · Analytical research · Calcein · Flavonoids · MRP1 · MRP2 · QSAR · 3 hydroxyflavone · 3' hydroxyflavone · 3',4' dihydroxyflavone · 3,3' dihydroxyflavone · 3,3',4' trihydroxyflavone · 4' hydroxyflavone · 5,7,3',4' tetramethoxyflavone · acacetin · apigenin · baicalein · catechin · chrysin · fisetin · flavone · flavonoid · galangin · kaempferide · kaempferol · luteolin · morin · multidrug resistance protein 1 · multidrug resistance protein 2 · myricetin · naringenin · protein inhibitor · quercetin · robinetin · taxifolin · unclassified drug · unindexed drug · valspodar · verlukast · animal cell · article · cell kinetics · cell transport · controlled study · drug effect · drug inhibition · drug potency · drug selectivity · genetic transfection · IC 50 · nonhuman · priority journal · protein analysis · quantitative structure activity relation · Animals · Cell Line · Dogs · Flavonoids · Fluoresceins · Membrane Transport Modulators · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Quantitative Structure-Activity Relationship
[Abstract]

16 Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells
article 2004    
Author: Zanden, J.J. van · Geraets, L. · Wortelboer, H.M. · Bladeren, P.J. van · Rietjens, I.M.C.M. · Cnubben, N.H.P.
Keywords: Biology Toxicology · Physiological Sciences · 1-chloro-2,4-dinitrobenzene · 50% inhibition concentration · CDNB · DNP-SG · Glutathione · Glutathione conjugate · Glutathione S-transferase · GS-X · GSH · GST · IC50 · MRP · Multidrug resistance associated protein · P-gp · S-(2,4-dinitrophenyl)glutathione · 3',4' dihydroxyflavone · carbon · catechin · catechol derivative · eriodictyol · flavanoid · flavone derivative · galanin · glutathione transferase · hydroxyl group · kaempferol · luteolin · morin · multidrug resistance protein 1 · multidrug resistance protein 2 · myricetin · quercetin · taxifolin · unclassified drug · animal cell · article · breast cancer · cell strain MCF 7 · chemical bond · controlled study · drug activity · drug potency · enzyme activity · enzyme inhibition · genetic transfection · human · human cell · IC 50 · lipophilicity · nonhuman · priority journal · structure activity relation · toxicokinetics · Biological Transport · Breast Neoplasms · Carrier Proteins · Drug Resistance, Multiple · Drug Resistance, Neoplasm · Flavonoids · Glutathione · Glutathione S-Transferase pi · Glutathione Transferase · Humans · Isoenzymes · Membrane Transport Modulators · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Structure-Activity Relationship · Tumor Cells, Cultured
[Abstract]

17 Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity
article 2006    
Author: Boerboom, A.M.J.F. · Vermeulen, M. · Woude, H. van der · Bremer, B.I. · Lee-Hilz, Y.Y. · Kampman, E. · Bladeren, P.J. van · Rietjens, I.M.C.M. · Aarts, J.M.M.J.G.
Keywords: Biology · Benzyl isothiocyanate · Fisetin · Glutathione transferase · Kaempferol · Luteolin · Myricetin · Quercetin · Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone) · Taxifolin · Tert butylhydroquinone · Animal cell · Antioxidant activity · Cancer cell culture · Cancer screening · Chemoprophylaxis · Controlled study · Drug potency · Drug structure · Electrophile responsive element mediated gene · Enzyme induction · Gene · Gene activation · Gene expression · Gene induction · Genetic transcription · Human cell · Molecular interaction · Mouse · Nonhuman · Reporter gene · Screening test · Stereospecificity · Structure activity relation · Tandem repeat · Transcription initiation · Validation study · Animals · Base Sequence · Cell Line · DNA Primers · Enzyme Induction · Flavonoids · Gene Expression · Genes, Reporter · Humans · Luciferases · Mice · Plasmids · Structure-Activity Relationship · Transcription, Genetic · Benzyl isothiocyanate · Electrophile-responsive element (EpRE) · Hepa-1c1c7 cells · Stable luciferase reporter cell lines · Transient transfection
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 17 of 17 found. | Sort by date