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Showing 1 to 11 of 11 found. | Sort by date

1 Relative absorption and dermal loading of chemical substances : Consequences for risk assessment (Extended Abstract)
article 2007    
Author: Buist, H.E. · Schaafsma, G. · Sandt, J.J.M. van de
Keywords: Biology · Dermal absorption · Dermal loading · Risk assessment · Skin irritation · In vitro · In vivo · Food and Nutrition · Healthy Living

2 The use of human keratinocytes and human skin models for predicting skin irritation: The report and recommendations of ECVAM Workshop 38
article 1999    
Author: Sandt, J. van de · Roguet, R. · Cohen, C. · Esdaile, D. · Ponec, M. · Corsini, E. · Barker, C. · Fusenig, N. · Liebsch, M. · Benford, D. · Brugerolle de · Franissinette, A. de · Fartasch, M.
Keywords: Nutrition · Irritant agent · Erythema · Experimental model · Human · Human cell · Keratinocyte · Priority journal · Skin edema · Skin function · Skin irritation · Skin sensitivity · Stratum corneum

3 Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration
article 2006    
Author: Jacobs, J.J.L. · Lehé, C.L. · Hasegawa, H. · Elliott, G.R. · Das, P.K.
Keywords: Contact allergy · Langerhans cell · Maturation · Migration · Skin irritation · CD83 antigen · Chemokine receptor CCR7 · Contact allergen · Irritant agent · T6 antigen · Article · Cell count · Cell maturation · Cell migration · Contact allergy · Contact sensitization · Controlled study · Dendritic cell · Explant · Human · Human tissue · Hypersensitivity reaction · Immunohistochemistry · Immunopathology · Langerhans cell · Lymph node · Quantitative analysis · Skin allergy · Skin culture · Skin irritation · Allergens · Cell Differentiation · Cell Movement · Dermatitis, Contact · Dermatitis, Occupational · Female · Humans · Irritants · Langerhans Cells · Lymph Nodes · Skin · Skin Irritancy Tests · Tissue Culture Techniques
[Abstract]

4 Relative absorption and dermal loading of chemical substances: Consequences for risk assessment
article 2009    
Author: Buist, H.E. · Schaafsma, G. · Sandt, J.J.M. van de
Keywords: Chemistry · Food and Chemical Risk Analysis · Dermal absorption · Dermal loading · In vitro · In vivo · Risk assessment · Skin irritation · 1 methyl 2 pyrrolidinone · 2 ethoxyethanol · aminolevulinic acid · aminolevulinic acid hexyl ester · aminolevulinic acid methyl ester · atrazine · azinphos methyl · benzo[a]pyrene · benzoic acid · catechol · chemical compound · disulfoton · flurbiprofen · hexachlorobenzene · hydrocortisone · ibuprofen · iprodione · malathion · mevinphos · naloxone · parathion · pentachlorophenol · pesticide · phosmet · pyrene · testosterone · triclosan · trimethylamine · volatile agent · zinc chloride · article · health hazard · human · in vitro study · in vivo study · molecular weight · nonhuman · priority journal · risk assessment · skin absorption · skin irritation
[Abstract]

5 A Toolkit for Dermal Risk Assessment: Toxicological Approach for Hazard Characterization
article 2003    
Author: Schuhmacher-Wolz, U. · Kalberlah, F. · Oppl, R. · Hemmen, J.J. van
Keywords: Chemistry Health · Food and Chemical Risk Analysis · Dermal · Exposure · Hazard assessment · Occupational · Hazardous materials · Health risks · Risk assessment · Skin · Toxicity · Intrinsic toxicity (IT) scores · Occupational risks · Controlled study · Drowsiness · Hazard assessment · Health hazard · Liver injury · Occupational exposure · Occupational health · Skin defect · Skin irritation · Skin penetration · Hazardous Substances · Humans · Models, Theoretical · Occupational Exposure · Skin Absorption
[Abstract]

6 Implementation and evaluation of the fluorescent tracer technique in greenhouse exposure studies
article 1998    
Author: Bierman, E.P.B. · Brouwer, D.H. · Hemmen, J.J. van
Keywords: Nutrition · Air quality · Greenhouses · Health hazards · Industrial hygiene · Pesticides · Risk assessment · Dermal exposure · Fluorescent tracer technique · Occupational risks · Fluorescent dye · Propoxur · Tinopal · Tracer · Unclassified drug · Agricultural worker · Fluorescence · Greenhouse effect · Human · Image analysis · Occupational hazard · Priority journal · Protective clothing · Risk assessment · Skin irritation · Agriculture · Fluorescence · Humans · Image Processing, Computer-Assisted · Occupational Exposure · Skin
[Abstract]

7 Safety evaluation of β-glucanase derived from Trichoderma reesei: Summary of toxicological data
article 1995    
Author: Coenen, T.M.M. · Schoenmakers, A.C.M. · Verhagen, H.
Keywords: Toxicology · barlican · beta glucan hydrolase · unclassified drug · animal experiment · article · chicken · chronic toxicity · controlled study · eye irritation · female · guinea pig · male · mutagenicity · nonhuman · rabbit · rat · skin irritation · skin sensitization · Administration, Oral · Animal · Animal Feed · beta-Glucosidase · Biological Products · Chickens · CHO Cells · Dermatitis, Contact · Environmental Exposure · Female · Food Additives · Guinea Pigs · Hamsters · Lethal Dose 50 · Male · Mutagenicity Tests · No-Observed-Adverse-Effect Level · Rabbits · Rats · Rats, Wistar · Salmonella typhimurium · Toxicity Tests · Trichoderma · Animalia · Cavia porcellus · Gallus gallus · Hypocrea jecorina · Oryctolagus cuniculus · Sus scrofa · Trichoderma
[Abstract]

8 Skin irritation and corrosion
article 2005    
Author: Zuang, V. · Alonso, M.A. · Botham, P.A. · Eskes, C. · Fentem, J. · Liebsch, M. · Sandt, J.J.M. van de
Keywords: Chemistry Safety · Food and Chemical Risk Analysis · cosmetic · acute toxicity · animal testing alternative · cell growth · cell viability · chemical structure · corrosion · electric resistance · explant · human · in vitro study · model · pH measurement · priority journal · reproducibility · review · safety · skin culture · skin irritation · skin water loss · standardization · toxicity testing · validation process · Animal Testing Alternatives · Animals · Cell Survival · Consumer Product Safety · Cosmetics · Endpoint Determination · European Union · Humans · Irritants · Organ Culture Techniques · Quantitative Structure-Activity Relationship · Skin · Skin Irritancy Tests · Swine · Animalia

9 Repeated topical treatment, in contrast to single oral doses, with Vitamin A-containing preparations does not affect plasma concentrations of retinol, retinyl esters or retinoic acids in female subjects of child-bearing age
article 2006    
Author: Nohynek, G.J. · Meuling, W.J.A. · Vaes, W.H.J. · Lawrence, R.S. · Shapiro, S. · Schulte, S. · Steiling, W. · Bausch, J. · Gerber, E. · Sasa, H. · Nau, H.
Keywords: Nutrition · Analytical research · Biomonitoring · CAS 68-26-8 · CAS 79-81-2 · Human subjects · Plasma concentrations · Retinoic acids · Retinol · Retinyl palmitate · Teratogenicity · Topical and oral administration · 4 oxoretinoic acid · oleic acid · retinoic acid · retinol · retinol ester · retinol palmitate · stearic acid · absence of side effects · adult · area under the curve · article · blood sampling · body surface · clinical article · controlled study · dose response · female · human · pregnancy · priority journal · retinol deficiency · skin irritation · statistical analysis · vitamin blood level · Administration, Oral · Administration, Topical · Adult · Cosmetics · Female · Humans · Risk Assessment · Vitamin A
[Abstract]

10 The contact allergen dinitrochlorobenzene (DNCB) and respiratory allergy in the Th2-prone Brown Norway rat
article 2008    
Author: Kuper, C.F. · Stierum, R.H. · Boorsma, A. · Schijf, M.A. · Prinsen, M. · Bruijntjes, J.P. · Bloksma, N. · Arts, J.H.E.
Keywords: Health · Dinitrochlorobenzene · LLNA · MCP-1 · MIP1-beta · Respiratory allergy · Skin allergy · 1 chloro 2,4 dinitrobenzene · CD4 antigen · immunoglobulin G · macrophage inflammatory protein 1beta · monocyte chemotactic protein 1 · monocyte chemotactic protein 3 · thymus and activation regulated chemokine · animal experiment · animal model · animal tissue · article · controlled study · female · lung function · lung lavage · lung parenchyma · male · microarray analysis · nonhuman · Norway · nucleotide sequence · priority journal · rat · respiratory tract allergy · skin allergy · skin irritation · skin sensitization · Th2 cell · upregulation · Administration, Cutaneous · Allergens · Animals · Dermatitis, Allergic Contact · Dinitrochlorobenzene · Female · Immunoglobulin E · Immunoglobulin G · Inhalation Exposure · Irritants · Local Lymph Node Assay · Lung · Lymph Nodes · Male · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Hypersensitivity · Th2 Cells · Animalia · Rattus · Rattus norvegicus
[Abstract]

11 Dose-response relationships and threshold levels in skin and respiratory allergy
article 2006    
Author: Arts, J.H.E. · Mommers, C. · Heer, C.de
Keywords: Health · Toxicology and Applied Pharmacology · Dose-Response · Elicitation · Respiratory Allergy · Sensitization · Skin Allergy · 1 chloro 2,4 dinitrobenzene · 1 fluoro 2,4 dinitrobenzene · acid anhydride · aldehyde · benzocaine · bronopol · chlorocresol · cytokine · dichromate potassium · diethylamine · ethylene · eugenol · formaldehyde · geraniol · glutaraldehyde · immunoglobulin E antibody · isocyanic acid derivative · isoeugenol · kathon cg · linalool · methacrylic acid derivative · myristic acid isopropyl ester · nickel · oxazolone · phthalic anhydride · rubber · subtilisin · toluene diisocyanate · tuberculin · unindexed drug · airway obstruction · analytic method · antigen specificity · CD4+ T lymphocyte · clinical study · concentration (parameters) · Dermatophagoides farinae · Dermatophagoides pteronyssinus · dose response · expiratory flow · exposure · forced expiratory volume · guinea pig · human · hypersensitivity reaction · Langerhans cell · nonhuman · occupational asthma · occupational hazard · respiratory tract allergy · review · safety · sensitivity analysis · skin allergy · skin defect · skin irritation · skin sensitization · skin test · urticaria · Allergens · Animals · Dermatitis, Allergic Contact · Dose-Response Relationship, Drug · Guidelines · Humans · Molecular Weight · No-Observed-Adverse-Effect Level · Occupational Exposure · Respiratory Hypersensitivity · Risk Assessment · Skin Tests · Animalia · Cavia porcellus · Dermatophagoides farinae · Dermatophagoides pteronyssinus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 11 of 11 found. | Sort by date