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1 Fast and accurate method for total 4-desmethyl sterol(s) content in spreads, fat-blends and raw materials
article 2002    
Author: Duchateau, G.S.M.J.E. · Bauer-Plank, C.G. · Louter, A.J.H. · Ham, M. van der · Boerma, J.A. · Rooijen, J.J.M. van · Zandbelt, P.A.
Keywords: Nutrition · Alcohols · Esters · Extraction · Fatty acids · Gas chromatography · Quality control · Raw materials · Saponification · Standards · Desmethyl sterol · Fat blends · Internal standard · Plant sterols · Vegetable oil table spreads · Vegetable oils
[Abstract]

2 On the mode of action of 3 phenylindole towards Aspergillus niger
article 1976    
Author: Hoppe, H.H. · Kerkenaar, A. · Kaars Sypesteyn, A.
Keywords: Biology · Ergosterol · Phospholipid · Radioisotope · Sterol · 3 phenylindole · Aspergillus niger · Drug mechanism · Drug sensitivity · Fungus · Microorganism · Phosphoric acid p 31 · Theoretical study
[Abstract]

3 Different effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on sterol synthesis in various human cell types
article 1995    
Author: Vliet, A.K. van · Thiel, G.C.F. van · Huisman, R.H. · Moshage, H. · Yap, S.H. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitor · Human cell · Lovastatin · Pravastatin · Simvastatin · Sterol synthesis · Transport · hydroxymethylglutaryl coenzyme a reductase inhibitor · mevinolin · pravastatin · simvastatin · controlled study · human · human cell · liver cell · priority journal · sterol synthesis · Blotting, Northern · Cells, Cultured · Endothelium, Vascular · Female · Granulosa Cells · Human · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Liver · Lovastatin · Pigment Epithelium of Eye · RNA, Messenger · Simvastatin · Sterols · Umbilical Veins
[Abstract]

4 Moderate doses of alcoholic beverages with dinner and postprandial high density lipoprotein composition
article 1998    
Author: Hendriks, H.F.J. · Veenstra, J. · Tol, A. van · Groener, J.E.M. · Schaafsma, G.
Keywords: Nutrition · Alcohol Drinking · Apolipoproteins · Area Under Curve · Carrier Proteins · Cholesterol · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Ethanol · Female · Glycoproteins · Humans · Male · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipids · Postprandial Period · Triglycerides
[Abstract]

5 Acyl-CoA:Cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-leiden mice
article 2001    
Author: Delsing, D.J.M. · Offerman, E.H. · Duyvenvoorde, W. van · Boom, H. van der · Wit, E.C.M. de · Gijbels, M.J.J. · Laarse, A. van der · Jukema, J.W. · Havekes, L.M. · Princen, H.M.G.
Keywords: Biology · Acetates · Animals · Anticholesteremic Agents · Aortic Valve · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Body Weight · Cell Adhesion · Cell Line · Cholesterol · Diet, Atherogenic · Disease Models, Animal · Eating · Endothelium, Vascular · Female · Heterozygote · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Sterol O-Acyltransferase · Sulfonic Acids
[Abstract]

6 Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7α-hydroxylase in cultured rat hepatocytes and in vivo in the rat
article 1999    
Author: Post, S.M. · Paul Zoeteweij, J. · Bos, M.H.A. · Wit, E.C.M. de · Havinga, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Biology · Acetates · Animals · Anticholesteremic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Enzyme Induction · Enzyme Inhibitors · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Sterol O-Acyltransferase · Sulfonic Acids · Triglycerides
[Abstract]

7 Isolation and molecular characterisation of the gene encoding eburicol 14α-demethylase (CYP51) from Penicillium italicum
article 1996    
Author: Nistelrooy, J.G.M. van · Brink, J.M. van den · Kan, J.A.L. van · Gorcom, R.F.M. van · Waard, M.A. de
Keywords: Biology · 14α-demethylase · Cytochrome P450 · Fungicides · Penicillium italicum · Sterol biosynthesis inhibitors · Cytochrome p450 isoenzyme · Enilconazole · Etaconazole · Fenarimol · Fungicide · Unclassified drug · Article · Controlled study · Gene isolation · Genetic analysis · Molecular cloning · Molecular genetics · Nonhuman · Penicillium · Priority journal · Sterol synthesis · Yeast · Amino Acid Sequence · Base Sequence · Blotting, Northern · Cloning, Molecular · Cytochrome P-450 Enzyme System · DNA Primers · Fungal Proteins · Fungicides, Industrial · Genes, Fungal · Lanosterol · Molecular Sequence Data · Oxidoreductases · Penicillium · Pyrimidines · Restriction Mapping · Sequence Analysis, DNA · Sequence Homology, Amino Acid
[Abstract]

8 Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity
article 2008    
Author: Pols, T.W.H. · Ottenhoff, R. · Vos, M. · Levels, J.H.M. · Quax, P.H.A. · Meijers, J.C.M. · Pannekoek, H. · Groen, A.K. · Vries, C.J.M. de
Keywords: Biology · Lipid metabolism · NR4A nuclear receptors · NR4A1 · Nur77 · SREBP1c · Sterol regulatory element binding protein-1 · ABC transporter · ABC transporter G5 · ABC transporter G8 · acyl coenzyme A desaturase · acyl coenzyme A desaturase 1 · adenovirus vector · fatty acid synthase · glycerol 3 phosphate acyltransferase · low density lipoprotein receptor · nuclear receptor Nur77 · sterol regulatory element binding protein 1c · triacylglycerol · animal experiment · animal tissue · article · controlled study · enzyme activity · enzyme repression · gene expression · genetic analysis · lipid blood level · lipid liver level · lipid metabolism · male · mouse · nonhuman · nucleotide sequence · priority journal · protein expression · protein function · Adenoviridae · Animals · DNA-Binding Proteins · Gene Expression Regulation · Lipid Metabolism · Liver · Male · Mice · Mice, Inbred C57BL · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · Sterol Regulatory Element Binding Protein 1 · Transcription Factors · Triglycerides · Mus
[Abstract]

9 Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9
article 2015    
Author: Tuin, S.J. van der · Kühnast, S. · Berbée, J. · Verschuren, L. · Pieterman, E.J. · Havekes, L.M. · Hoorn, J.W. van der · Rensen, P.C. · Jukema, J.W. · Princen, H.M. · Willems van Dijk, K. · Wang, Y.
Keywords: Health · CETP · Cholesterol · Metabolism · Drug therapy · Hypolipidemic drugs · LDL · Metabolism · Lipids · Lipoproteins · PCSK9 · Anacetrapib · Apolipoprotein B · Cholesterol ester transfer protein · Low density lipoprotein receptor · Proprotein convertase subtilisin kexin type 9 · RNA · Serine proteinase · Sterol regulatory element binding protein 1 · Sterol regulatory element binding protein 2 · Triacylglycerol · Unclassified drug · Very low density lipoprotein cholesterol · Animal experiment · Animal tissue · Atherosclerosis · Cholesterol synthesis · Controlled study · Down regulation · Drug mechanism · Enzyme blood level · Female · Liver · Microarray analysis · Mouse · Nonhuman · Polymerase chain reaction · Protein expression · RNA isolation · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

10 Heterogeneous expression of cholesterol 7α-hydroxylase and sterol 27- hydroxylase genes in the rat liver lobulus
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Mager, W.H. · Moorman, A.F.M. · Boer, P.A.J. de · Scheja, L. · Princen, H.M.G. · Gebhardt, R.
Keywords: Health · 3 hydroxy 3 methylglutaryl coenzyme a · alanine aminotransferase · cholesterol 7alpha monooxygenase · colestipol · glutamate ammonia ligase · glyceraldehyde 3 phosphate dehydrogenase · messenger rna · pyruvate kinase · sterol 27 hydroxylase · unclassified drug · animal cell · animal experiment · bile acid synthesis · controlled study · enterohepatic circulation · enzyme isolation · enzyme localization · gene expression · in situ hybridization · liver metabolism · sterol analysis · Animal · Biological Markers · Blotting, Northern · Cell Separation · Cholesterol 7-alpha-Hydroxylase · Colestipol · Cytochrome P-450 Enzyme System · Gene Expression Regulation, Enzymologic · In Situ Hybridization · Liver · Male · Rats · Rats, Sprague-Dawley · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Tissue Distribution · Transcription, Genetic
[Abstract]

11 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

12 Vastatins have a distinct effect on sterol synthesis and progesterone secretion in human granulosa cells in vitro
article 1996    
Author: Vliet, A.K. van · Thiel, G.C.F. van · Naaktgeboren, N. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitor · Progesterone secretion · Simvastatin · Sterol synthesis · Cholesterol · Low density lipoprotein · Methysticin · Cholesterol synthesis · Controlled study · Human cell · Cells, Cultured · Cholesterol · Culture Media · Enzyme Inhibitors · Female · Follicle Stimulating Hormone · Granulosa Cells · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Luteinizing Hormone · Pravastatin · Progesterone · Simvastatin
[Abstract]

13 Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment
article 1993    
Author: Lombardi, P. · Mulder, M. · Boom, H. van der · Frants, R.R. · Havekes, L.M.
Keywords: Cholesterol acyltransferase · Lipoprotein · Lipoprotein receptor · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Density gradient centrifugation · Endosome · Enzyme activity · Homeostasis · Human cell · Lipid transport · Protein binding · Protein degradation · Biological Transport · Cell Compartmentation · Cell Line · Cholesterol · Endocytosis · Esterification · Human · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Lysosomes · Sterol O-Acyltransferase · Support, Non-U.S. Gov't · Triglycerides
[PDF] [Abstract]

14 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

15 Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin
article 2014    
Author: Kühnast, S. · Hoorn, J.W.A. van der · Pieterman, E.J. · Hoek, A.M. van den · Sasiela, W.J. · Gusarova, V. · Peyman, A. · Schäfer, H.L. · Schwahn, U. · Jukema, J.W. · Princen, H.M.G.
Keywords: Biology · 3Leiden.CETP mice · APOE · Atorvastatin · Proprotein convertase subtilisin/kexin type 9 · Alirocumab · Apolipoprotein E · Atorvastatin · Bile acid · Cholesterol · Collagen · Low density lipoprotein receptor · Sterol · Triacylglycerol · Animal experiment · Animal model · Atherosclerosis · Atherosclerotic plaque · Controlled study · Disease severity · Dose response · Drug effect · Drug potentiation · Drug safety · Fat content · Female · Lipid blood level · Monocyte · Monotherapy · Mouse · Nonhuman · Protein degradation · Smooth muscle fiber · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

16 Increased resistance to 14α-demethylase inhibitors (DMIs) in Aspergillus niger by coexpression of the Penicillium italicum eburicol 14α-demethylase (cyp51) and the A. Niger cytochrome P450 reductase (cprA) genes
article 1996    
Author: Brink, H.J.M. van den · Nistelrooy, H.J.G.M. van · Waard, M.A. de · Hondel, C.A.M.J.J. van den · Gorcom, R.F.M. van
Keywords: Biology · Ergosterol · NADPH cytochrome P450 reductase · Sterol 14α-demethylation inhibitors · Drug products · Fungicides · Genes · Demethylase inhibitors (DMI) · Gene encoding · Genetic engineering · Cytochrome p450 reductase · Reduced nicotinamide adenine dinucleotide phosphate ferrihemoprotein reductase · Enzyme synthesis · Fungal genetics · Nonhuman · Penicillium · Priority journal · Aspergillus niger · Cytochrome P-450 Enzyme System · Drug Resistance, Microbial · Enzyme Inhibitors · Gene Expression Regulation, Fungal · NADH, NADPH Oxidoreductases · NADPH-Ferrihemoprotein Reductase · Oxidoreductases · Penicillium · Recombinant Proteins · Transformation, Genetic · Aspergillus niger · Fungi · Penicillium · Penicillium italicum
[Abstract]

17 Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle
article 1996    
Author: Vliet, A.K. van · Nègre-Arrariou, P. · Thiel, G.C.F. van · Bolhuis, P.A. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitors · Human myoblasts · Sterol synthesis · Adenosine triphosphate · Hydroxymethylglutaryl coenzyme a reductase inhibitor · Mevinolin · Mitochondrial enzyme · Cell culture · Cell proliferation · Cell viability · Concentration response · Controlled study · Dna synthesis · Human cell · Human tissue · Muscle biopsy · Myoblast · Myopathy · Skeletal muscle · Acetic Acid · Adenosine Triphosphate · Anticholesteremic Agents · Cell Division · Cell Survival · Cells, Cultured · DNA · Enzyme Inhibitors · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Mitochondria · Muscle, Skeletal · Oxidoreductases · Pravastatin · Simvastatin · Sterols
[Abstract]

18 Differential effects of 17α-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat
article 1999    
Author: Koopen, N.R. · Post, S.M. · Wolters, H. · Havinga, R. · Stellaard, F. · Boverhof, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Δ-<sup>22</sup>-β-muricholate · Bile · Cholestasis · Cholesterol-7α- hydroxylase · Enterohepatic circulation · Estrogens · Sterol-27-hydroxylase · Wistar rat · Animals · Aryl Hydrocarbon Hydroxylases · Bile Acids and Salts · Chenodeoxycholic Acid · Cholates · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Enterohepatic Circulation · Ethinyl Estradiol · Hydrogen-Ion Concentration · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Steroid 12-alpha-Hydroxylase · Steroid Hydroxylases
[PDF] [Abstract]

19 Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Lehmann, E.M. · Meijer, P. · Mager, W.H. · Princen, H.M.G.
Keywords: Biology · cholesterol 7alpha monooxygenase · insulin · oxygenase · sterol 27 hydroxylase · unclassified drug · animal cell · article · bile acid synthesis · controlled study · down regulation · enzyme activity · gene expression regulation · hormone action · liver cell culture · nonhuman · transcription regulation · Animal · Bile Acids and Salts · Cells, Cultured · Chloramphenicol O-Acetyltransferase · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Down-Regulation · Gene Expression Regulation, Enzymologic · Insulin · Liver · Male · Membrane Glycoproteins · Nuclear Proteins · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Transcription, Genetic · Transfection
[Abstract]

20 Bromobenzene-induced hepatotoxicity at the transcriptome level
article 2004    
Author: Heijne, W.H.M. · Slitt, A.L. · Bladeren, P.J. van · Groten, J.P. · Klaassen, C.D. · Stierum, R.H. · Ommen, B. van
Keywords: Biology Toxicology · Physiological Sciences · Bromobenzene · cDNA microarray · Hepatotoxicity · Rat · Toxicogenomics · Transcriptomics · Bromobenzene · Cholesterol · Complementary DNA · Cytochrome P450 4A · Fatty acid · Glutathione · Messenger RNA · Metallothionein · Protein · Sterol · Acute phase response · Animal experiment · Animal model · Animal tissue · Cell communication · Cholesterol metabolism · Concentration response · Controlled study · Cytoskeleton · DNA determination · DNA microarray · DNA responsive element · Drug metabolism · Electron · Fatty acid metabolism · Gene amplification · Gene expression profiling · Gene rearrangement · Liver toxicity · Nonhuman · Nucleotide sequence · Oxidative stress · Protein depletion · Protein metabolism · Protein synthesis · Rat · Signal transduction · Transcription regulation · Animals · Bromobenzenes · Gene Expression Profiling · Gene Expression Regulation · Glutathione · Hepatitis, Toxic · Liver · Male · Microarray Analysis · Oligonucleotide Array Sequence Analysis · Rats · Rats, Inbred Strains · Time Factors · Transcription, Genetic
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date