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1 Structure-function relationship of the human antimicrobial peptide LL-37 and LL-37 fragments in the modulation of TLR responses
article 2009    
Author: Molhoek, E.M. · Hertog, A.L. den · Vries, A.M.B.C. de · Nazmi, K. · Veerman, E.C.I. · Hartgers, F.C. · Yazdanbakhsh, M. · Bikker, F.J. · Kleij, D. van der
Keywords: Chemistry · Cathelicidins · Immunomodulation · MAP kinases · Physico-chemical properties · Bacterium lipopolysaccharide · Cathelicidin antimicrobial peptide LL 37 · Cytokine · Mitogen activated protein kinase · Mitogen activated protein kinase p38 · Toll like receptor · Toll like receptor 1 · Toll like receptor 2 · Toll like receptor 4 · Toll like receptor 5 · Toll like receptor 6 · Toll like receptor 7 · Toll like receptor 8 · Antiinflammatory activity · Antimicrobial activity · Article · Cytokine release · Human · Human cell · Hydrophobicity · Immunomodulation · Peripheral blood mononuclear cell · Priority journal · Protein phosphorylation · Structure activity relation · Amino Acid Sequence · Antimicrobial Cationic Peptides · Cells, Cultured · Chromatography, High Pressure Liquid · Circular Dichroism · Humans · Ligands · Molecular Sequence Data · Signal Transduction · Structure-Activity Relationship · Toll-Like Receptors · Bacteria (microorganisms)
[Abstract]

2 Differentiation of primary adult microglia alters their response to TLR8-mediated activation but not their capacity as APC
article 2007    
Author: Zuiderwijk-Sick, E.A. · Putten, C. van der · Bsibsi, M. · Deuzing, I.P. · Boer, W. de · Persoon-Deen, C. · Kondova, I. · Boven, L.A. · Noort, J.M. van · Hart, B.A. 't · Amor, S. · Bajramovic, J.J.
Keywords: Health · Biomedical Research · Cell differentiation · Innate immune system · Monocytes/macrophages · Neuroimmunology · messenger RNA · toll like receptor 1 · toll like receptor 2 · toll like receptor 3 · toll like receptor 4 · toll like receptor 5 · toll like receptor 6 · toll like receptor 7 · toll like receptor 8 · toll like receptor 9 · transfer RNA · animal cell · antigen expression · antigen presentation · antigen presenting cell · article · cell differentiation · cell ultrastructure · colony forming unit GM · colony forming unit M · controlled study · cytokine production · innate immunity · microglia · mixed lymphocyte reaction · neuroimmunology · nonhuman · phagocyte · phenotype · priority journal · rhesus monkey · Animals · Antigen-Presenting Cells · Bone Marrow Cells · Cell Differentiation · Cell Lineage · Cell Proliferation · Cell Separation · Enzyme-Linked Immunosorbent Assay · Female · Flow Cytometry · Granulocyte-Macrophage Colony-Stimulating Factor · Lymphocyte Culture Test, Mixed · Macaca mulatta · Macrophage Activation · Macrophage Colony-Stimulating Factor · Male · Microglia · Phagocytosis · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Toll-Like Receptor 8
[Abstract]

3 Activation of toll-like receptors and dendritic cells by a broad range of bacterial molecules
article 2009    
Author: Boele, L.C.L. · Bajramovic, J.J. · Vries, A.M.M.B.C. de · Voskamp-Visser, I.A.I. · Kaman, W.E. · Kleij, D. van der
Keywords: Biology · Bacteria · Cytokines · Dendritic cell · Pathogens · Toll-like receptor · toll like receptor · toll like receptor 2 · toll like receptor 4 · toll like receptor 5 · article · cell maturation · cell polarity · controlled study · cytokine production · dendritic cell · genetic transfection · human · human cell · priority journal · Staphylococcus aureus · T lymphocyte · Vibrio cholerae · Yersinia pestis · Yersinia pseudotuberculosis · Animals · Antigens, CD · Bacteria · Biological Markers · Cell Line · Coculture Techniques · Cytokines · Dendritic Cells · HLA-DR Antigens · Humans · Ligands · Protein Isoforms · T-Lymphocytes · Toll-Like Receptors · Ultraviolet Rays · Bacteria (microorganisms) · Negibacteria · Posibacteria
[Abstract]

4 Innate, adaptive and regulatory responses in schistosomiasis: Relationship to allergy
article 2006    
Author: Hartgers, F.C. · Smits, H.H. · Kleij, D. van der · Yazdanbakhsh, M.
Keywords: Anthelmintic agent · Immunoglobulin G4 · Intercellular adhesion molecule 3 · Interleukin 13 receptor · Pattern recognition receptor · STAT1 protein · Tetanus toxoid · Toll like receptor 1 · Toll like receptor 3 · Toll like receptor 5 · Toll like receptor 6 · Toll like receptor 7 · Toll like receptor 8 · Allergy · Antibody production · Antigen specificity · Atopy · Brugia malayi · CD4+ CD25+ T lymphocyte · Cellular immunity · Chronic disease · Clonal anergy · Cross tolerance · Dendritic cell · Down regulation · Endemic disease · Helicobacter pylori · Helminthiasis · Human · Immune deficiency · Immune response · Immunoregulation · Inflammation · Innate immunity · Lymphocyte proliferation · Mast cell degranulation · Molecular interaction · Nippostrongylus brasiliensis · Nonhuman · Regulatory T lymphocyte · Review · Schistosoma · Schistosoma hematobium · Schistosoma mansoni · Schistosomiasis · Sensitization · T lymphocyte activation · T lymphocyte subpopulation · Tetanus · Th1 cell · Th2 cell · Upregulation · Animals · Chronic Disease · Hypersensitivity · Immune Tolerance · Immunity, Natural · Interleukin 13, 148157-34-0 · Tetanus toxoid, 57425-69-1, 93384-51-1 · Toll like receptor 2, 203811-81-8 · Toll like receptor 4, 203811-83-0 · Toll like receptor 9, 352486-49-8, 390883-32-6 · Toll like receptor, 409141-78-2
[Abstract]

5 Toll-like receptors as targets for inflammation, development and repair in the central nervous system
article 2007    
Author: Noort, J.M. van
Keywords: Biomedical Research · Astrocyte · CNS · Inflammation · Microglia · Tissue repair · Toll-like receptor · Animals · Central Nervous System · Central Nervous System Diseases · Humans · Inflammation · Toll-Like Receptors
[Abstract]

6 Immunologic activity of schistosomal and bacterial TLR2 ligands in Gabonese children
article 2008    
Author: Retra, K. · Riet, E. van · Adegnika, A.A. · Everts, B. · Geest, S. van · Kremsner, P.G. · Hellemond, J.J. van · Kleij, D. van der · Tielens, A.G.M. · Yazdanbakhsh, M.
Keywords: Biology · Lysophosphatidylserine · MALP-2 · Monoacylglycerophosphoserine · PAM 3CSK4 · Schistosoma mansoni · Th1 · Th2 · Toll-like receptor · Interleukin 10 · Ligand · Lysophosphatidylserine · Phosphatidylserine · Toll like receptor 2 · Tumor necrosis factor alpha · Adolescent · Blood culture · Child · Clinical article · Endemic disease · Female · Humans · Immune system · Immunoreactivity · Immunoregulation · Lipid analysis · Male · Schistosoma · Schistosomiasis · Statistical analysis · Animals · Cell Line · Child, Preschool · Cytokines · Gabon · Lysophospholipids · Oligopeptides · Peptides · Schistosoma mansoni · Toll-Like Receptor 2 · Bacteria (microorganisms) · Schistosoma mansoni · Toll like receptor 2, 203811-81-8 · Cytokines · Lysophosphatidylserine · Macrophage stimulatory lipopeptide 2 · Pam(3)CSK(4) peptide · Life · CBRN - CBRN Protection · ELSS - Earth, Life and Social Sciences
[Abstract]

7 Broad expression of Toll-like receptors in the human central nervous system
article 2002    
Author: Bsibsi, M. · Ravid, R. · Gveric, D. · Noort, J.M. van
Keywords: Health · Central nervous system · Oligodendrocytes · Toll-like receptors · Toll like receptor · Unclassified drug · Alzheimer disease · Cell vacuole · Controlled study · Human tissue · Immunocytochemistry · Parkinson disease · Pick presenile dementia · Protein expression · Aged · Aged, 80 and over · Astrocytes · Cells, Cultured · Central Nervous System · Central Nervous System Infections · Drosophila Proteins · Encephalitis · Female · Gene Expression Regulation · Humans · Immune System · Immunohistochemistry · Male · Membrane Glycoproteins · Microglia · Middle Aged · Multiple Sclerosis · Neuroglia · Oligodendroglia · Receptors, Cell Surface · RNA, Messenger · Toll-Like Receptor 2 · Toll-Like Receptor 3 · Toll-Like Receptor 4 · Toll-Like Receptors
[Abstract]

8 Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
article 2008    
Author: Timmers, L. · Sluijter, J.P.G. · Keulen, J.K. van · Hoefer, I.E. · Nederhoff, M.G.J. · Goumans, M.J. · Doevendans, P.A. · Echteld, C.J.A. van · Joles, J.A. · Quax, P.H. · Piek, J.J. · Pasterkamp, G. · Kleijn, D.P.V. de
Keywords: Biology · Biomedical Research · Animals · Cytokines · Gene Expression Regulation · Heart · Heart Failure · Mice · Myocardial Infarction · Stroke Volume · Toll-Like Receptor 4 · Ventricular Remodeling
[PDF]

9 The microtubule regulator stathmin is an endogenous protein agonist for TLR3.
article 2010    
Author: Bsibsi, M. · Bajramovic, J.J. · Vogt, M.H. · Duijvenvoorden, E. van · Baghat, A. · Persoon-Deen, C. · Tielen, F. · Verbeek, R. · Huitinga, I. · Ryffel, B. · Kros, A. · Gerritsen, W.H. · Amor, S. · Noort, J.M. van
Keywords: Biology · Biomedical Research · small interfering RNA · stathmin · TLR3 protein, human · toll like receptor 3 · animal · article · astrocyte · brain · gene library · human · immunology · metabolism · microglia · microtubule · mouse · nerve cell · signal transduction · Western blotting · Animals · Astrocytes · Blotting, Western · Brain · Gene Library · Humans · Mice · Microglia · Microtubules · Neurons · RNA, Small Interfering · Signal Transduction · Stathmin · Toll-Like Receptor 3
[Abstract]

10 RP105 deficiency aggravates cardiac dysfunction after myocardial infarction in mice
article 2014    
Author: Louwe, M.C. · Karper, J.C. · Vries, M.R. de · Nossent, A.Y. · Bastiaansen, A.J.N.M. · Hoorn, J.W.A. van der · Willems Van Dijk, K. · Rensen, P.C.N. · Steendijk, P. · Smit, J.W.A. · Quax, P.H.A.
Keywords: Biology · Heart function · Myocardial infarction · Pressure-volume loops · RP105 · Toll-like receptor 4 · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

11 P430RP105 deficiency aggravates cardiac dysfunction after myocardial infarction in mice
article 2014    
Author: Louwe, M.C. · Karper, J.C. · Vries, M.R. de · Bastiaansen, A.J.N.M. · Hoorn, J.W.A. van der · Willems Van Dijk, K. · Rensen, P.C.N. · Steendijk, P. · Smit, J.W.A. · Quax, P.H.A.
Keywords: Biology · Heart function · Myocardial infarction · Pressure-volume loops · RP105 · Toll-like receptor 4 · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: Molecular correlates for Th1/Th2 polarization
article 2009    
Author: Riet, E. van · Everts, B. · Retra, K. · Phylipsen, M. · Hellemond, J.J. van · Tielens, A.G.M. · Kleij, D. van der · Hartgers, F.C. · Yazdanbakhsh, M.
Keywords: Biology · messenger RNA · mitogen activated protein kinase p38 · Notch4 receptor · phospholipid · protein c fos · toll like receptor 2 · toll like receptor 4 · bacterial antigen · mitogen activated protein kinase · parasite antigen · TLR2 protein, human · TLR4 protein, human · article · Ascaris lumbricoides · controlled study · dendritic cell · enzyme activation · Escherichia coli · gene activity · gene expression profiling · gene expression regulation · human · human cell · Listeria monocytogenes · lymphocyte function · nonhuman · polarization · Schistosoma mansoni · signal transduction · T lymphocyte activation · Th1 cell · Th2 cell · animal · cytology · gene expression · immunology · metabolism · microbiology · monocyte · reverse transcription polymerase chain reaction · Animals · Antigens, Bacterial · Antigens, Helminth · Ascaris lumbricoides · Dendritic Cells · Enzyme Activation · Escherichia coli · Gene Expression · Gene Expression Profiling · Humans · Listeria monocytogenes · Mitogen-Activated Protein Kinases · Monocytes · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Schistosoma mansoni · Signal Transduction · Th1 Cells · Th2 Cells · Toll-Like Receptor 2 · Toll-Like Receptor 4
[Abstract]

13 Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators
article 2006    
Author: Bsibsi, M. · Persoon-Deen, C. · Verwer, R.W.H. · Meeuwsen, S. · Ravid, R. · Noort, J.M. van
Keywords: Biology · Biomedical Research · Astrocytes · Inflammation · Neuroprotection · Toll-like receptors · interleukin 10 · interleukin 12 · interleukin 23 · interleukin 9 · lipopolysaccharide · polyinosinic polycytidylic acid · protein p40 · cell differentiation · cell growth · cell migration · controlled study · gene induction · genetic analysis · human cell · human tissue · nerve cell · neuroprotection · nucleotide sequence · oxidative stress · protein expression · protein induction · unindexed sequence · Aged · Aged, 80 and over · Astrocytes · Cell Survival · Cells, Cultured · Cytokines · Cytoprotection · Down-Regulation · Encephalitis · Endothelial Cells · Female · Gliosis · Growth Inhibitors · Growth Substances · Humans · Interleukins · Male · Neuroprotective Agents · Toll-Like Receptor 3 · Toll-Like Receptor 4 · Up-Regulation
[Abstract]

14 Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix
article 2010    
Author: Berbé, J.F.P. · Coomans, C.P. · Westerterp, M. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Endotoxins · Inflammation · Mice · Peptide · Tnfα · Apolipoprotein C1 · CD14 antigen · Lipopolysaccharide · Lipopolysaccharide binding protein · Toll like receptor 4 · Tumor necrosis factor alpha · Amino terminal sequence · Animal cell · Animal experiment · Carboxy terminal sequence · Controlled study · Cytokine release · Electrophoretic mobility · Mouse · Nonhuman · Peritoneum macrophage · Plasma clearance · Signal transduction
[PDF] [Abstract]

15 Prolonged in vivo gene silencing by electroporation-mediated plasmid delivery of small interfering RNA
article 2007    
Author: Eefting, D. · Grimbergen, J.M. · Vries, M.R. de · Weel, V. van · Kaijzel, E.L. · Que, I. · Moon, R.T. · Löwik, C.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · double stranded RNA · histidine · luciferase · oligonucleotide · plasmid vector · small interfering RNA · toll like receptor 4 · uridine · animal cell · animal experiment · article · bioluminescence · controlled study · electroporation · gastrocnemius muscle · gene expression · gene function · gene repression · gene silencing · human · human cell · immune response · in vivo gene transfer · in vivo study · male · mouse · nonhuman · nonviral gene delivery system · protein expression · restenosis · RNA interference · transgene · treatment planning · tumor · viral gene delivery system · Animals · Cattle · Cell Line, Transformed · Cell Transformation, Viral · Electroporation · Feasibility Studies · Gene Silencing · Genes, Reporter · Humans · Hypoxanthine Phosphoribosyltransferase · Lipopolysaccharides · Luciferases · Luminescent Measurements · Male · Mice · Mice, Inbred Strains · Muscle, Skeletal · NIH 3T3 Cells · Plasmids · RNA Interference · RNA, Messenger · RNA, Small Interfering · Time Factors · Toll-Like Receptor 4 · Murinae
[Abstract]

16 Identification of soluble CD14 as an endogenous agonist for toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins
article 2007    
Author: Bsibsi, M. · Bajramovic, J.J. · Duijvenvoorden, E. van · Persoon, C. · Ravid, R. · Noort, J.M. van · Vogt, M.H.J.
Keywords: Biomedical Research · CD14 · Functional genomics · Toll-like receptors · CD14 antigen · complementary DNA · interleukin 12p40 · interleukin 1beta · interleukin 6 · interleukin 8 · soluble cd14 antigen · toll like receptor 2 · tumor necrosis factor alpha · animal cell · article · astrocyte · brain tumor · cell stimulation · controlled study · cytokine release · DNA library · gene pool · genetic screening · genetic transfection · genome · human · human cell · human tissue · microglia · nonhuman · priority journal · protein synthesis · receptor upregulation · tumor cell line · Adult · Amino Acid Sequence · Animals · Antigens, CD14 · Astrocytes · Base Sequence · Cells, Cultured · Cercopithecus aethiops · COS Cells · DNA, Complementary · Gene Expression Profiling · Genomic Library · Humans · Interleukin-12 Subunit p40 · Interleukin-6 · Interleukin-8 · Interleukins · Macaca mulatta · Microglia · Molecular Sequence Data · Signal Transduction · Toll-Like Receptor 2
[Abstract]

17 Toll-like receptor 2 activation by β2→1-fructans protects barrier function of t84 human intestinal epithelial cells in a chain length-dependent manner
article 2014    
Author: Vogt, L.M. · Meyer, D. · Pullens, G. · Faas, M.M. · Venema, K. · Ramasamy, U. · Schols, H.A. · Vos, P. de
Keywords: Biology · Bocking antibody · Inulinase · Phorbol 13 acetate 12 myristate · Receptor activator of nuclear factor kappa B · Short chain fatty acid · Toll like receptor 2 · B lymphocyte · Cell function · Cell interaction · Cell protection · Colon carcinoma · Dietary fiber · Electric cell substrate impedance sensing · Electric resistance · Enzyme activation · Enzyme substrate · Human · Human cell · Impedance · Intestine epithelium cell · Intestine function · Permeability barrier · Regulatory mechanism · Tight junction · Transepithelial electrical resistance · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

18 Activation of the innate immune system in atherosclerotic disease
article 2007    
Author: Oude Nijhuis, M.M. · Keulen, J.K. van · Pasterkamp, G. · Quax, P.H. · Kleijn, D.P.V. de
Keywords: Biomedical Research · Atherogenesis · Infection · Inflammation · Innate immunity · Toll-like receptors · antibiotic agent · azithromycin · e 5331 · e 5531 · e 5564 · eritoran · ligand · lipid A derivative · lipopolysaccharide antagonist · low density lipoprotein · malonaldehyde · oxidized low density lipoprotein · placebo · receptor blocking agent · toll like receptor · vaccine · antigen recognition · atherogenesis · atherosclerosis · clinical trial · disease course · drug megadose · drug targeting · genetic polymorphism · human · innate immunity · knockout mouse · low drug dose · nonhuman · priority journal · review · signal transduction · vaccination · Animals · Atherosclerosis · Communicable Diseases · Humans · Immunity, Natural · Immunotherapy · Inflammation · Ligands · Lipopolysaccharides · Lipoproteins · Peptidoglycan · Signal Transduction · Toll-Like Receptors · Vaccines
[Abstract]

19 Toll-Like Receptor 4 Is Involved in Outward Arterial Remodeling
article 2004    
Author: Hollestelle, S.C.G. · Vries, M.R. de · Keulen, J.K. van · Schoneveld, A.H. · Vink, A. · Strijder, C.F. · Middelaar, B.J. van · Pasterkamp, G. · Q́uax, P.H.A. · Kleijn, D.P.V. de
Keywords: Arteries · Plaque · Proteins · Remodeling · apolipoprotein E3 · fibronectin · heat shock protein 60 · ligand · lipopolysaccharide · messenger RNA · angiogenesis · animal experiment · animal model · animal tissue · artery diameter · atherosclerotic plaque · blood vessel remodeling · carotid artery ligation · controlled study · femoral artery · immunohistochemistry · intima · male · mouse · nonhuman · priority journal · reverse transcription polymerase chain reaction · tissue structure · transgenic mouse · Western blotting · Animals · Apolipoprotein E3 · Apolipoproteins E · Arteries · Arteriosclerosis · Carotid Arteries · Female · Femoral Artery · Ligands · Membrane Glycoproteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Cell Surface · Toll-Like Receptor 4 · Toll-Like Receptors
[Abstract]

20 Stress proteins in CNS inflammation
article 2008    
Author: Noort, J.M. van
Keywords: Biology · Biomedical Research · Brain · Heat shock proteins · Inflammation · Neurodegeneration · caspase 3 · chaperone · crystallin · heat shock protein · heat shock protein 70 · heat shock protein 90 · I kappa B · immunoglobulin enhancer binding protein · protein bcl 2 · RANTES · tau protein · toll like receptor · Alexander disease · Alzheimer disease · antigen presentation · antigen presenting cell · apoptosis · central nervous system disease · cytokine production · cytotoxic T lymphocyte · degenerative disease · human · inflammation · nonhuman · Parkinson disease · priority journal · protein aggregation · protein degradation · protein expression · protein folding · protein phosphorylation · protein structure · review · Antigen Presentation · Apoptosis · Encephalomyelitis · Heat-Shock Proteins · Humans · Inflammation Mediators · Molecular Chaperones · Neurodegenerative Diseases
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date