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1 Comparative analysis of transcriptome and fitness profiles reveals general and condition-specific cellular functions involved in adaptation to environmental change in Saccharomyces cerevisiae
article 2010    
Author: Zakrzewska, A. · Boorsma, A. · Beek, A.T. · Hageman, J.A. · Westerhuis, J.A. · Hellingwerf, K.J. · Brul, S. · Klis, F.M. · Smits, G.J.
Keywords: Health · Biomedical Research · actin · transcriptome · adaptation · article · biogenesis · cell function · cell polarity · cytoskeleton · environmental stress · fungal genome · gene cluster · gene deletion · genetic transcription · nonhuman · nutrient availability · oxidative stress · phenotype · priority journal · ribosome · Saccharomyces cerevisiae · yeast cell
[Abstract]

2 Time series analysis of benzo[a]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets
article 2010    
Author: Delft, J.H.M. van · Mathijs, K. · Staal, Y.C.M. · Herwijnen, M.H.M. van · Brauers, K.J.J. · Boorsma, A. · Kleinjans, J.C.S.
Keywords: Nutrition · Biomedical Research · Carcinogen · Network · Time series · Transcription factor · Transcriptome · benzo[a]pyrene · immunoglobulin enhancer binding protein · Myc protein · serum response factor · transcription factor · transcription factor AP 1 · transcription factor E2F1 · transcriptome · amino acid metabolism · apoptosis · article · carcinogenesis · cell cycle G1 phase · cell cycle S phase · controlled study · correlation analysis · DNA adduct · DNA repair · down regulation · functional genomics · gene expression · gene regulatory network · hepatoma cell · human · human cell · lipid metabolism · named inventories, questionnaires and rating scales · proto oncogene · Short Time series Expression Miner · signal transduction · time series analysis · transcription regulation · tumor suppressor gene · upregulation
[Abstract]

3 Quenching of microbial samples for increased reliability of microarray data
article 2006    
Author: Pieterse, B. · Jellema, R.H. · Werf, M.J. van der
Keywords: Biology · Biotechnology · Microarray data · Microbial samples · Quenching · messenger RNA · transcriptome · article · cytolysis · gene · hybridization · image analysis · Lactobacillus plantarum · microarray analysis · nonhuman · operon · priority journal · RNA isolation · steady state · technique · Lactobacillus · Methanol · Protein Array Analysis · Reproducibility of Results · RNA, Bacterial · RNA, Messenger · Transcription, Genetic · Lactobacillus plantarum
[Abstract]

4 Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals
article 2005    
Author: Stierum, R. · Heijne, W. · Kienhuis, A. · Ommen, B. van · Groten, J.
Keywords: Toxicology Nutrition · Physiological Sciences · In vitro · In vivo · Liver · Toxicogenomics · bromobenzene · butylcresol · chemical compound · curcumin · food additive · gallic acid propyl ester · proteome · tiabendazole · transcriptome · biochemistry · bioinformatics · comparative toxicology · conference paper · disease marker · DNA fingerprinting · gene expression profiling · genetic procedures · genetic toxicology · genomics · in vitro study · in vivo study · laboratory · liver toxicity · metabolomics · molecular biology · nonhuman · prediction · proteomics · rat · technology · toxicological parameters · transcriptomics · Animals · Food Additives · Genomics · Humans · Liver · Toxicology
[Abstract]

5 Genomic analysis suggests higher susceptibility of children to air pollution
article 2008    
Author: Leeuwen, D.M. van · Pedersen, M. · Hendriksen, P.J.M. · Boorsma, A. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Kirsch-Volders, M. · Knudsen, L.E. · Šrám, R.J. · Bajak, E. · Delft, J.H.M. van · Kleinjans, J.C.S.
Keywords: Health · Physiological Sciences · transcriptome · adult · air pollution · article · blood analysis · cancer risk · cancer susceptibility · child · child health · controlled study · Czech Republic · data analysis · environmental exposure · environmental health · female · gene expression · gene expression profiling · genomics · human · immune response · male · micronucleus · nucleosome · parent · priority journal · Adult · Air Pollution · Child · Czech Republic · Female · Gene Expression Profiling · Gene Expression Regulation · Genetic Predisposition to Disease · Humans · Male · Nuclear Family · Parents · Receptors, Chemokine · RNA · RNA Splicing
[Abstract]

6 Generation of a catR deficient mutant of P. putida KT2440 that produces cis, cis-muconate from benzoate at high rate and yield
article 2011    
Author: Duuren, J.B.J.H. van · Wijte, D. · Leprince, A. · Karge, B. · Puchalka, J. · Wery, J. · Dos Santos, V.A.P.M. · Eggink, G. · Mars, A.E.
Keywords: Biology · 3-Fluorobenzoate · Benzoate · Catechol 1,2-dioxygenase · Cis, cis-muconate · NTG mutagenesis · P. putida KT2440 · 3-Fluorobenzoate · Benzoate · Catechol 1 ,2-dioxygenase · Cis, cis-muconate · NTG mutagenesis · P. putida KT2440 · Glucose · Mutagenesis · Phenols · Benzoic acid · Transcriptome · Article · DNA binding · Nonhuman · Operon · Priority journal · Pseudomonas putida · Transcription regulation · Pseudomonas putida · Benzoic acid, 532-32-1, 582-25-2, 65-85-0, 766-76-7 · Carbon, 7440-44-0 · Catechol 1,2 dioxygenase, 9027-16-1 · Muconic acid, 505-70-4 · Life · CBRN - CBRN Protection · EELS - Earth, Environmental and Life Sciences
[Abstract]

7 Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis
article 2008    
Author: Dihal, A.A. · Woude, H. van der · Hendriksen, P.J.M. · Charif, H. · Dekker, L.J. · IJsselstijn, L. · Boer, V.C.J. de · Alink, G.M. · Burgers, P.C. · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Biomarker · Colorectal cancer · Quercetin · Transcriptomics · fatty acid · glutathione peroxidase 2 · heat shock protein · mitogen activated protein kinase · peroxisome proliferator activated receptor alpha · quercetin · transcriptome · animal experiment · animal model · article · cancer prevention · cell cycle · colon mucosa · colorectal cancer · controlled study · down regulation · energy metabolism · Fischer 344 rat · gene expression · gene targeting · genetic analysis · glycolysis · lipid degradation · male · nonhuman · nucleotide sequence · priority journal · proteomics · rat · statistical significance · tumor biopsy · Animals · Colon · Colorectal Neoplasms · Diet · Down-Regulation · Fatty Acids · Gene Expression Profiling · Glycolysis · Intestinal Mucosa · Male · Mitochondria · Proteome · Quercetin · Rats · Rats, Inbred F344 · Rattus
[Abstract]

8 Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice
article 2012    
Author: Wopereis, S. · Radonjic, M. · Rubingh, C. · Erk, M. van · Smilde, A. · Duyvenvoorde, W. van · Cnubben, N. · Kooistra, T. · Ommen, B. van · Kleemann, R.
Keywords: Biology · Diabetes mellitus Type 2 · Diabetes mellitus Type 2-prone transgenic ApoE3Leiden mice · Plasma lipidomics · White blood cell transcriptomics · acyl coA synthetase short chain family member 2 · adp ribosylation factor gtaase activating protein 1 · atp binding cassette subfamily b protein · biological marker · cytochrome c oxidase subunit vib polypeptide 2 · cytochrome P450 2B1 · fatty acid · fibroblast growth factor 16 · lipidome · seryl aminoacyl tRNA synthetase 2 · transcription elongation factor a like 8 protein · transcriptome · transferrin receptor · unclassified drug · animal cell · animal experiment · animal model · area under the curve · article · blood analysis · controlled study · disease course · gene expression · glucose intolerance · glucose tolerance test · leukocyte · lipid blood level · lipid diet · lipidomics · mouse · nonhuman · prediction · priority journal · prognosis · protein analysis · transcriptomics · Healthy for Life · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences
[Abstract]

9 Metabolic flux analysis of a phenol producing mutant of Pseudomonas putida S12: Verification and complementation of hypotheses derived from transcriptomics
article 2009    
Author: Wierckx, N. · Ruijssenaars, H.J. · Winde, J.H.de · Schmid, A. · Blank, L.M.
Keywords: Biology · Biomedical Research · Metabolic engineering · Metabolic flux analysis · Phenol · Pseudomonas putida S12 · Solvent tolerance · Carbon fluxes · Carbon metabolism · Cellular events · Complementation · Encoding genes · Energy productions · Glucose 6 phosphates · In-vitro · Metabolic engineering · Metabolic flux · Metabolic flux analysis · Pentose phosphate pathway · Phenol production · Phosphate production · Phosphoenolpyruvates · Physiological effects · Pseudomonas putida · Pseudomonas putida S12 · Pyruvate kinase · Pyruvates · Solvent tolerance · Substrate uptake · TCA cycle · Transcriptional changes · Transcriptome analysis · Transcriptomics · Up-regulation · Encoding (symbols) · Gene encoding · Glucose · Phenols · Solvents · Substrates · Metabolism · bacterial protein · glucose 6 phosphate · gntP protein · gnuK protein · lactate dehydrogenase · malate dehydrogenase · malic acid · oprB 1 protein · oxaloacetic acid · phenol · phosphoenolpyruvate · porin · pykA protein · pyruvate kinase · pyruvic acid · unclassified drug · article · bacterial metabolism · bacterial strain · carbon metabolism · carbon source · complex formation · controlled study · energy metabolism · gene mutation · gluconeogenesis · metabolic engineering · nonhuman · priority journal · Pseudomonas putida · transcription regulation · transcriptomics · upregulation · Pseudomonas putida
[Abstract]

10 Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole
article 2008    
Author: Stierum, R. · Conesa, A. · Heijne, W. · Ommen, B.v. · Junker, K. · Scott, M.P. · Price, R.J. · Meredith, C. · Lake, B.G. · Groten, J.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Butylated hydroxytoluene · Curcumin · Drug metabolism · Mixtures · p53 · Peroxisome proliferation · Propyl gallate · Rat · Thiabendazole · Toxicogenomics · butylcresol · complementary DNA · curcumin · cyanide · cytochrome P450 · cytochrome P450 2B1 · cytochrome P450 2B2 · cytochrome P450 2C6 · cytochrome p450 3a9 · cytochrome p450 4a3 · enoyl coenzyme A hydratase · enzyme · gallic acid propyl ester · glutathione transferase · growth arrest and DNA damage inducible protein 45 · palmitoyl coenzyme A · phytanoyl coenzyme a dioxygenase · protein kinase C beta · protein p53 · RNA · serum albumin · tiabendazole · transcriptome · animal tissue · article · controlled study · diet · DNA microarray · food poisoning · gene expression · gene expression profiling · liver · male · metabolism · nonhuman · nucleotide sequence · rat · real time polymerase chain reaction · Western blotting · Animals · Aryl Hydrocarbon Hydroxylases · Body Weight · Butylated Hydroxytoluene · Curcumin · Cytochrome P-450 CYP1A2 · Cytochrome P-450 CYP2B1 · Data Interpretation, Statistical · Diet · DNA, Complementary · Food Additives · Gene Expression · Gene Expression Profiling · Glutathione Transferase · Liver · Male · Organ Size · Oxidation-Reduction · Palmitoyl Coenzyme A · Propyl Gallate · Rats · Rats, Sprague-Dawley · Reverse Transcriptase Polymerase Chain Reaction · Steroid Hydroxylases · Thiabendazole · Rattus
[Abstract]

Search results also available in MS Excel format.

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