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1 Generation of fibrinolytic activity in bovine plasma by the combined effects of chloroform and dextran sulphate
article 1981    
Author: Jenks, R.L. · Kluft, C. · Astrup, T.
Keywords: Fibrinolysis · Chloroform · Dextran sulphate · Urokinase inhibitor
[Abstract]

2 Comparison of the inhibition of urokinase-type plasminogen activator (u-PA) activity by monoclonal antibodies specific for u-PA as assessed by different assays
article 1995    
Author: Boheemen, P.A. van · Hoogen, N.M. van den · Koolwijk, N.
Keywords: Biology · monoclonal antibody · urokinase · article · controlled study · enzyme inhibition · fibrinolysis · priority journal
[Abstract]

3 The inactivation of single-chain urokinase-type plasminogen activator by thrombin in a plasma milieu : effect of thrombomodulin
article 1998    
Author: Braat, E.A.M. · Los, P. · Rijken, D.C.
Keywords: Fibrinolysis · Inhibition · Protein C · Thrombin · Thrombomodulin · Urokinase · Fibrinolysis · Humans · Kinetics · Plasma · Thrombin · Thrombomodulin · Urinary Plasminogen Activator
[Abstract]

4 Inhibition of urokinase-type and tissue-type plasminogen activator - Mediated plasminogen activation by doxycycline
article 1996    
Author: Hanemaaijer, R. · Visser, H. · Hoogen, C.M. van den · Sorsa, T. · Hinsbergh, V.W.M. van
Keywords: Biology · doxycycline · tissue plasminogen activator · urokinase · conference paper · fibrinolysis · human · plasminogen activation · priority journal
[Abstract]

5 In vivo and in vitro interaction of high and low molecular weight single-chain urokinase-type plasminogen activator with rat liver cells
article 1992    
Author: Kuiper, J. · Rijken, D.C. · Munk, G.A. · Berkel, T.J. van
Keywords: Biology · Biological Transport · Cells, Cultured · Embryo, Mammalian · Humans · Iodine Radioisotopes · Isoenzymes/blood · Isoenzymes/metabolism · Isoenzymes/pharmacokinetics · Kidney/enzymology · Kinetics · Liver/metabolism · Male · Metabolic Clearance Rate · Molecular Weight · Radioisotope Dilution Technique · Rats · Rats, Inbred Strains · Tissue Distribution · Urokinase-Type Plasminogen Activator/blood · Urokinase-Type Plasminogen Activator/metabolism · Urokinase-Type Plasminogen Activator/pharmacokinetics · Iodine Radioisotopes · Isoenzymes · Urokinase-Type Plasminogen Activator
[PDF] [Abstract]

6 The suitability of various plasmin preparations for the functional assay of ??2-antiplasmin in plasma
article 1982    
Author: Kluft, C. · Traas, D.W. · Jie, A.F.H. · Hoegee de Nobel, E.
Keywords: Biology · Alpha 2 antiplasmin · Urokinase · Blood and hemopoietic system · Fibrinolysis · Human · Methodology · Antiplasmin · Blood Coagulation Tests · Human · Lysine · Plasmin
[Abstract]

7 Urokinase and tissue-type plasminogen activator stimulate human vascular smooth muscle cell migration
article 1996    
Author: Wijnberg, M.J. · Nieuwenbroek, N.M.E. · Slomp, J. · Quax, P.H.A. · Verheijen, J.H.
Keywords: Biology · Alteplase · Plasminogen activator · Tissue plasminogen activator · Urokinase · Cell migration · Conference paper · Controlled study · Human · Human cell · Smooth muscle fiber · Vascular smooth muscle
[Abstract]

8 Plasma clearance of urokinase-type plasminogen activator
article 1998    
Author: Kaaden, M.E. van der · Rijken, D.C. · Berkel, T.J.C. van · Kuiper, J.
Keywords: Health · urokinase receptor · blood clot lysis · drug receptor binding · endothelium cell · extracellular matrix · glycosylation · internalization · liver metabolism · nonhuman · plasma clearance · plasminogen activation · priority journal · protein isolation · review

9 Difference in expression of the plasminogen activation system in synovial tissue of patients with rheumatoid arthritis and osteoarthritis
article 1996    
Author: Ronday, H.K. · Smits, H.H. · Muijen, G.N.P. van · Pruszczynski, M.S.M. · Dolhain, R.J.E.M. · Langelaan, E.J. van · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology · Immunohistochemistry · Osteoarthritis · Plasminogen activation · Rheumatoid arthritis · Urokinase · fibrin · plasminogen activator · plasminogen activator inhibitor · urokinase · article · clinical article · gene expression · human tissue · immunohistochemistry · nonhuman · osteoarthritis · priority journal · rheumatoid arthritis · synovium · Arthritis, Rheumatoid · Enzyme Activation · Humans · Immunohistochemistry · Osteoarthritis · Plasminogen · Plasminogen Activator Inhibitor 1 · Plasminogen Activator Inhibitor 2 · Plasminogen Activators · Receptors, Cell Surface · Synovial Membrane · Tissue Plasminogen Activator · Urinary Plasminogen Activator
[Abstract]

10 Activation of plasminogen by tissue activator is increased specifically in the presence of certain soluble fibrin(ogen) fragments
article 1982    
Author: Verheijen, J.H. · Nieuwenhuizen, W. · Wijngaards, G.
Keywords: Biology · fibrin(ogen) fragments · plasminogen activation · Tissue plasminogen activator · urokinase · fibrin · fibrin degradation product · fibrinmonomer · fibrinogen · fibrinogen D fragment · fibrinogen fragment e · fibrinogen fragment x · fibrinogen fragment y · plasminogen · plasminogen activator · thromboplastin · urokinase · article · human · metabolism · Fibrin · Fibrin Fibrinogen Degradation Products · Fibrinogen · Human · Plasminogen · Plasminogen Activators · Support, Non-U.S. Gov't · Thromboplastin · Urinary Plasminogen Activator
[Abstract]

11 Binding of human urokinase-type plasminogen activator to its receptor : Residues involved in species specificity and binding
article 1998    
Author: Quax, P.H.A. · Grimbergen, J.M. · Lansink, M. · Bakker, A.H.F. · Blatter, M.C. · Belin, D. · Hinsbergh, V.W.M. van · Verheijen, J.H.
Keywords: Health · Site-directed mutagenesis · Urokinase-type plasminogen activator · Urokinase-type plasminogen activator receptor · Amino Acid Sequence · Animals · Asparagine · Binding, Competitive · Cells, Cultured · Cricetinae · Endothelium, Vascular · Humans · Ligands · Mice · Molecular Sequence Data · Mutagenesis, Site-Directed · Receptors, Cell Surface · Sequence Homology, Amino Acid · Species Specificity · Swine · Tyrosine · Urinary Plasminogen Activator
[Abstract]

12 A sensitive bioimmunoassay for thrombin-cleaved two-chain urokinase-type plasminogen activator in human body fluids
article 1996    
Author: Braat, E.A.M. · Nauland, U. · Dooijewaard, G. · Rijken, D.C.
Keywords: Biology · Cathepsin · Urokinase · Bioassay · Blood level · Clinical trial · Controlled clinical trial · Controlled study · Immunoassay · Protein degradation · Rheumatoid arthritis · Sepsis · Synovial fluid level · Body Fluids · Humans · Immunoenzyme Techniques · Sensitivity and Specificity · Thrombin · Urinary Plasminogen Activator
[Abstract]

13 A novel and simple immunocapture assay for determination of gelatinase-B (MMP-9) activities in biological fluids : Saliva from patients with Sjögren's syndrome contain increased latent and active gelatinase-B levels
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Konttinen, Y.T. · Koolwijk, P. · Verheijen, J.H.
Keywords: Health · Activity assay · Gelatinase B · Matrix metalloproteinases (MMP) · Sjogren's syndrome · Urokinase · Animals · Antibodies, Monoclonal · Antibody Specificity · Collagenases · Female · Humans · Immunoassay · Matrix Metalloproteinase 9 · Mice · Mice, Inbred BALB C · Saliva · Sensitivity and Specificity · Sjogren's Syndrome · Tissue Inhibitor of Metalloproteinase-2 · Animalia
[Abstract]

14 Markers of fibrinolytic potency and clotting activation in stable angina pectoris : Role of urokinase, assessment of atrioventricular differences and correlation with coronary patency
article 1999    
Author: Páramo, U.A. · Panizo, C. · Montes, R. · Orbe, J. · Alegría, E. · Martínez-Caro, D. · Dooijewaard, G.
Keywords: Biology · biochemical marker · urokinase · adult · aged · angina pectoris · blood clotting · blood sampling · coronary blood vessel · drug effect · drug potency · enzyme activity · female · fibrinolysis · graft patency · hemostasis · human · major clinical study · male · protein degradation · thrombogenesis
[Abstract]

15 Synthesis, storage and regulated secretion of tissue-type plasminogen activator by cultured rat heart endothelial cells
article 1998    
Author: Emeis, J.J. · Hoogen, C.M. van den · Diglio, C.A.
Keywords: Health · 8 bromo cyclic amp · calcimycin · cholera toxin · forskolin · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor · retinoic acid · thrombin · tissue plasminogen activator · urokinase · animal cell · article · controlled study · heart · nonhuman · priority journal · protein secretion · protein synthesis · rat · vascular endothelium
[Abstract]

16 Alpha- and beta-adrenergic influences on the tissue and urokinase plasminogen activator systems
article 1999    
Author: Larsson, P.T. · Wallén, N.H. · Wiman, B. · Dooijewaard, G.
Keywords: adrenalin · isoprenaline · noradrenalin · phentolamine · phentolamine mesylate · plasminogen activator inhibitor 1 · propranolol · tissue plasminogen activator · urokinase · controlled study · dose response · drug potentiation · fibrinolysis · heart rate · human · human experiment · intravenous drug administration · male
[Abstract]

17 Active TGF-β1 correlates with myofibroblasts and malignancy in the colorectal adenoma-carcinoma sequence
article 2009    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Reijden, J.J. van der · Zon, J.M. van der · Verheijen, J.H. · Hommes, D.W. · Lamers, C.B.H.W. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · actin · desmin · keratin · plasminogen activator inhibitor 1 · Smad2 protein · SMAD2 protein, human · transforming growth factor beta1 · tumor marker · urokinase · vimentin · adenoma · article · carcinoma · cell strain HT29 · colorectal tumor · enzyme linked immunosorbent assay · female · fibroblast · human · immunohistochemistry · male · metabolism · pathology · reproducibility · sensitivity and specificity · smooth muscle · Actins · Adenoma · Carcinoma · Colorectal Neoplasms · Desmin · Enzyme-Linked Immunosorbent Assay · Female · Fibroblasts · HT29 Cells · Humans · Immunohistochemistry · Keratins · Male · Muscle, Smooth · Plasminogen Activator Inhibitor 1 · Reproducibility of Results · Sensitivity and Specificity · Smad2 Protein · Transforming Growth Factor beta1 · Tumor Markers, Biological · Urokinase-Type Plasminogen Activator · Vimentin
[Abstract]

18 A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease
article 2010    
Author: Eefting, D. · Seghers, L. · Grimbergen, J.M. · Vries, M.R. de · Boer, H.C. de · Lardenoye, J.W.H.P. · Jukema, J.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Health · Biomedical Research · Gene therapy · Matrix metalloproteinases · Plasmin(ogen) · Vascular surgery · Vein graft disease · apolipoprotein E3 · aprotinin · hybrid protein · matrix metalloproteinase · matrix metalloproteinase inhibitor · plasmin · plasmin inhibitor · plasminogen activator · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 1 amino terminal fragment of urokinase type plasminogen activator bovine pancreas trypsin inhibitor · unclassified drug · urokinase receptor · animal cell · animal experiment · animal model · animal tissue · article · carotid artery · cell surface · controlled study · electroporation · expression vector · female · gene overexpression · gene targeting · genetic transfection · human · human tissue · hypercholesterolemia · in vivo culture · intima · male · mouse · nonhuman · nonviral gene delivery system · priority journal · vein graft disease
[Abstract]

19 Pericellular-acting proteases in human first trimester decidua
article 2008    
Author: Plaisier, M. · Koolwijk, P. · Willems, F. · Helmerhorst, F.M. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Decidua · First trimester · Matrix metalloproteinases · Trophoblast · UNK cells · CD56 antigen · CD68 antigen · matrix metalloproteinase · messenger RNA · proteinase · urokinase · urokinase receptor · adult · article · cell count · controlled study · decidua · female · first trimester pregnancy · gene expression · human · human cell · human tissue · immunohistochemistry · macrophage · natural killer cell · pathophysiology · pregnancy termination · priority journal · protein analysis · protein degradation · protein expression · protein function · quantitative analysis · reverse transcription polymerase chain reaction · spontaneous abortion · trophoblast · Adult · Antigens, CD · Antigens, CD56 · Antigens, Differentiation, Myelomonocytic · Decidua · Female · Humans · Immunohistochemistry · Matrix Metalloproteinase 14 · Matrix Metalloproteinase 20 · Peptide Hydrolases · Pregnancy · Pregnancy Trimester, First · Reverse Transcriptase Polymerase Chain Reaction · Healthy for Life · Healthy Living
[Abstract]

20 Aminopeptidase inhibitor bestatin stimulates microvascular endothelial cell invasion in a fibrin matrix
article 2003    
Author: Hensbergen, Y. van · Broxterman, H.J. · Peters, E. · Rana, S. · Elderkamp, Y.W. · Hinsbergh, V.W.M. van · Koolwijk, P.
Keywords: Biomedical Research · Angiogenesis · Bestatin · u-PAR · actinonin · amastatin · antibody · antineoplastic agent · basic fibroblast growth factor · enzyme inhibitor · microsomal aminopeptidase · MY 7 antibody · unclassified drug · urokinase · urokinase receptor · vasculotropin · WM15 antibody · angiogenesis · cell invasion · concentration (parameters) · controlled study · dose response · drug effect · endothelium cell · enzyme activity · human cell · hypothesis · priority journal · protein expression · stroma · tumor · vascular endothelium · Aminopeptidases · Antigens, CD13 · Cell Movement · Cells, Cultured · Dose-Response Relationship, Drug · Endothelium, Vascular · Fibrin · Humans · Integrins · Leucine · Microcirculation · Neovascularization, Physiologic · Receptors, Cell Surface · Umbilical Veins · Urinary Plasminogen Activator
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by date