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1 A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices
article 2014    
Author: Westerhout, J. · Steeg, E. van de · Grossouw, D. · Zeijdner, E.E. · Krul, C.A.M. · Verwei, M. · Wortelboer, H.M.
Keywords: Biology · Caco-2 · Food-effect · Human intestine · Intestinal absorption · InTESTine™ · Porcine intestine · Acebutolol · Atenolol · Candesartan · Cetirizine · Cimetidine · Ciprofloxacin · Diazepam · Digoxin · Famotidine · Hydrocortisone · Ibuprofen · Indometacin · Mannitol · Melagatran · Metoprolol · Mucin · Oxprenolol · Phenazone · Pindolol · Propranolol · Ranitidine · Salazosulfapyridine · Salicylic acid · Testosterone · Verapamil · Active transport · Animal tissue · CACO 2 cell line · Controlled study · Domestic pig · Drug absorption · Drug bioavailability · Drug penetration · Drug transport · Electric resistance · Ex vivo study · Female · Human · Human tissue · Intestine absorption · Intestine mucosa · Male · Nonhuman · Passive transport · Prediction · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

2 Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3
article 2014    
Author: Gozalpour, E. · Greupink, R. · Wortelboer, H.M. · Bilos, A. · Schreurs, M. · Russel, F.G.M. · Koenderink, J.B.
Keywords: Biology Pharmacology · Bufadienolides · Cardenolides · Cell transport · Convallatoxin · Digitalis-like compounds · Dihydroouabain · Drug-induced toxicity · NTCP · OATP1B1 · OATP1B3 · Ouabagenin · Ouabain · Cardiac glycoside · Convallatoxin · Cymarin · Dehydroouabain · Digitoxigenin · Digitoxin · Digoxigenin · Digoxin · Dihydroouabain · Estradiol 17 glucuronide · Gitoxigenin · Hydroxyl group · Ouabagenin · Ouabain · Peruvoside · Plant glycoside · Proscillaridin · Sodium bile acid cotransporter · Solute carrier organic anion transporter 1B1 · Solute carrier organic anion transporter 1B3 · Strophanthidin · Strophanthidol · Sugar · Taurocholic acid · Unclassified drug · Animal cell · Chemical structure · CHO cell line · Controlled study · Drug interaction · Drug uptake · Embryo · Human · Human cell · IC 50 · Kidney cell · Liquid chromatography · Mass spectrometry · Nonhuman · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

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