Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 285 found. Next | Sort by relevance

1 Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study
article 2018    
Author: Morrison, M.C. · Kleemann, R. · Koppen, A. van · Hanemaaijer, R. · Verschuren, L.
Keywords: Biology · Liver · NASH, · Inflammation · Molecular · Gene expression · Translational · Mouse · Human · Translational · Cytokine · Growth factor · Transcription factor · Animal experiment · Animal model · Controlled study · Extracellular matrix · Gene expression profiling · Human tissue · Inflammation · Lipid diet · Lipid metabolism · Liver biopsy · Mouse · Nonalcoholic fatty liver · Nonhuman · Transcriptomics · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

2 Determinants of postprandial plasma bile acid kinetics in human volunteers
article 2017    
Author: Fiamoncini, J. · Yiorkas, A.M. · Gedrich, K. · Rundle, M. · Alsters, S.I. · Roeselers, G. · Broek, T.J. van den · Clavel, T. · Lagkouvardos, I. · Wopereis, S. · Frost, G. · Ommen, B. van · Blakemore, A.I. · Daniel, H.
Keywords: Biology · Bile acids · Mixed-meal tolerance test · Oral glucose tolerance test · Postprandial · SLCO1A2 · Chenodeoxycholic acid · Cholic acid · Deoxycholic acid · Genomic DNA · Glycine · Glycochenodeoxycholic acid · Glycocholic acid · Glycodeoxycholic acid · Glycoursodeoxycholic acid · Solute carrier organic anion transporter 1A2 · Taurine · Taurochenodeoxycholic acid · Taurocholic acid · Taurodeoxycholic acid · Taurolitocholic acid · Tauroursodeoxycholic acid · Unclassified drug · Ursodeoxycholic acid · Bile acid blood level · Bile acid synthesis · Clinical trial · Diet restriction · Dietary intake · Enterohepatic circulation · Feces microflora · Gene expression · Genome analysis · Kinetics · Liquid chromatography-mass spectrometry · Oral glucose tolerance test · Phenotype · Postprandial state · Quantitative analysis · Sex difference · Weight reduction · Whole exome sequencing · Blood · Controlled study · Physiology · Randomized controlled trial · Bile Acids and Salts · Fasting · Female · Humans · Male · Metabolic Clearance Rate · Middle Aged · Postprandial Period · Weight Loss · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis
article 2017    
Author: Hoeke, G. · Wang, Y. · Dam, A.D. van · Mol, M. · Gart, E. · Klop, H.G. · Berg, S.M. van den · Pieterman, E.H. · Princen, H.M.G. · Groen, A.K. · Rensen, P.C.N. · Berbée, J.F.P. · Boon, M.R.
Keywords: Biology · Atherosclerosis · Brown adipose tissue · Hypercholesterolemia · Cholesterol metabolism · Lipid and lipoprotein metabolism · 5 [2 [[2 (3 chlorophenyl) 2 hydroxyethyl]amino]propyl] 1,3 benzodioxole 2,2 dicarboxylic acid · Atorvastatin · Cholesterol · Fatty acid · High density lipoprotein cholesterol · Lipoprotein · Proprotein convertase 9 · Triacylglycerol · Animal experiment · Animal model · Animal tissue · Atherosclerosis · Brown adipose tissue · Cholesterol blood level · Controlled study · Drug effect · Drug potentiation · Energy expenditure · Female · Gene expression · Hypercholesterolemia · Lipid composition · Lipid liver level · Lipid metabolism · Lipid oxidation · Lipid transport · Lipoprotein metabolism · Mouse · Nonhuman · Triacylglycerol blood level · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

4 Lactobacillus plantarum NCIMB8826 ameliorates inflammation of colon and skin in human APOC1 transgenic mice
article 2016    
Author: Mariman, R. · Reefman, E. · Tielen, F. · Persoon-Deen, C. · Mark, K. van de · Worms, N. · Koning, F. · Nagelkerken, L.
Keywords: Biology · APOC1+/+ transgenic mice model · Gene expression profiling · Intestine · Mast cells · Probiotics · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

5 A user-friendly workflow for analysis of Illumina gene expression bead array data available at the arrayanalysis.org portal
article 2015    
Author: Goelela, V.S. · Kelder, T. · Adriaens, M.E. · Evelo, C.T. · Radonijc, M.
Keywords: Biology · Microarray · Illumina bead array · Transcriptomics · Data analysis; Normalization · Quality control · Data analysis · Normalization · Computer interface · Effect size · Gene expression · Human · Illumina bead array · Microarray analysis · Statistical analysis · Workflow · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

6 The probiotic mixture VSL#3 has differential effects on intestinal immune parameters in healthy female BALB/c and C57BL/6 mice
article 2015    
Author: Mariman, R. · Tielen, F. · Koning, F. · Nagelkerken, L.
Keywords: Biology · Flow cytometry · Host genetics · Immune modulation · Microarray · Probiotics · Chemokine receptor CCR5 · Chemokine receptor CXCR3 · Eosinophil peroxidase · Gamma interferon inducible protein 10 · Interleukin 12 receptor beta1 · Retinoid related orphan receptor gamma · Transcription factor GATA 3 · VSL3 · Adaptive immunity · Animal experiment · Colon · Controlled study · Female · Gene expression · Genetic variability · Homeostasis · Immunomodulation · Innate immunity · Intestine mucosa · Major histocompatibility complex · Mesentery lymph node · Microarray analysis · Mouse · Mouse strain · Nonhuman · Phenotype · Principal component analysis · Protein expression · Single drug dose · Small intestine · Upregulation · Mus · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

7 Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes
article 2015    
Author: Liang, W. · Verschuren, L. · Mulder, P. · Hoorn, J.W.A. van der · Verheij, J. · Dam, A.D. van · Boon, M.R. · Princen, H.M.G. · Havekes, L.M. · Kleemann, R. · Hoek, A.M. van den
Keywords: Biology · Alanine aminotransferase · Aspartate aminotransferase · Glucose · High density lipoprotein cholesterol · Insulin · Interleukin 6 · Low density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Salsalate · Triacylglycerol · Alanine aminotransferase blood level · Animal cell · Animal experiment · Animal model · Animal tissue · Aspartate aminotransferase blood level · Body weight · Controlled study · Down regulation · Drug efficacy · Drug response · Dyslipidemia · Energy metabolism · Fatty acid oxidation · Fatty liver · Gene expression · Glucose blood level · Glycemic control · Hepatitis · Insulin blood level · Insulin resistance · Lipid metabolism · Lipogenesis · Male · Mouse · Nonalcoholic fatty liver · Nonhuman · Treatment duration · Treatment outcome · Triacylglycerol blood level · Upregulation · Weight gain · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

8 Spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo
article 2015    
Author: Higuera, G.A. · Fernandes, H. · Spitters, T.W.G.M. · Peppel, J. van de · Aufferman, N. · Truckenmueller, R. · Escalante · Stoop, R. · Leeuwen, J.P. van · Boer, J. de · Subramaniam, V. · Karperien, M. · Blitterswijk, C. van · Boxtel, A. van · Moroni, L.
Keywords: Biology · Angiogenesis · ECM (extracellular matrix) · Mesenchymal stromal cells · Microarchitecture · Molecular gradients · Blood vessels · Cell death · Cell proliferation · Cells · Cytology · Flowcharting · Gene expression · Genes · Nutrients · Cell culture · Hypocalcin · Animal cell · Animal experiment · Bone marrow derived mesenchymal stem cell · Cell adhesion · Controlled study · Hypoxia · In vitro study · In vivo study · Mouse · Nonhuman · Nutrient availability · Nutrient limitation · Phenotype · Protein expression · Spatiotemporal analysis · Surface area · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

9 Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet
article 2015    
Author: Derous, D. · Kelder, T. · Schothorst, E.M. van · Erk, M. van · Voigt, A. · Klaus, S. · Keijer, J. · Radonjic, M.
Keywords: Adipose tissue · Data integration · High-fat diet · Network analysis · Systems biology · Transcriptional regulation · Transcriptomics · Transforming growth factor beta · Adaptation · Analytic method · Animal tissue · Caloric intake · Cell respiration · Controlled study · Disorders of mitochondrial functions · Down regulation · Epididymis fat · Gene expression · Immune response · Lipid diet · Low fat diet · Male · Metabolic regulation · Mouse · Network analysis · Nonhuman · Organ weight · Signal transduction · Stress · Transcription regulation · White adipose tissue · Murinae · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

10 Toxicogenomics directory of chemically exposed human hepatocytes
article 2014    
Author: Grinberg, M. · Stöber, R.M. · Edlund, K. · Rempel, E. · Godoy, P. · Reif, R. · Widera, A. · Madjar, K. · Schmidt-Heck, W. · Marchan, R. · Sachinidis, A. · Spitkovsky, D. · Hescheler, J. · Carmo, H. · Arbo, M.D. · Water, B. van de · Wink, S. · Vinken, M. · Rogiers, V. · Escher, S. · Hardy, B. · Mitic, D. · Myatt, G. · Waldmann, T. · Mardinoglu, A. · Damm, G. · Seehofer, D. · Nüssler, A. · Weiss, T.S. · Oberemm, A. · Lampen, A. · Schaap, M.M. · Luijten, M. · van Steeg, H. · Thasler, W.E. · Kleinjans, J.C.S. · Stierum, R.H. · Leist, M. · Rahnenführer, J. · Hengstler, J.G.
Keywords: Biology · Bioinformatics · Biomarker identification · Cirrhosis · Hepatocellular cancer · Hepatotoxicity · In vivo validation · SEURAT-1 · Steatosis · Toxicotranscriptomics · Unsupervised clustering · allyl alcohol · biological marker · chemical compound · cytochrome P450 1A1 · cytochrome P450 3A4 · galactosamine · isoniazid · ketoconazole · liver protein · paracetamol · propranolol · thyroid hormone · transcription factor · triazolam · valproic acid · binding site · cell stress · data base · down regulation · fatty liver · gene expression · gene ontology · human · liver cell · liver cell carcinoma · liver cirrhosis · liver disease · microarray analysis · mutation · nonalcoholic fatty liver · quantitative analysis · real time polymerase chain reaction · RNA extraction · toxicogenomics · transcriptomics · upregulation · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

11 Zebrafish embryotoxicity test for developmental (neuro)toxicity: Demo case of an integrated screening approach system using anti-epileptic drugs
article 2014    
Author: Beker van Woudenberg, A. · Snel, C. · Rijkmans, E. · Groot, D. de · Bouma, M. · Hermsen, S. · Piersma, A. · Menke, A. · Wolterbeek, A.
Keywords: Biology · Antiepileptic drugs · Behavior · Developmental (neuro)toxicity · Gene expression · Histopathology · Integrated test strategy · Kinetics · Zebrafish embryotoxicity test (ZET) · Anticonvulsive agent · Carbamazepine · Cytochrome P450 26A1 · Ethosuximide · Etiracetam · Valproic acid · ALDH1A2 gene · Animal cell · Animal experiment · Animal model · Animal tissue · Case study · Cell vacuole · Concentration (parameters) · Controlled study · CYP26A1 gene · Demo case study · Developmental toxicity · Edema · Embryo · Embryotoxicity · Experimental design · Female · Gene · Gene expression · Histopathology · In situ hybridization · Larva · Liver cell · Male · Morphology · Motor activity · Nerve degeneration · Neurotoxicity · Nonhuman · Nucleotide sequence · Pericardial disease · Pericardial edema · Phenotype · Predictive value · Sensitivity analysis · Swimming · Toxicity testing · Toxicokinetics · Whole mount in situ hybridization · Zebra fish · Zebrafish embryotoxicity test · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Aspergillus niger RhaR, a regulator involved in L-rhamnose release and catabolism
article 2014    
Author: Gruben, B.S. · Zhou, M. · Wiebenga, A. · Ballering, J. · Overkamp, K.M. · Punt, P.J. · Vries, R.P. de
Keywords: Biology · Aspergillus niger · L-rhamnose catabolism · L-rhamnose release · Pectin degradation · Transcriptional regulation · Aspergillus · Encoding (symbols) · Industrial applications · Metabolism · Down-regulation · Filamentous fungi · L-rhamnose · Regulatory genes · Rhamnogalacturonan-I · Small reduction · Gene encoding · Galacturonic acid · Pectin · Pectin lyase · Polygalacturonase · Rhamnose · Biodegradation · Catabolism · Enzyme activity · Genome · Growth rate · Amino acid sequence · Carbohydrate metabolism · Carbon source · DNA flanking region · Fungal gene · Fungal genome · Fungal strain · Fungus culture · Fungus growth · Gene expression · Gene identification · Gene inactivation · Microarray analysis · Mycelium · Nonhuman · Orthology · Regulator gene · RhaR gene · Transcription regulation · Fungi · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

13 Differential modulation by Akkermansia muciniphila and faecalibacterium prausnitzii of host peripheral lipid metabolism and histone acetylation in mouse gut organoids
article 2014    
Author: Lukovac, S. · Belzer, C. · Pellis, L. · Keijser, B.J. · Vos, W.M. de · Montijn, R.C. · Roeselers, G.
Keywords: Biology · G protein coupled receptor 43 · Histone deacetylase · Membrane protein · Peroxisome proliferator activated receptor gamma · Protein Fiaf · Short chain fatty acid · Unclassified drug · Adult · Animal experiment · Animal tissue · Bacterial strain · Cell cycle regulation · Cell metabolism · Controlled study · Down regulation · Epigenetics · Ex vivo study · Fiaf gene · Gene · Gene control · Gene expression · Gene silencing · Gpr43 gene · Hdac3 gene · Hdac5 gene · Histone acetylation · Host pathogen interaction · Ileum · In vivo study · Intestine flora · Lipid metabolism · Lipolysis · Male · Mouse · Nonhuman · Nucleotide sequence · Ppargamma gene · Satiety · Transcription regulation · Akkermansia muciniphila · Faecalibacterium prausnitzii · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

14 The probiotic mixture VSL#3 mediates both pro- and anti-inflammatory responses in bone marrow-derived dendritic cells from C57BL/6 and BALB/c mice
article 2014    
Author: Mariman, R. · Kremer, S.H.A. · Koning, F. · Nagelkerken, L.
Keywords: Biology · Bagg albino mouse · Biosynthesis · C57BL mouse · Dendritic cell · Drug effects · Genetics · immunology · Metabolism · Physiology · Animals · Anti-Inflammatory Agents · Bifidobacterium · Bone Marrow Cells · Chemokines · Cytokines · Dendritic Cells · Gene Expression Profiling · Gene Expression Regulation · Immunologic Factors · Inflammation · Lactobacillus · Lipopolysaccharides · Mice · Mice, Inbred BALB C · Mice, Inbred C57BL · Probiotics · RNA, Messenger · Signal Transduction · Th1 Cells · Th2 Cells · Toll-Like Receptors · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

15 Bioinformatics Methods for Interpreting Toxicogenomics Data: The Role of Text-Mining
bookPart 2014    
Author: Hettne, K.M. · Kleinjans, J. · Stierum, R.H. · Boorsma, A. · Kors, J.A.
Keywords: Biology · Bioinformatics · Gene-expression profiling · Gene-set analysis · Text-mining · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

16 Functions of the CCCH type zinc finger protein OsGZF1 in regulation of the seed storage protein GluB-1 from rice
article 2014    
Author: Chen, Y. · Sun, A. · Wang, M. · Zhu, Z. · Ouwerkerk, P.B.F.
Keywords: Biology · CCCH · GluB-1 · Glutelin · Repressor · Rice · Zinc finger · DNA binding protein · GluB 1 protein, Oryza · GluB-1 protein, Oryza · Gluten · Nitrogen · Vegetable protein · Zinc finger protein · Binding site · Cytology · DNA sequence · Down regulation · Gene expression regulation · Gene library · Genetics · Metabolism · Molecular genetics · Nucleotide sequence · Physiology · Plant seed · Promoter region · Reporter gene · Rice · RNA interference · Transgenic plant · Two hybrid system · Base Sequence · Binding Sites · DNA-Binding Proteins · Down-Regulation · Gene Expression Regulation, Plant · Gene Library · Genes, Reporter · Glutens · Molecular Sequence Data · Nitrogen · Oryza sativa · Plant Proteins · Plants, Genetically Modified · Promoter Regions, Genetic · RNA Interference · Seeds · Sequence Analysis, DNA · Two-Hybrid System Techniques · Zinc Fingers · Healthy for Life · Healthy Living Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

17 Novel combination of collagen dynamics analysis and transcriptional profiling reveals fibrosis-relevant genes and pathways
article 2013    
Author: Blaauboer, M.E. · Emson, C.L. · Verschuren, L. · Erk, M. van · Turner, S.M. · Everts, V. · Hanemaaijer, R. · Stoop, R.
Keywords: Biology · Bleomycin · Cell proliferation · Extracellular matrix · Gene expression · Lung fibrosis · New collagen formation · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

18 Monounsaturated and Saturated, but Not n-6 Polyunsaturated Fatty Acids Decrease Cartilage Destruction under Inflammatory Conditions: A Preliminary Study
article 2013    
Author: Bastiaansen-Jenniskens, Y.M. · Siawash, M. · Lest, C.H.A. van de · Verhaar, J.A.N. · Kloppenburg, M. · Zuurmond, A.M. · Stojanovic-Susulic, V. · Osch, G.J.V.M. van · Clockaerts, S.
Keywords: Health · Cartilage · Chondrocyte · Fatty acids · Collagenase 3 · Disintegrin · Glyceraldehyde 3 phosphate dehydrogenase · Glycosaminoglycan · Interstitial collagenase · Lactate dehydrogenase · Linoleic acid · Monounsaturated fatty acid · Oleic acid · Palmitic acid · Polyunsaturated fatty acid · Prostaglandin E2 · Prostaglandin synthase · Saturated fatty acid · Tumor necrosis factor alpha · Adult · Aged · Cartilage cell · Cartilage degeneration · Cell viability · Controlled study · Cytotoxicity · Enzyme release · Gene expression · Human · Human cell · Human tissue · Immunoassay · Inflammation · Limit of quantitation · Lipid transport · Reverse transcription polymerase chain reaction · Total knee replacement · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

19 Prebiotic mechanisms, functions and applications - A review
article 2013    
Author: Blatchford, P. · Ansell, J. · Godoy, M.R.C. de · Fahey, G. · Garcia-Mazcorro, J.F. · Gibson, G.R. · Goh, Y.J. · Hotchkiss, A.T. · Hutkins, R. · LaCroix, C. · Rastall, R.A. · Reimer, R.A. · Schoterman, M. · Van Sinderen, D. · Venema, K. · Whelan, K.
Keywords: Biology · Fructooligosaccharides · Galactooligosaccharides · Prebiotics · Probiotics · Mannanoligosaccharide · Oligomer · Oligosaccharide · Pectin · Prebiotic agent · Probiotic agent · Short chain fatty acid · Unclassified drug · Atopy · Bacterium culture · Biological activity · Biomass · Chelation · Citrus · Gastrointestinal tract · Gene expression · Growth stimulation · Human · Immunomodulation · Inflammatory bowel disease · Lactobacillus acidophilus · Liver injury · Metagenomics · Microbial diversity · Microbial genome · Microbiome · Microflora · Molecular weight · Mouth disease · Nonhuman · Obesity · Pyrosequencing · Respiratory tract infection · Review · RNA sequence · Skin infection · Structure activity relation · Vagina disease · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

20 Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice
article 2012    
Author: Wopereis, S. · Radonjic, M. · Rubingh, C. · Erk, M. van · Smilde, A. · Duyvenvoorde, W. van · Cnubben, N. · Kooistra, T. · Ommen, B. van · Kleemann, R.
Keywords: Biology · Diabetes mellitus Type 2 · Diabetes mellitus Type 2-prone transgenic ApoE3Leiden mice · Plasma lipidomics · White blood cell transcriptomics · acyl coA synthetase short chain family member 2 · adp ribosylation factor gtaase activating protein 1 · atp binding cassette subfamily b protein · biological marker · cytochrome c oxidase subunit vib polypeptide 2 · cytochrome P450 2B1 · fatty acid · fibroblast growth factor 16 · lipidome · seryl aminoacyl tRNA synthetase 2 · transcription elongation factor a like 8 protein · transcriptome · transferrin receptor · unclassified drug · animal cell · animal experiment · animal model · area under the curve · article · blood analysis · controlled study · disease course · gene expression · glucose intolerance · glucose tolerance test · leukocyte · lipid blood level · lipid diet · lipidomics · mouse · nonhuman · prediction · priority journal · prognosis · protein analysis · transcriptomics · Healthy for Life · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 285 found. Next | Sort by relevance