Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by relevance

1 A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease
article 2010    
Author: Eefting, D. · Seghers, L. · Grimbergen, J.M. · Vries, M.R. de · Boer, H.C. de · Lardenoye, J.W.H.P. · Jukema, J.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Health · Biomedical Research · Gene therapy · Matrix metalloproteinases · Plasmin(ogen) · Vascular surgery · Vein graft disease · apolipoprotein E3 · aprotinin · hybrid protein · matrix metalloproteinase · matrix metalloproteinase inhibitor · plasmin · plasmin inhibitor · plasminogen activator · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 1 amino terminal fragment of urokinase type plasminogen activator bovine pancreas trypsin inhibitor · unclassified drug · urokinase receptor · animal cell · animal experiment · animal model · animal tissue · article · carotid artery · cell surface · controlled study · electroporation · expression vector · female · gene overexpression · gene targeting · genetic transfection · human · human tissue · hypercholesterolemia · in vivo culture · intima · male · mouse · nonhuman · nonviral gene delivery system · priority journal · vein graft disease
[Abstract]

2 Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content
article 2009    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Verheijen, J.H. · Bockel, J.H. van · Geelkerken, R.H. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Research · antihypertensive agent · antithrombocytic agent · cystatin C · cysteine proteinase · doxycycline · gelatinase B · hydroxymethylglutaryl coenzyme A reductase inhibitor · messenger RNA · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · abdominal aorta aneurysm · adult · aged · aorta wall · article · clinical article · clinical trial · controlled clinical trial · controlled study · dose response · drug effect · drug megadose · drug tolerability · enzyme activity · enzyme assay · female · gene expression · human · human tissue · immunohistochemistry · low drug dose · male · neutrophil · polymerase chain reaction · priority journal · protein degradation · quantitative analysis · randomized controlled trial · treatment duration · Western blotting · Aged · Aged, 80 and over · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Cardiovascular Agents · Cystatin C · Cysteine Endopeptidases · Dose-Response Relationship, Drug · Doxycycline · Female · Gene Expression Regulation, Enzymologic · Humans · Male · Matrix Metalloproteinases · Middle Aged · Neutrophil Infiltration · Neutrophils · Prospective Studies · Protease Inhibitors · RNA, Messenger · Time Factors · Tissue Inhibitor of Metalloproteinase-1 · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

3 Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction
article 2009    
Author: Borne, S.W.M. van den · Cleutjens, J.P.M. · Hanemaaijer, R. · Creemers, E.E. · Smits, J.F.M. · Daemen, M.J.A.P. · Blankesteijn, W.M.
Keywords: Biology · Biomedical Research · Infarct rupture · Inflammation · Matrix metalloproteinases · MMP activity assay · MMP immunohistochemistry · Myocardial infarction · gelatinase A · gelatinase B · neutrophil collagenase · tissue inhibitor of metalloproteinase 1 · adult · aged · article · clinical article · controlled study · enzyme activity · female · heart · heart disease · heart infarction · human · human tissue · immunohistochemistry · infarct rupture · inflammatory cell · male · priority journal · zymography · Aged · Aged, 80 and over · Cell Count · Female · Heart Rupture, Post-Infarction · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Middle Aged · Myocardial Infarction · Myocarditis
[Abstract]

4 Relaxin stimulates MMP-2 and α-smooth muscle actin expression by human periodontal ligament cells
article 2008    
Author: Henneman, S. · Bildt, M.M. · Groot, J. de · Kuijpers-Jagtman, A.M. · Von den Hoff, J.W.
Keywords: Biology Nutrition · α-SMA · Fibroblasts · MMP · Periodontal ligament · Relaxin · Gelatinase · Matrix metalloproteinase · Relaxin · Tissue inhibitor of metalloproteinase · Article · Cell culture · Chemistry · Cytology · Drug effect · Enzymology · Female · Fibroblast · Gene expression · Genetics · Human · Male · Metabolism · Periodontal ligament · Cells, Cultured · Female · Fibroblasts · Gelatinases · Gene Expression · Humans · Male · Matrix Metalloproteinases · Periodontal Ligament · Relaxin · Tissue Inhibitor of Metalloproteinases
[Abstract]

5 Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers
article 2008    
Author: Meyer, F.J. · Burnand, K.G. · Abisi, S. · TeKoppele, J.M. · Els, B. van · Smith, A.
Keywords: Health · Collagen type 3 · Interstitial collagenase · Matrix metalloproteinase · Stromelysin · Peptide fragment · Clinical article · Collagen synthesis · controlled study · Enzyme activity · Leg ulcer · Priority journal · Protein analysis · Skin biopsy · Aged · Comparative study · Enzymology · Metabolism · Physiology · Varicosis · Aged · Collagen · Female · Humans · Male · Matrix Metalloproteinases · Peptide Fragments · Procollagen · Skin · Varicose Ulcer · Wound Healing
[Abstract]

6 Pericellular-acting proteases in human first trimester decidua
article 2008    
Author: Plaisier, M. · Koolwijk, P. · Willems, F. · Helmerhorst, F.M. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Decidua · First trimester · Matrix metalloproteinases · Trophoblast · UNK cells · CD56 antigen · CD68 antigen · matrix metalloproteinase · messenger RNA · proteinase · urokinase · urokinase receptor · adult · article · cell count · controlled study · decidua · female · first trimester pregnancy · gene expression · human · human cell · human tissue · immunohistochemistry · macrophage · natural killer cell · pathophysiology · pregnancy termination · priority journal · protein analysis · protein degradation · protein expression · protein function · quantitative analysis · reverse transcription polymerase chain reaction · spontaneous abortion · trophoblast · Adult · Antigens, CD · Antigens, CD56 · Antigens, Differentiation, Myelomonocytic · Decidua · Female · Humans · Immunohistochemistry · Matrix Metalloproteinase 14 · Matrix Metalloproteinase 20 · Peptide Hydrolases · Pregnancy · Pregnancy Trimester, First · Reverse Transcriptase Polymerase Chain Reaction · Healthy for Life · Healthy Living
[Abstract]

7 Contribution of collagen network features to functional properties of engineered cartilage
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Linden, J.C. van der · Zuurmond, A.M. · Weinans, H. · Verhaar, J.A.N. · Osch, G.J.V.M. van · Groot, J. de
Keywords: Health · Cartilage · Chondrocyte · Collagen · Crosslinks · Mechanical properties · 3 aminopropionitrile · alginic acid · collagen · interstitial collagenase · water · animal cell · animal cell culture · article · articular cartilage · cartilage cell · cartilage matrix · cattle · collagen degradation · controlled study · cross linking · nonhuman · priority journal · protein degradation · rigidity · tissue engineering · water retention · Alginates · Aminopropionitrile · Animals · Biomechanics · Cartilage, Articular · Cattle · Cell Count · Cells, Cultured · Chondrocytes · Extracellular Matrix · Fibrillar Collagens · Gene Expression · Matrix Metalloproteinases · Osteoarthritis · Permeability · Phenotype · Regeneration · Stress, Mechanical · Time Factors · Tissue Engineering
[Abstract]

8 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

9 Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with α2 macroglobulin in serum of rheumatoid arthritis patients
article 2008    
Author: Tchetverikov, I. · Kraan, M.C. · El, B. van · Hanemaaijer, R. · Groot, J. de · Huizinga, T.W.J.
Keywords: Biology · Biomedical Research · alpha 2 macroglobulin · C reactive protein · leflunomide · matrix metalloproteinase · methotrexate · teriflunomide · tissue inhibitor of metalloproteinase 1 · analysis · blood sampling · clinical study · complex formation · controlled study · disease activity · drug activity · drug dose increase · drug effect · drug efficacy · drug exposure · loading drug dose · major clinical study · priority journal · protein blood level · quantitative analysis · rheumatoid arthritis · serum · systemic circulation · Aged · alpha-Macroglobulins · Antirheumatic Agents · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Down-Regulation · Enzyme Inhibitors · Female · Humans · Isoxazoles · Male · Matrix Metalloproteinases · Methotrexate · Middle Aged · Multiprotein Complexes · Phenylalanine · Statistics, Nonparametric · Thiophenes
[Abstract]

10 Extracellular matrix components and regulators in the airway smooth muscle in asthma
article 2008    
Author: Araujo, B.B. · Dolhnikoff, M. · Silva, L.F.F. · Elliot, J. · Lindeman, J.H.N. · Ferreira, D.S. · Mulder, A. · Gomes, H.A.P. · Fernezlian, S.M. · James, A. · Mauad, T.
Keywords: Airway smooth muscle · Extracellular matrix · Fatal asthma · Metalloproteinases · Remodelling · Tissue inhibitor of metalloproteinase · Adolescent · Adult · Asthma · Bronchi · Case-Control Studies · Extracellular Matrix · Female · Humans · Male · Matrix Metalloproteinases · Middle Aged · Muscle, Smooth · Tissue Inhibitor of Metalloproteinases
[Abstract]

11 Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Schram, M. · Witte, T.A.M.C. · Veenendaal, R.A. · Duijn, W. van · Verheijen, J.H. · Hanemaaijer, R. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Bioactivity assay (BIA) · ELISA · Gastritis · Helicobacter pylori · Matrix metalloproteinases · MMP-2 (gelatinase A) · MMP-9 (gelatinase B) · Zymography · antibiotic agent · clarithromycin · gelatin · gelatinase A · gelatinase B · metronidazole · omeprazole · proton pump inhibitor · ranitidine · adult · aged · article · controlled study · drug activity · enzyme analysis · enzyme linked immunosorbent assay · eradication therapy · female · Helicobacter infection · Helicobacter pylori · human · major clinical study · male · priority journal · quantitative analysis · statistical significance · stomach mucosa · zymography · Adult · Aged · Anti-Infective Agents · Anti-Ulcer Agents · Biopsy · Clarithromycin · Drug Therapy, Combination · Endoscopy, Gastrointestinal · Enzyme-Linked Immunosorbent Assay · Female · Gastric Mucosa · Helicobacter Infections · Helicobacter pylori · Humans · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metronidazole · Middle Aged · Omeprazole · Ranitidine · Treatment Outcome · Helicobacter pylori
[Abstract]

12 Urinary matrix metalloproteinases reflect renal damage in anti-neutrophil cytoplasm autoantibody-associated vasculitis
article 2007    
Author: Sanders, J.S.F. · Huitema, M.G. · Hanemaaijer, R. · Goor, H. van · Kallenberg, C.G.M. · Stegeman, C.A.
Keywords: Biology · ANCA-associated vasculitis · Crescentic glomerulonephritis · Immunohistochemistry · MMP-2 · MMP-9 · Plasma levels · TIMP-1 · Urinary levels · C reactive protein · Adult · Aged · Aged, 80 and over · Antibodies, Antineutrophil Cytoplasmic · C-Reactive Protein · Creatine · Enzyme-Linked Immunosorbent Assay · Female · Humans · Immunohistochemistry · Kidney Diseases · Kidney Glomerulus · Male · Matrix Metalloproteinases · Middle Aged · Proteinuria · Tissue Inhibitor of Metalloproteinase-1 · Vasculitis
[Abstract]

13 Exposure of human cartilage tissue to low concentrations of blood for a short period of time leads to prolonged cartilage damage: An in vitro study
article 2007    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · DNA content · Blood · Blood Proteins · Cartilage, Articular · Dose-Response Relationship, Drug · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Middle Aged · Proteoglycans · Time Factors
[Abstract]

14 Collagen degradation in the abdominal aneurysm: A conspiracy of matrix metalloproteinase and cysteine collagenases
article 2007    
Author: Abdul-Hussien, H. · Soekhoe, R.G.V. · Weber, E. · Thüsen, J.H. von der · Kleemann, R. · Mulder, A. · Hajo Van Bockel, J. · Hanemaaijer, R. · Lindeman, J.H.N.
Keywords: Health · Aged · Aortic Aneurysm, Abdominal · Blotting, Western · Collagen · Collagenases · Cysteine · Female · Humans · Immunohistochemistry · Male · Matrix Metalloproteinases · Protease Inhibitors · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger
[Abstract]

15 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

16 Chemically modified tetracyclines stimulate matrix metalloproteinase-s production by periodontal ligament cells
article 2006    
Author: Bildt, M.M. · Snoek-van Beurden, A.M.P. · Groot, J. de · El, B. van · Kuijpers-Jagtman, A.M. · Hoff, J.W. van den
Keywords: Biology · Biomedical Research · Chemically modified tetracyclines · Gelatin zymography · Matrix metalloproteinases · Periodontal ligament · DNA · Enzyme inhibitor · Gelatin · Gelatinase A · Gelatinase B · Recombinant protein · Tetracycline derivative · Analysis of variance · Iosynthesis · Cell culture · Chemistry · Drug antagonism · Drug effect · Human · Metabolism · Nonparametric test · Periodontal ligament · Polyacrylamide gel electrophoresis · Western blotting · Analysis of Variance · Blotting, Western · Cells, Cultured · DNA · Electrophoresis, Polyacrylamide Gel · Enzyme Inhibitors · Gelatin · Humans · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Periodontal Ligament · Recombinant Proteins · Statistics, Nonparametric · Tetracyclines
[Abstract]

17 Pericellular proteases in angiogenesis and vasculogenesis
article 2006    
Author: Hinsbergh, V.W.M. van · Engelse, M.A. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Cathepsins · Endothelium · MT-MMPs · Neovascularization · Aminopeptidase · Angiogenic factor · Cathepsin L · Cytokine · Gelatinase A · Gelatinase B · Hemostatic agent · Hermes antigen · Matrix metalloproteinase 14 · Matrix metalloproteinase inhibitor · Pericellular proteinase · Proteinase · Serine proteinase · Unclassified drug · Urokinase · Vitronectin receptor · Accessory cell · Angiogenesis · Antiangiogenic activity · Antigen binding · Blood cell · Bone marrow cell · Cell membrane · Cell migration · Cell survival · Endothelium cell · Enzyme activity · Enzyme localization · Enzyme substrate complex · Extracellular matrix · Focal adhesion · Lamellipodium · Nonhuman · Protein degradation · Receptor binding · Vascular endothelium · ADAM Proteins · Aminopeptidases · Animals · Bone Marrow Cells · Cathepsins · Cell Differentiation · Cell Movement · Extracellular Matrix · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Mice · Neovascularization, Pathologic · Neovascularization, Physiologic · Peptide Hydrolases · Pericytes · Serine Endopeptidases · Tissue Inhibitor of Metalloproteinases
[Abstract]

18 Biochemical and functional modulation of the cartilage collagen network by IGF1, TGFβ2 and FGF2
article 2006    
Author: Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Weinans, H. · Jahr, H. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Biomedical Research · Chondrocyte · Cross-links · Growth factors · Mechanical properties · Proteoglycans · Alginic acid · Collagen fiber · Fibroblast growth factor 2 · Matrix metalloproteinase · Proteoglycan · Pyridinoline · Somatomedin C · Transforming growth factor beta2 · Animal cell · Animal tissue · Cartilage cell · Cartilage matrix · Collagen synthesis · Controlled study · Cow · Culture medium · Enzyme activity · Enzyme analysis · Nonhuman · Permeability · Protein cross linking · Protein determination · Protein function · Protein protein interaction · Rigidity · Aggrecans · Animals · Biomechanics · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type II · DNA · Extracellular Matrix · Fibroblast Growth Factor 2 · Forelimb · Gene Expression · Immunohistochemistry · Insulin-Like Growth Factor I · Matrix Metalloproteinases · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein-Lysine 6-Oxidase · Proteoglycans · Transforming Growth Factor beta2
[Abstract]

19 MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis
article 2005    
Author: Tchetverikov, I. · Lohmander, L.S. · Verzijl, N. · Huizinga, T.W.J. · TeKoppele, J.M. · Hanemaaijer, R. · Groot, J. de
Keywords: Biomedical Research · alpha 2 macroglobulin · interstitial collagenase · matrix metalloproteinase · prointerstitial collagenase · prostromelysin · stromelysin · tissue inhibitor of metalloproteinase 3 · unclassified drug · arthritis · controlled study · enzyme activation · enzyme activity · enzyme inhibition · human · immunoassay · joint injury · knee · major clinical study · osteoarthritis · priority journal · protein determination · pseudogout · quantitative analysis · synovial fluid level · Acute Disease · Adult · alpha-Macroglobulins · Arthritis · Chondrocalcinosis · Cross-Sectional Studies · Female · Humans · Knee Injuries · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

20 Involvement of Membrane-Type Matrix Metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial Cells: Role of MT3-MMP
article 2004    
Author: Plaisier, M. · Kapiteijn, K. · Koolwijk, P. · Fijten, C. · Hanemaaijer, R. · Grimbergen, J.M. · Mulder-Stapel, A. · Quax, P.H.A. · Helmerhorst, F.M. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Fibrin · Gelatinase A · Immunoglobulin G · Interstitial collagenase · Matrix metalloproteinase · Matrix metalloproteinase inhibitor · Membrane type 3 metalloproteinase · Membrane type 4 metalloproteinase · Messenger RNA · Unclassified drug · Urokinase · Adenovirus · Capillary · Cell culture · Controlled study · Endometrium cell · Endothelium cell · Enzyme inhibition · Enzyme regulation · Genetic transduction · Human cell · Immunohistochemistry · Prepuce · Protein expression · Vascular endothelium · Adenoviridae · Cells, Cultured · Collagen Type I · Endometrium · Endothelial Cells · Female · Humans · Matrix Metalloproteinase 16 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Neovascularization, Physiologic · Plasmin · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Urinary Plasminogen Activator · Adenoviridae
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by relevance