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1 Development of an enzyme-linked immunosorbent assay method to detect mustard protein in mustard seed oil
article 2007    
Author: Koppelman, S.J. · Vlooswijk, R. · Bottger, G. · Duijn, G. van · Schaft, P. van der · Dekker, J. · Bemgen, H. van
Keywords: Nutrition · Analytical research · allergen · allyl isothiocyanate · vegetable oil · vegetable protein · animal · article · Brassica · cross reaction · enzyme linked immunosorbent assay · food allergy · food analysis · human · immunology · methodology · rabbit · safety · Allergens · Animals · Consumer Product Safety · Cross Reactions · Enzyme-Linked Immunosorbent Assay · Food Analysis · Food Hypersensitivity · Humans · Mustard Plant · Plant Oils · Plant Proteins · Rabbits · Animalia · Brassica · Oryctolagus cuniculus
[Abstract]

2 The Draize Eye Test and in vitro alternatives; a left-handed marriage?
article 2006    
Author: Prinsen, M.K.
Keywords: Biology · Toxicology and Applied Pharmacology · Draize Eye Test · In vitro assay · Validation · article · draize eye test · exposure · in vitro study · nonhuman · solid · technique · validation process · Acute Toxicity Tests · Animal Testing Alternatives · Animals · Eye · Irritants · Rabbits · Reproducibility of Results

3 Cholesteryl ester transfer protein inhibition: Effect on reverse cholesterol transport?
article 2006    
Author: Rensen, P.C.N. · Havekes, L.M.
Keywords: Biology · Biomedical Research · 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester · Atorvastatin · Cholesterol ester transfer protein inhibitor · Fibric acid derivative · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Nicotinic acid · Torcetrapib · Atherosclerosis · Cholesterol transport · Clinical trial · Drug efficacy · Drug mechanism · Dyslipidemia · Editorial · Ischemic heart disease · Nonhuman · Plasma clearance · Protein expression · Reverse cholesterol transport · Animals · Biological Transport · Cardiovascular Diseases · Carrier Proteins · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Glycoproteins · Humans · Lipid Metabolism · Lipoproteins, HDL · Rabbits · Risk Factors
[Abstract]

4 Eye irritation
article 2005    
Author: Eskes, C. · Bessou, S. · Bruner, L. · Curren, R. · Harbell, J. · Jones, P. · Kreiling, R. · Liebsch, M. · McNamee, P. · Pape, W. · Prinsen, M.K. · Seidle, T. · Vanparys, P. · Worth, A. · Zuang, V.
Keywords: Biology · Toxicology and Applied Pharmacology · cosmetic · trypan blue · animal testing alternative · bovine corneal opacity and permeability assay · cell function · chicken enucleated eye test · chorioallantoic membrane vascular assay · chorioallantois · conjunctiva · cornea epithelium · cornea injury · cornea opacity · cornea permeability · cytotoxicity · enucleation · eye irritation · hemolysis · humidity · in vivo study · isolated rabbit eye test · methodology · model · nonhuman · priority journal · rabbit · review · safety · scoring system · sensor · standardization · temperature dependence · toxicity testing · validation process · Animal Testing Alternatives · Animals · Cattle · Cell Survival · Consumer Product Safety · Cosmetics · European Union · Eye · Eye Injuries · Humans · Irritants · Rabbits · Structure-Activity Relationship · Toxicity Tests · Animalia · Bovinae · Oryctolagus cuniculus

5 Embryotoxicity and teratogenicity study with α-cyclodextrin in rabbits
article 2004    
Author: Waalkens-Berendsen, D.H. · Smits-Van Prooije, A.E. · Bär, A.
Keywords: Biology · Toxicology and Applied Pharmacology · Cyclodextrin · Dietary Fiber · Lactose · Reproductive toxicity · alpha cyclodextrin · animal experiment · animal model · animal tissue · article · artificial insemination · body weight · chemical teratogenesis · controlled study · corpus luteum · diarrhea · embryotoxicity · female · fetus weight · food intake · gestational age · male · nidation · nonhuman · placenta weight · priority journal · sex ratio · sexual behavior · species comparison · teratogenicity · uterus weight · weight reduction · Abnormalities, Drug-Induced · Administration, Oral · alpha-Cyclodextrins · Animals · Cyclodextrins · Embryonic and Fetal Development · Female · Male · Pregnancy · Prenatal Exposure Delayed Effects · Rabbits · Animalia · Oryctolagus cuniculus
[Abstract]

6 Influence of inflammatory cells and serum on the performance of implantable glucose sensors
article 2001    
Author: Gerritsen, M. · Jansen, J.A. · Kros, A. · Vriezema, D.M. · Sommerdijk, N.A.J.M. · Nolte, R.J.M. · Lutterman, J.A. · Hövell, S.W.F.M. van · Gaag, A. van der
Keywords: Nutrition · Animals · Biocompatible Materials · Biosensing Techniques · Blood Glucose · Buffers · Cellulose · Coated Materials, Biocompatible · Enzymes, Immobilized · Fluorocarbon Polymers · Glucose Oxidase · Granulocytes · Inflammation · Neutrophils · Prostheses and Implants · Rabbits · Zymosan
[Abstract]

7 Simvastatin improves disturbed endothelial barrier function
article 2000    
Author: Nieuw Amerongen, G.P. van · Vermeer, M.A. · Negre-Aminou, P. · Lankelma, J. · Emeis, J.J. · Hinsbergh, V.W.M. van
Keywords: Animals · Aorta · Arteriosclerosis · Capillary Permeability · Cell Membrane Permeability · Cells, Cultured · Cholesterol · Cholesterol, LDL · Disease Models, Animal · Endothelium, Vascular · Humans · Hypercholesterolemia · Rabbits · Simvastatin
[Abstract]

8 Comparison of different immunochemical methods for the detection and quantification of hazelnut proteins in food products
article 1999    
Author: Koppelman, S. · Knulst, A.C. · Koers, W.J. · Penninks, A.H. · Peppelman, H. · Vlooswijk, R. · Pigmans, I. · Duijn, G. van · Hessing, M.
Keywords: Allergen · Detection · ELISA · Hazelnut · IgE · Immunoblotting · Food allergen · Immunoglobulin e · Rabbit antiserum · Vegetable protein · Controlled study · Enzyme linked immunosorbent assay · Food allergy · Food analysis · Food control · Food industry · Immunoblotting · Nonhuman · Polyacrylamide gel electrophoresis · Priority journal · Protein determination · Allergens · Animals · Cross Reactions · Enzyme-Linked Immunosorbent Assay · Food Analysis · Food Hypersensitivity · Humans · Immunoblotting · Immunochemistry · Immunoglobulin E · Molecular Weight · Nuts · Plant Proteins · Rabbits · Corylus · Oryctolagus cuniculus
[Abstract]

9 Instruments for oral disease-intervention strategies : recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis
article 1999    
Author: Maassen, C.B.M. · Laman, J.D. · Heijne den Bak-Glashouwer, M.J. · Tielen, F.J. · Holten-Neelen, J.C.P.A. van · Hoogteijling, L. · Antonissen, C. · Leer, R.J. · Pouwels, P.H. · Boersma, W.J.A. · Shaw, D.M.
Keywords: Experimental autoimmune/allergic encephalomyelitis (EAE) · Heterologous gene expression · Mucosal vaccines · lactobacillus vaccine · Myelin protein · Recombinant vaccine · Antibody response · Immunization · Immunoblotting · Immunogenicity · Nonhuman · Oral drug administration · Priority journal · Tetanus · Vaccination · Administration, Oral · Animals · Bacterial Vaccines · Cattle · Flow Cytometry · Genetic Vectors · Guinea Pigs · Humans · Immune Tolerance · Immunohistochemistry · Lactobacillus casei · Mice · Multiple Sclerosis · Myelin Basic Proteins · Peptide Fragments · Rabbits · Recombinant Fusion Proteins · Tetanus · Tetanus Toxin
[Abstract]

10 Embryotoxicity and teratogenicity study with y-cyclodextrin in rabbits
article 1998    
Author: Waalkens-Berendsen, D.H. · Smits-van Prooije, A.E. · Bär, A.
Keywords: gamma cyclodextrin · lactose · animal experiment · article · body weight · controlled study · diarrhea · dose response · embryotoxicity · female · fetus · fetus weight · food intake · male · nonhuman · oral drug administration · placenta weight · priority journal · rabbit · sex ratio · sexual behavior · teratogenicity · uterus weight · weight gain · Animal Feed · Animals · Body Weight · Cyclodextrins · Diarrhea · Dose-Response Relationship, Drug · Eating · Female · Fetus · gamma-Cyclodextrins · Gestational Age · Lactose · Litter Size · Male · Organ Size · Placenta · Pregnancy · Rabbits · Teratogens · Uterus · Weight Gain · Animalia · Oryctolagus cuniculus
[Abstract]

11 Assessment of side effects induced by injection of different adjuvant/antigen combinations in rabbits and mice
article 1998    
Author: Leenaars, P.P.A.M. · Koedam, M.A. · Wester, P.W. · Baumans, V. · Claassen, E. · Hendriksen, C.F.M.
Keywords: Health · Adjuvants · Distress · Immunization · Pain · Pathology · Refinement · Adjuvants, Immunologic · Animals · Antibody Formation · Antigens · Behavior, Animal · Body Temperature · Body Weight · Female · Male · Mice · Mice, Inbred BALB C · Rabbits
[Abstract]

12 Analysis of the role of the gene bipA, encoding the major endoplasmic reticulum chaperone protein in the secretion of homologous and heterologous proteins in black Aspergilli
article 1998    
Author: Punt, P.J. · Gemeren, I.A. van · Drint-Kuijvenhoven, J. · Hessing, J.G.M. · Muijlwijk van - Harteveld, G.M. · Beijersbergen, A. · Verrips, C.T. · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Binding protein · Chaperone · Glucan 1,4 alpha glucosidase · Recombinant protein · Aspergillus awamori · Aspergillus niger · Endoplasmic reticulum · Fungal genetics · Gene fusion · Gene overexpression · Nonhuman · Promoter region · Protein secretion · Animals · Antibody Specificity · Artificial Gene Fusion · Aspergillus · Aspergillus niger · Blotting, Northern · Blotting, Western · Cloning, Molecular · Fungal Proteins · Gene Expression Regulation, Fungal · Genes, Fungal · Glucan 1,4-alpha-Glucosidase · HSP70 Heat-Shock Proteins · Rabbits · Recombinant Fusion Proteins · Aspergillus · Aspergillus awamori · Aspergillus niger · Fungi
[Abstract]

13 Toxicological profile for o-benzyl-p-chlorophenol
article 1998    
Author: Stouten, H. · Bessems, J.G.M.
Keywords: Nutrition · Effects · Hazard assessment · Kinetics · o-benzo-p-chlorophenol · Review · Toxicity · chlorophenol · disinfectant agent · phenol derivative · animal experiment · animal model · carcinogenicity · cleaning · controlled study · health hazard · hospital · human · male · occupational exposure · occupational toxicology · priority journal · rat · review · toxicity · toxicology · xenobiotic metabolism · Administration, Oral · Adult · Animals · Dichlorophen · Disinfectants · Female · Housekeeping, Hospital · Humans · Male · Middle Aged · Mutagenicity Tests · Occupational Exposure · Personnel, Hospital · Rabbits · Rats · Reproduction · Skin · Tissue Distribution
[Abstract]

14 Toxicologic profile of acrylonitrile
article 1998    
Author: Woutersen, R.A.
Keywords: Carcinogenicity · Mechanism · Oral · Animal experiment · Animal model · Brain tumor · Conference paper · Genetics · Inhalation · Inhalational drug administration · Mammal · Mouse · Mouth · Nonhuman · Oral drug administration · Toxicology · Acrylonitrile · Administration, Oral · Animals · Carcinogens · Disease Models, Animal · Dogs · Guinea Pigs · Humans · Inhalation Exposure · Lethal Dose 50 · Mice · Mutagens · Rabbits · Rats · Risk Assessment · Animalia · Mammalia
[PDF] [Abstract]

15 Organotypic models for the assessment/prediction of ocular irritation
article 1997    
Author: Chamberlain, M. · Gad, S.C. · Gautheron, P. · Prinsen, M.K.
Keywords: Animal Testing Alternatives · Animals · Cattle · Cells, Cultured · Chickens · Cornea · Corneal Opacity · Eye · Eye Diseases · Irritants · Lens, Crystalline · Permeability · Predictive Value of Tests · Rabbits · Toxicity Tests
[Abstract]

16 Aggregated, conformationally changed fibrinogen exposes the stimulating sites for t-PA-catalysed plasminogen activation
article 1996    
Author: Haddeland, U. · Sletten, K. · Bennick, A. · Nieuwenhuizen, W. · Brosstad, F.
Keywords: Biology · Gel permeation chromatography · Plasminogen activation · Protein aggregation · Amino Acid Sequence · Animals · Antibodies, Monoclonal · Binding Sites · Biopolymers · Chromatography, Gel · Enzyme-Linked Immunosorbent Assay · Epitopes · Fibrinogen · Heat · Humans · Kinetics · Molecular Sequence Data · Oligopeptides · Plasminogen · Protein Conformation · Rabbits · Tissue Plasminogen Activator
[Abstract]

17 The chicken enucleated eye test (CEET) : a practical (pre)screen for the assessment of eye irritation/corrosion potential of test materials
article 1996    
Author: Prinsen, M.K.
Keywords: Toxicology · Animal Testing Alternatives · Animals · Chickens · Cornea · Corneal Opacity · Drug Evaluation, Preclinical · Epithelium · Eye Enucleation · Irritants · Rabbits · Toxicity Tests · Animalia · Gallus gallus · Oryctolagus cuniculus
[Abstract]

18 Safety evaluation of β-glucanase derived from Trichoderma reesei: Summary of toxicological data
article 1995    
Author: Coenen, T.M.M. · Schoenmakers, A.C.M. · Verhagen, H.
Keywords: Toxicology · barlican · beta glucan hydrolase · unclassified drug · animal experiment · article · chicken · chronic toxicity · controlled study · eye irritation · female · guinea pig · male · mutagenicity · nonhuman · rabbit · rat · skin irritation · skin sensitization · Administration, Oral · Animal · Animal Feed · beta-Glucosidase · Biological Products · Chickens · CHO Cells · Dermatitis, Contact · Environmental Exposure · Female · Food Additives · Guinea Pigs · Hamsters · Lethal Dose 50 · Male · Mutagenicity Tests · No-Observed-Adverse-Effect Level · Rabbits · Rats · Rats, Wistar · Salmonella typhimurium · Toxicity Tests · Trichoderma · Animalia · Cavia porcellus · Gallus gallus · Hypocrea jecorina · Oryctolagus cuniculus · Sus scrofa · Trichoderma
[Abstract]

19 Hepatocellular localisation of biosynthesis of vitronectin. Characterisation of the primary structure of rat vitronectin
article 1995    
Author: Otter, M. · Kuiper, J. · Rijken, D. · Zonneveld, A.-J. van
Keywords: Biology · cDNA · Competitive PCR · Liver · Localisation · Rat · Vitronectin · complementary dna · hemopexin · heparin binding protein · somatomedin b · vitronectin · amino acid sequence · animal cell · article · carboxy terminal sequence · cell type · consensus sequence · dna library · endothelium cell · kupffer cell · liver cell · male · nonhuman · polymerase chain reaction · protein expression · protein localization · protein synthesis · rabbit · rat · sequence homology · Amino Acid Sequence · Animals · Base Sequence · Cloning, Molecular · DNA, Complementary · Endothelium · Genetic Code · Humans · Kupffer Cells · Liver · Male · Mice · Molecular Sequence Data · Polymerase Chain Reaction · Rabbits · Rats · Sequence Homology, Amino Acid · Structure-Activity Relationship · Vitronectin
[Abstract]

20 Release of arachidonic and linoleic acid metabolites in skin organ cultures as characteristics of in vitro skin irritancy
article 1995    
Author: Sandt, J.J.M. van de · Maas, W.J.M. · Doornink, P.C. · Rutten, A.A.J.J.L.
Keywords: Biology · Animal · Animal Testing Alternatives · Arachidonic Acid · Benzalkonium Compounds · Eicosanoids · Epidermis · Female · Formaldehyde · Human · Hydroxyeicosatetraenoic Acids · In Vitro · Irritants · Linoleic Acid · Linoleic Acids · Male · Organ Culture · Rabbits · Skin · Sodium Dodecyl Sulfate · Support, Non-U.S. Gov't · Toxicity Tests
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 34 found. Next | Sort by relevance