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1 DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands
article 2009    
Author: End, C. · Bikker, F.J. · Renner, M. · Bergmann, G. · Lyer, S. · Blaich, S. · Hudler, M. · Helmke, B. · Gassler, N. · Autschbach, F. · Ligtenberg, A.J.M. · Benner, A. · Holmskov, U. · Schirmacher, P. · Nieuw Amerongen, A.V. · Rosenstiel, P. · Sina, C. · Franke, A. · Hafner, M. · Kioschis, P. · Schreiber, S. · Poustka, A. · Mollenhauer, J.
Keywords: Health · Inflammatory bowel disease · Innate immunity · Mucosal immunity · Pattern recognition · Scavenger receptor cysteine-rich · Carrageenan · Deleted in malignant brain tumors 1 · Dextran sulfate · Glycoprotein · Heparan sulfate · Lipopolysaccharide · Lipoteichoic acid · Unclassified drug · Cell surface receptor · DMBT1 protein, human · Ligand · Phosphate · Animal experiment · Animal model · Antiinflammatory activity · Antimicrobial activity · Binding competition · Cell aggregation · Colitis · Controlled study · Crohn disease · Cytotoxicity · Dose response · Enzyme linked immunosorbent assay · Escherichia coli · Experimental mouse · Host pathogen interaction · Human · Human cell · In vitro study · Innate immunity · Intestine epithelium cell · Mouse · Nonhuman · Protein binding · Protein determination · Protein expression · Protein function · Protein motif · Protein phosphorylation · Salmonella minnesota · Salmonella typhimurium · Streptococcus gordonii · Sulfation · Bacterium · Cell line · Drug antagonism · Epithelium cell · Genetics · Immunology · Intestine · Metabolism · Microbiology · Bacteria · Carrageenan · Cell Line · Dextran Sulfate · Epithelial Cells · Humans · Intestines · Ligands · Phosphates · Receptors, Cell Surface
[Abstract]

2 Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
article 2007    
Author: Fabriek, B.O. · Møller, H.J. · Vloet, R.P.M. · Winsen, L.M. van · Hanemaaijer, R. · Teunissen, C.E. · Uitdehaag, B.M.J. · Berg, T.K. van den · Dijkstra, C.D.
Keywords: Health · Biomedical Research · CD163 · Metalloproteinase · Monocytes · Multiple sclerosis · Scavenger receptor · sCD163 · CD163 antigen · cytokine · gelatinase B · scavenger receptor · adult · aged · analytic method · article · comparative study · controlled study · cytokine production · down regulation · enzyme activity · female · human · major clinical study · male · multiple sclerosis · priority journal · protein degradation · upregulation · Adolescent · Adult · Aged · Aged, 80 and over · Animals · Antigens, CD · Antigens, Differentiation, Myelomonocytic · Cell Line, Transformed · Cricetinae · Cricetulus · Cytokines · Enzyme Inhibitors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydrocortisone · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Middle Aged · Multiple Sclerosis · Receptors, Cell Surface · Statistics, Nonparametric · Transfection
[Abstract]

3 Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells
article 2005    
Author: Verwei, M. · Berg, H. van den · Havenaar, R. · Groten, J.P.
Keywords: Biology · Biomedical Research · Bioavailability · Caco-2 · Folate · Folate-binding protein · Intestinal transport · 5 methyltetrahydrofolic acid · caffeine · folate binding protein · folic acid · mannitol · article · cell growth · cell membrane permeability · controlled study · human · human cell · intestine absorption · intestine cell · monolayer culture · protein binding · Biological Transport · Caco-2 Cells · Carrier Proteins · Cell Culture Techniques · Chromatography, Gel · Folic Acid · Humans · Intestinal Absorption · Intestine, Small · Receptors, Cell Surface · Tetrahydrofolates · Time Factors · Bovinae
[Abstract]

4 Bioavailability of folic acid from fortified pasteurised and UHT-treated milk in humans
article 2005    
Author: Jong, R.J. de · Verwei, M. · West, C.E. · Vliet, T. van · Siebelink, E. · Berg, H. van den · Castenmiller, J.J.M.
Keywords: Health Chemistry · Biomedical Research · Bioavailability · Folate-binding proteins · Folic acid · Fortified milk · Homocysteine · Humans · folate binding protein · folic acid · homocysteine · placebo · adult · article · bioavailability · blood level · clinical trial · concentration (parameters) · controlled clinical trial · controlled study · denaturation · diet supplementation · dietary intake · double blind procedure · erythrocyte level · female · food composition · high temperature · human · human experiment · male · milk · normal human · protein binding · randomized controlled trial · treatment outcome · volunteer · Adolescent · Adult · Animals · Biological Availability · Carrier Proteins · Double-Blind Method · Erythrocytes · Female · Folic Acid · Food Handling · Food, Fortified · Homocysteine · Humans · Male · Middle Aged · Milk · Neural Tube Defects · Receptors, Cell Surface
[Abstract]

5 The Binding of Folic Acid and 5-Methyltetrahydrofolate to Folate-Binding Proteins during Gastric Passage Differs in a Dynamic in Vitro Gastrointestinal Model
article 2004    
Author: Verwei, M. · Arkbåge, K. · Mocking, H. · Havenaar, R. · Groten, J.
Keywords: Biology · Physiological Sciences · 5-Methyltetrahydrofolate · Folate-binding protein · Folic acid · Gastric passage · Milk products · 5 methyltetrahydrofolic acid · folate binding protein · folic acid · absorption · article · dairy product · duodenum · dynamics · food intake · gastrointestinal tract · in vitro study · milk level · model · nonhuman · protein binding · simulation · vitamin supplementation · Animals · Carrier Proteins · Chromatography, Gel · Duodenum · Folic Acid · Food, Fortified · Gastrointestinal Transit · Humans · Milk · Milk Proteins · Models, Biological · Protein Binding · Receptors, Cell Surface · Tetrahydrofolates
[Abstract]

6 Toll-Like Receptor 4 Is Involved in Outward Arterial Remodeling
article 2004    
Author: Hollestelle, S.C.G. · Vries, M.R. de · Keulen, J.K. van · Schoneveld, A.H. · Vink, A. · Strijder, C.F. · Middelaar, B.J. van · Pasterkamp, G. · Q́uax, P.H.A. · Kleijn, D.P.V. de
Keywords: Arteries · Plaque · Proteins · Remodeling · apolipoprotein E3 · fibronectin · heat shock protein 60 · ligand · lipopolysaccharide · messenger RNA · angiogenesis · animal experiment · animal model · animal tissue · artery diameter · atherosclerotic plaque · blood vessel remodeling · carotid artery ligation · controlled study · femoral artery · immunohistochemistry · intima · male · mouse · nonhuman · priority journal · reverse transcription polymerase chain reaction · tissue structure · transgenic mouse · Western blotting · Animals · Apolipoprotein E3 · Apolipoproteins E · Arteries · Arteriosclerosis · Carotid Arteries · Female · Femoral Artery · Ligands · Membrane Glycoproteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Cell Surface · Toll-Like Receptor 4 · Toll-Like Receptors
[Abstract]

7 Bioaccessibility of Folic Acid and (6S)-5-Methyltetrahydrofolate Decreases after the Addition of Folate-Binding Protein to Yogurt as Studied in a Dynamic in Vitro Gastrointestinal Model
article 2003    
Author: Arkbåge, K. · Verwei, M. · Havenaar, R. · Witthöft, C.
Keywords: Health · Physiological Sciences · Folate bioaccessibility · Folate-binding protein · In vitro gastrointestinal model · Pasteurized milk · Yogurt · 5 methyltetrahydrofolic acid · folate binding protein · folic acid · yoghurt · article · bioavailability · food composition · food processing · milk · pasteurization · protein binding · Animals · Biological Availability · Carrier Proteins · Digestive Physiology · Digestive System · Folic Acid · Intestinal Mucosa · Jejunum · Milk · Models, Biological · Receptors, Cell Surface · Tetrahydrofolates · Yogurt
[Abstract]

8 Broad expression of Toll-like receptors in the human central nervous system
article 2002    
Author: Bsibsi, M. · Ravid, R. · Gveric, D. · Noort, J.M. van
Keywords: Health · Central nervous system · Oligodendrocytes · Toll-like receptors · Toll like receptor · Unclassified drug · Alzheimer disease · Cell vacuole · Controlled study · Human tissue · Immunocytochemistry · Parkinson disease · Pick presenile dementia · Protein expression · Aged · Aged, 80 and over · Astrocytes · Cells, Cultured · Central Nervous System · Central Nervous System Infections · Drosophila Proteins · Encephalitis · Female · Gene Expression Regulation · Humans · Immune System · Immunohistochemistry · Male · Membrane Glycoproteins · Microglia · Middle Aged · Multiple Sclerosis · Neuroglia · Oligodendroglia · Receptors, Cell Surface · RNA, Messenger · Toll-Like Receptor 2 · Toll-Like Receptor 3 · Toll-Like Receptor 4 · Toll-Like Receptors
[Abstract]

9 Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1
article 2002    
Author: Lamfers, M.L.M. · Grimbergen, J.M. · Aalders, M.C. · Havenga, M.J. · Vries, M.R. de · Huisman, L.G.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Biology · Adenovirus · Matrix metalloproteinases · Neointima formation · Plasmin(ogen) · Urokinase-type plasminogen activator · Adenovirus · Adenoviridae · Animals · Cell Division · Cell Membrane · Cell Movement · Cells, Cultured · CHO Cells · Collagenases · Cricetinae · Culture Media, Conditioned · Enzyme Activation · Flow Cytometry · Gene Transfer Techniques · Humans · Matrix Metalloproteinase 13 · Muscle, Smooth, Vascular · Protein Structure, Tertiary · Receptors, Cell Surface · Recombinant Fusion Proteins · RNA, Messenger · Saphenous Vein · Tissue Inhibitor of Metalloproteinase-1 · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

10 Proteolysis of the urokinase-type plasminogen activator receptor by metalloproteinase-12: Implication for angiogenesis in fibrin matrices
article 2001    
Author: Koolwijk, P. · Sidenius, N. · Peters, E. · Sier, C.F.M. · Hanemaaijer, R. · Blasi, F. · Hinsbergh, V.W.M. van
Keywords: Binding Sites · Blotting, Western · Cells, Cultured · Endothelium, Vascular · Fibrin · Fibroblast Growth Factor 2 · Gene Expression · Humans · Metalloendopeptidases · Microcirculation · Neovascularization, Physiologic · Phenylalanine · Protease Inhibitors · Receptors, Cell Surface · Recombinant Proteins · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Thiophenes · Transfection · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

11 Urokinase receptor expression on human microvascular endothelial cells is increased by hypoxia: Implications for capillary-like tube formation in a fibrin matrix
article 2000    
Author: Kroon, M.E. · Koolwijk, P. · Vecht, B. van der · Hinsbergh, V.W.M. van
Keywords: Anoxia · Antigens, CD · Cell Hypoxia · Cell Survival · Cells, Cultured · Culture Media · Culture Media, Conditioned · DNA, Complementary · Endothelial Growth Factors · Endothelium, Vascular · Extracellular Matrix · Fibrin · Fibroblast Growth Factor 2 · Gene Expression Regulation · Human · Integrin alphaV · Integrins · Lymphokines · Morphogenesis · Neovascularization, Pathologic · Oxygen · Plasmin · Proto-Oncogene Proteins · Receptor Protein-Tyrosine Kinases · Receptors, Cell Surface · Receptors, Growth Factor · Receptors, Vascular Endothelial Growth Factor · Receptors, Vitronectin · RNA, Messenger · Support, Non-U.S. Gov't · Tumor Necrosis Factor · Urinary Plasminogen Activator · Vascular Endothelial Growth Factor Receptor-1
[Abstract]

12 Binding and transfer of verocytotoxin by polymorphonuclear leukocytes in hemolytic uremic syndrome
article 2000    
Author: Loo, D.M.W.M. te · Monnens, L.A.H. · Velden, T.J.A.M. van der · Vermeer, M.A. · Preyers, F. · Demacker, P.N.M. · Heuvel, L.P.W.J. van den · Hinsbergh, V.W.M. van
Keywords: Biology · Adult · Bacterial Toxins · Child · Endothelium, Vascular · Escherichia coli · Fluorescein-5-isothiocyanate · Hemolytic-Uremic Syndrome · Humans · Iodine Radioisotopes · Kidney Glomerulus · Kinetics · Lipoproteins · Lipoproteins, HDL · Lipoproteins, LDL · Lipoproteins, VLDL · Microcirculation · Neutrophils · Receptors, Cell Surface · Shiga-Like Toxin I · Trihexosylceramides
[Abstract]

13 Increased clearance explains lower plasma levels of tissue-type plasminogen activator by estradiol: Evidence for potently enhanced mannose receptor expression in mice
article 1999    
Author: Lansink, M. · Jong, M. · Bijsterbosch, M. · Bekkers, M. · Toet, K. · Havekes, L. · Emeis, J. · Kooistra, T.
Keywords: Biology · Animals · Endothelium, Vascular · Estradiol Congeners · Ethinyl Estradiol · Fibrinolysis · Humans · Lectins, C-Type · Liver · Mannose-Binding Lectins · Mice · Rats · Receptors, Cell Surface · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

14 Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator
article 1999    
Author: Sitter, T. · Toet, K. · Quax, P. · Kooistra, T.
Keywords: Antibodies · Biological Transport, Active · Carrier Proteins · Cells, Cultured · Chloroquine · Culture Media, Conditioned · Epithelial Cells · Fibrinolysis · Gene Expression · Glutathione Transferase · Humans · Iodine Radioisotopes · LDL-Receptor Related Protein 1 · Lectins, C-Type · Mannose-Binding Lectins · Plasminogen Activator Inhibitor 1 · Receptors, Cell Surface · Receptors, Immunologic · Receptors, LDL · Recombinant Fusion Proteins · RNA, Messenger · Tissue Plasminogen Activator · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

15 Mitogenic effects of urokinase on melanoma cells are independent of high affinity binding to the urokinase receptor
article 1998    
Author: Koopman, J.L. · Slomp, J. · Bart, A.C.W. de · Quax, P.H.A. · Verheijent, J.H.
Keywords: Health · Cell Division · Humans · Melanoma · Mitogens · Plasminogen Activator Inhibitor 1 · Protein Binding · Receptors, Cell Surface · Signal Transduction · Tissue Plasminogen Activator · Tumor Cells, Cultured · Urinary Plasminogen Activator · Escherichia coli · Rickettsia sp. PAR
[PDF] [Abstract]

16 Binding of human urokinase-type plasminogen activator to its receptor : Residues involved in species specificity and binding
article 1998    
Author: Quax, P.H.A. · Grimbergen, J.M. · Lansink, M. · Bakker, A.H.F. · Blatter, M.C. · Belin, D. · Hinsbergh, V.W.M. van · Verheijen, J.H.
Keywords: Health · Site-directed mutagenesis · Urokinase-type plasminogen activator · Urokinase-type plasminogen activator receptor · Amino Acid Sequence · Animals · Asparagine · Binding, Competitive · Cells, Cultured · Cricetinae · Endothelium, Vascular · Humans · Ligands · Mice · Molecular Sequence Data · Mutagenesis, Site-Directed · Receptors, Cell Surface · Sequence Homology, Amino Acid · Species Specificity · Swine · Tyrosine · Urinary Plasminogen Activator
[Abstract]

17 Effect of steroid hormones and retinoids on the formation of capillary-like tubular structures of human microvascular endothelial cells in fibrin matrices is related to urokinase expression
article 1998    
Author: Lansink, M. · Koolwijk, P. · Hinsbergh, V. van · Kooistra, T.
Keywords: Health · Aprotinin · Calcitriol · Capillaries · Cell Culture Techniques · Cells, Cultured · Drug Interactions · Endothelium, Vascular · Extracellular Matrix · Fibrin · Fibroblast Growth Factor 2 · Gene Expression Regulation · Gonadal Steroid Hormones · Humans · Male · Morphogenesis · Neovascularization, Physiologic · Plasmin · Polymerase Chain Reaction · Receptors, Cell Surface · Receptors, Retinoic Acid · Receptors, Steroid · Retinoids · RNA, Messenger · Steroids · Tissue Plasminogen Activator · Triiodothyronine · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

18 Tumor necrosis factor-α regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells
article 1998    
Author: Giraudo, E. · Primo, L. · Audero, E. · Gerber, H.-P. · Koolwijk, P. · Soker, S. · Klagsbrun, M. · Ferrara, N. · Bussolino, F.
Keywords: Antigens, Surface · Cells, Cultured · Endothelium, Vascular · Gene Expression Regulation · Humans · Kinetics · Membrane Glycoproteins · Nerve Tissue Proteins · Neuropilin-1 · Receptor Protein-Tyrosine Kinases · Receptors, Cell Surface · Receptors, Growth Factor · Receptors, Vascular Endothelial Growth Factor · RNA, Messenger · Tumor Necrosis Factor-alpha · Up-Regulation · Wound Healing
[PDF] [Abstract]

19 Inhibition of mannose receptor-mediated-clearance of tissue-type plasminogen activator (t-PA) by dextran : A new explanation for its antithrombotic effect
article 1997    
Author: Noorman, F. · Barrett-Bergshoeff, M.M. · Bekkers, M. · Emeis, J.J. · Rijken, D.C.
Keywords: Biology · Anticoagulant agent · Dextran · Dextran 40 · Dextran 70 · Low density lipoprotein receptor · Mannose receptor · Tissue plasminogen activator · Animal experiment · Bolus injection · Controlled study · Deep vein thrombosis · Drug infusion · Drug mechanism · Human · Human cell · Macrophage · Male · Monocyte · Nonhuman · Plasma clearance · Priority journal · Protein blood level · Rat · Thrombogenesis · Acetylgalactosamine · Animals · Cells, Cultured · Depression, Chemical · Dextrans · Fibrinolytic Agents · Glucose · Humans · Lectins, C-Type · Macrophages · Male · Mannose · Mannose-Binding Lectins · Metabolic Clearance Rate · Protein Binding · Rats · Rats, Wistar · Receptors, Cell Surface · Receptors, LDL · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

20 Monoclonal antibodies against the human mannose receptor that inhibit the binding of tissue-type plasminogen activator
article 1997    
Author: Barrett-Bergshoeff, M.M. · Moorman, F. · Bos, R. · Rijken, D.C.
Keywords: Biology · Antibodies, Monoclonal · Antigen-Antibody Reactions · Blotting, Western · Enzyme-Linked Immunosorbent Assay · Epitopes · Flow Cytometry · Humans · Immunohistochemistry · Lectins, C-Type · Macrophages · Mannose-Binding Lectins · Placenta · Receptors, Cell Surface · Tissue Plasminogen Activator
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 32 found. Next | Sort by relevance