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1 The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the α2-adrenergic receptors in beta cells
article 2010    
Author: Leeuw van Weenen, J.E. de · Parlevliet, E.T. · Maechler, P. · Havekes, L.M. · Romijn, J.A. · Ouwens, D.M. · Pijl, H. · Guigas, B.
Keywords: Biology · Biomedical Research · α2-Adrenergic receptor · Bromocriptine · Dopamine receptor · INS-1E cells · Insulin secretion · Mice · alpha 2 adrenergic receptor · bromocriptine · cyclic AMP · domperidone · dopamine 2 receptor stimulating agent · G protein coupled receptor · glucose · insulin · placebo · yohimbine · analytic method · animal cell · animal experiment · article · cell line · cell membrane depolarization · cell membrane potential · controlled study · drug effect · glucose clamp technique · glucose tolerance test · hyperglycemia · in vitro study · in vivo study · inhibition kinetics · insulin release · male · mouse · nonhuman · pancreas islet beta cell · priority journal · Western blotting · Animals · Bromocriptine · Cell Line · Dopamine Agonists · Dose-Response Relationship, Drug · Glucose · Insulin · Insulin-Secreting Cells · Insulinoma · Male · Mice · Mice, Inbred C57BL · Rats · Receptors, Adrenergic, alpha · Receptors, Dopamine D2
[Abstract]

2 Tailoring fiber diameter in electrospun poly(ε-Caprolactone) scaffolds for optimal cellular infiltration in cardiovascular tissue engineering
article 2009    
Author: Balguid, A. · Mol, A. · Marion, M.H. van · Bank, R.A. · Bouten, C.V.C. · Baaijens, F.P.T.
Keywords: Biology · Biomedical Research · 4-hydroxybutyrate · Average fiber diameters · Caprolactone · Cardiovascular tissue engineerings · Cell attachments · Cell deliveries · Cell distributions · Cell ingrowths · Cell migrations · Cell penetrations · Cell sizes · Cellular infiltrations · Crucial parameters · Electrospun · Fiber diameters · Homogeneous tissues · Myofibroblasts · Nanofibrous scaffolds · Poly(glycolic acid) · Sufficient matrixes · Applications · Cell culture · Cells · Fibers · Tissue engineering · Scaffolds · polycaprolactone · polyglycolic acid · tissue scaffold · article · cell infiltration · cell membrane permeability · cell transport · cellular distribution · controlled study · fiber · human · human cell · human cell culture · myofibroblast · priority journal · tissue engineering · vein
[Abstract]

3 Retrospective detection of sulfur mustard exposure by mass spectrometric analysis of adducts to albumin and hemoglobin: An in vivo study
article 2008    
Author: Noort, D. · Fidder, A. · Degenhardt-Langelaan, C.E.A.M. · Hulst, A.G.
Keywords: Albumin · Alkylation · Animal experiment · Article · Blood analysis · Cell membrane · Chemical reaction · Controlled study · Environmental exposure · Erythrocyte · In vivo study · Nonhuman · Alkylation · Animals · Affinity chromatography · Liquid chromatography · Environmental exposure · Environmental monitoring · Injections, Intravenous · Male · Pronase · Rats · Wistar · Mass spectrometry · Electrospray ionization · Tandem mass spectrometry · Rattus · Hemoglobin 9008-02-0 · Mustard gas 505-60-2 · Biological markers · Hemoglobins · Pronase, EC 3.4.24.- · Serum albumin
[Abstract]

4 Aspergillus niger genome-wide analysis reveals a large number of novel alpha-glucan acting enzymes with unexpected expression profiles
article 2008    
Author: Yuan, X.-L. · Kaaij, R.M. van der · Hondel, C.A.M.J.J. van den · Punt, P.J. · Maarel, M.J.E.C. van der · Dijkhuizen, L. · Ram, A.F.J.
Keywords: Biology · Alpha-amylase · Alpha-glucan · Alpha-glucosidase · AmyR · Aspergillus niger · Cell wall · Glucoamylase · Maltose · Starch · Starch-binding domain · 1,4 alpha glucan branching enzyme · alpha glucosidase · amylase · cell enzyme · cell membrane protein · fungal protein · glucan 1,4 alpha glucosidase · glycosidase · glycosylphosphatidylinositol · maltose · protein amyr · starch · article · Aspergillus niger · carbohydrate metabolism · carbon source · controlled study · degradation · energy resource · enzymatic degradation · enzyme synthesis · gene expression profiling · gene identification · gene sequence · genetic transcription · genome analysis · microarray analysis · nonhuman · nucleotide sequence · priority journal · transcription regulation · alpha-Amylase · alpha-Glucosidases · Amino Acid Sequence · Aspergillus niger · Base Sequence · Conserved Sequence · Fungal Proteins · Gene Expression Profiling · Gene Expression Regulation, Fungal · Genome, Fungal · Genomics · Glucan 1,4-alpha-Glucosidase · Glycoside Hydrolases · Maltose · Molecular Sequence Data · Phylogeny · Trans-Activators · Transcription, Genetic · Aspergillus niger · Fungi
[Abstract]

5 Transcriptome analysis of sorbic acid-stressed Bacillus subtilis reveals a nutrient limitation response and indicates plasma membrane remodeling
article 2008    
Author: Beek, A. ter · Keijser, B.J.F. · Boorsma, A. · Zakrzewska, A. · Orij, R. · Smits, G.J. · Brul, S.
Keywords: Biology · Biotechnology · cerulenin · sorbic acid · tricarboxylic acid · acidity · article · Bacillus subtilis · bacterial gene · bacterial genome · bacterial growth · bkdr regulated gene · ccpa gene · cell membrane · codY gene · fag bene · fur gene · genetic transcription · growth inhibition · nonhuman · nutrient limitation · priority journal · regulon · sigh mediated gene · sigl mediated gene · sporogenesis · transcriptomics · upregulation · Anions · Bacillus subtilis · Bacterial Proteins · Cell Membrane · Cerulenin · Gene Expression Profiling · Gene Expression Regulation, Bacterial · Hydrogen-Ion Concentration · Oligonucleotide Array Sequence Analysis · Regulon · Reverse Transcriptase Polymerase Chain Reaction · Sorbic Acid · Bacillus subtilis
[Abstract]

6 An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers
article 2006    
Author: Schutte, M.E. · Freidig, A.P. · Sandt, J.J.M. van de · Alink, G.M. · Rietjens, I.M.C.M. · Groten, J.P.
Keywords: Biology · Biomedical Research · ABC transporter · Caco-2 · Flavonoid · Heterocyclic amine · In silico · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · breast cancer resistance protein · chrysoeriol · elacridar · flavone · flavonoid · kaempferol · luteolin · morin · multidrug resistance protein · myricetin · naringenin · quercetin · robinetin · taxifolin · unclassified drug · verlukast · absorption · apical membrane · article · cell strain CACO 2 · computer model · controlled study · drug effect · human · human cell · Acridines · ATP-Binding Cassette Transporters · Biological Transport, Active · Caco-2 Cells · Carcinogens · Cell Membrane Permeability · Diffusion · Dose-Response Relationship, Drug · Flavanones · Flavonoids · Humans · Imidazoles · Intestinal Absorption · Intestinal Mucosa · Kinetics · Membrane Transport Proteins · Models, Biological · Multidrug Resistance-Associated Proteins · Neoplasm Proteins · P-Glycoprotein · Propionates · Quinolines · Reproducibility of Results · Tetrahydroisoquinolines
[Abstract]

7 Pericellular proteases in angiogenesis and vasculogenesis
article 2006    
Author: Hinsbergh, V.W.M. van · Engelse, M.A. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Cathepsins · Endothelium · MT-MMPs · Neovascularization · Aminopeptidase · Angiogenic factor · Cathepsin L · Cytokine · Gelatinase A · Gelatinase B · Hemostatic agent · Hermes antigen · Matrix metalloproteinase 14 · Matrix metalloproteinase inhibitor · Pericellular proteinase · Proteinase · Serine proteinase · Unclassified drug · Urokinase · Vitronectin receptor · Accessory cell · Angiogenesis · Antiangiogenic activity · Antigen binding · Blood cell · Bone marrow cell · Cell membrane · Cell migration · Cell survival · Endothelium cell · Enzyme activity · Enzyme localization · Enzyme substrate complex · Extracellular matrix · Focal adhesion · Lamellipodium · Nonhuman · Protein degradation · Receptor binding · Vascular endothelium · ADAM Proteins · Aminopeptidases · Animals · Bone Marrow Cells · Cathepsins · Cell Differentiation · Cell Movement · Extracellular Matrix · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Mice · Neovascularization, Pathologic · Neovascularization, Physiologic · Peptide Hydrolases · Pericytes · Serine Endopeptidases · Tissue Inhibitor of Metalloproteinases
[Abstract]

8 Response of apolipoprotein E*3-Leiden transgenic mice to dietary fatty acids: Combining liver proteomics with physiological data
article 2005    
Author: Roos, B. de · Duivenvoorden, I. · Rucklidge, G. · Reid, M. · Ross, K. · Lamers, R.J.A.N. · Voshol, P.J. · Havekes, L.M. · Teusink, B.
Keywords: Biology · Biomedical Research · Conjugated linoleic acid · Elaidic acid · Fenofibrate · Glucose · Liver protein · Membrane protein · Animal model · Atherosclerosis · Controlled study · Diet · Diet therapy · Fat intake · Fatty acid oxidation · Glucose metabolism · Insulin resistance · Ischemic heart disease · Lipoprotein metabolism · Metabolic syndrome X · Mouse · Nonhuman · Principal component analysis · Structural proteomics · Transgenic mouse · 3-Hydroxybutyric Acid · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Blood Glucose · Cell Membrane · Cholesterol · Cytosol · Dietary Fats · Disease Models, Animal · Electrophoresis, Gel, Two-Dimensional · Fatty Acids · Female · Fish Oils · Insulin · Linoleic Acids, Conjugated · Lipid Metabolism · Lipids · Liver · Mice · Mice, Transgenic · Oleic Acid · Organ Size · Proteins · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Triglycerides · Animalia · Mus musculus

9 Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells
article 2005    
Author: Verwei, M. · Berg, H. van den · Havenaar, R. · Groten, J.P.
Keywords: Biology · Biomedical Research · Bioavailability · Caco-2 · Folate · Folate-binding protein · Intestinal transport · 5 methyltetrahydrofolic acid · caffeine · folate binding protein · folic acid · mannitol · article · cell growth · cell membrane permeability · controlled study · human · human cell · intestine absorption · intestine cell · monolayer culture · protein binding · Biological Transport · Caco-2 Cells · Carrier Proteins · Cell Culture Techniques · Chromatography, Gel · Folic Acid · Humans · Intestinal Absorption · Intestine, Small · Receptors, Cell Surface · Tetrahydrofolates · Time Factors · Bovinae
[Abstract]

10 Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi α-subunits
article 2004    
Author: Klaasse, E. · Ligt, R.A.F.de · Roerink, S.F. · Lorenzen, A. · Milligan, G. · Leurs, R. · IJzerman, A.P.
Keywords: Health · Physiological Sciences · Adenosine A1 receptor · Allosteric modulation · Constitutive activity · Fusion protein · G protein · Inverse agonism · 2 amino 4,5 dimethyl 3 (3 trifluoromethylbenzoyl)thiophene · 6 n cyclopentyladenosine · 8 cyclopentyl 1,3 dipropylxanthine · 8 cyclopentyltheophylline · Adenosine A1 receptor · Amino acid · Arginine · Cysteine · Glycine · Guanine nucleotide binding protein · Guanosine 5' o (3 thiotriphosphate) · Histidine · Hybrid protein · Isoleucine · Phenylalanine · Proline · Radioligand · Serine · Sodium ion · Sulfur 35 · Valine · Allosterism · Alpha chain · Animal cell · Cercopithecidae · Ligand binding · Nonhuman · Priority journal · Protein analysis · Adenosine · Allosteric Site · Animals · Binding, Competitive · Cell Membrane · COS Cells · Cysteine · Dose-Response Relationship, Drug · GTP-Binding Protein alpha Subunits, Gi-Go · Guanosine 5'-O-(3-Thiotriphosphate) · Humans · Mutation · Radioligand Assay · Receptor, Adenosine A1 · Recombinant Fusion Proteins · Sodium Chloride · Sulfur Radioisotopes · Thiophenes · Transfection · Tritium · Xanthines
[Abstract]

11 Physicochemical properties and transport of steroids across Caco-2 cells
article 2003    
Author: Faassen, F. · Kelder, J. · Lenders, J. · Onderwater, R. · Vromans, H.
Keywords: Drugs · Physiological Sciences · Absorption · Caco-2 permeability · Physicochemical properties · Steroids · 17alpha hydroxy 11 methylene 19 norpregna 4,15 dien 20 yn 3 one · aldosterone · cefalexin · cortisone · dexamethasone · estradiol · ethinylestradiol · etonogestrel · gestodene · glucose · hydrocortisone · macrogol 4000 · mannitol · nandrolone · norethisterone · norgestrel · org 32540 · org 34694 · org 36410 · org 4060 · org 4325 · org om 08 · phenazone · prednisolone · progesterone · spironolactone · steroid · testosterone · verapamil · article · calculation · cell membrane permeability · cell strain CACO 2 · controlled study · drug absorption · drug surveillance program · drug transport · human · human cell · molecular weight · physical chemistry · priority journal · Biological Transport · Caco-2 Cells · Chemistry, Physical · Humans · Solubility · Steroids
[Abstract]

12 Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: Comparison of active and passive transport with the human colon carcinoma Caco-2 cell line
article 2002    
Author: Versantvoort, C.H.M. · Ondrewater, R.C.A. · Duizer, E. · Sandt, J.J.M. van de · Gilde, A.J. · Groten, J.P.
Keywords: Caco-2 · Carrier-mediated transport · H+-di/tripeptide carrier · IEC-18 · Intestinal cell lines · MRP · P-Glycoprotein · acetylsalicylic acid · calcein · carrier protein · dinitrophenylglutathione · glucose derivative · glutathione derivative · glycoprotein P · glycylsarcosine · hydrocortisone · macrogol 4000 · mannitol · methylglucose · multidrug resistance protein · probenecid · propranolol · rhodamine 123 · salicylic acid · testosterone · unclassified drug · verapamil · vincristine · animal cell · article · cell membrane permeability · cell strain CACO 2 · cell transport · colon carcinoma · controlled study · drug transport · human · human cell · in vitro study · ion transport · model · nonhuman · priority journal · protein expression · rat · screening
[Abstract]

13 Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1
article 2002    
Author: Lamfers, M.L.M. · Grimbergen, J.M. · Aalders, M.C. · Havenga, M.J. · Vries, M.R. de · Huisman, L.G.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Biology · Adenovirus · Matrix metalloproteinases · Neointima formation · Plasmin(ogen) · Urokinase-type plasminogen activator · Adenovirus · Adenoviridae · Animals · Cell Division · Cell Membrane · Cell Movement · Cells, Cultured · CHO Cells · Collagenases · Cricetinae · Culture Media, Conditioned · Enzyme Activation · Flow Cytometry · Gene Transfer Techniques · Humans · Matrix Metalloproteinase 13 · Muscle, Smooth, Vascular · Protein Structure, Tertiary · Receptors, Cell Surface · Recombinant Fusion Proteins · RNA, Messenger · Saphenous Vein · Tissue Inhibitor of Metalloproteinase-1 · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

14 One repeat of the cell wall binding domain is sufficient for anchoring the Lactobacillus acidophilus surface layer protein
article 2002    
Author: Smit, E. · Pouwels, P.H.
Keywords: Health · Cell membrane protein · Sac1 protein · Unclassified drug · Vitronectin · Amino terminal sequence · Bacterial cell wall · Bacterial genetics · Bacterium adherence · Carboxy terminal sequence · Controlled study · Nonhuman · Protein domain · Bacterial Proteins · Cell Wall · Disinfectants · Lactobacillus acidophilus · Membrane Glycoproteins · Membrane Proteins · Phenol · Protein Binding · Protein Structure, Tertiary · Sonication · Actinobacteria (class) · Bacteria (microorganisms) · Lactobacillus · Lactobacillus acidophilus · Uncultured actinomycete
[PDF] [Abstract]

15 Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
article 2002    
Author: Kuenen, B.C. · Levi, M. · Meijers, J.C.M. · Kakkar, A.K. · Hinsbergh, V.W.M. van · Kostense, P.J. · Pinedo, H.M. · Hoekman, K.
Keywords: Angiogenesis Inhibitors · Blood Coagulation · Blood Platelets · Carcinoma, Renal Cell · Cell Division · Cell Membrane Permeability · Cell Movement · Drug Administration Schedule · Endothelium, Vascular · Fibrinolysis · Hemostasis · Indoles · Kidney Neoplasms · Melanoma · Neovascularization, Pathologic · Protein C · Proto-Oncogene Proteins · Pyrroles · Receptor Protein-Tyrosine Kinases · Receptors, Growth Factor · Receptors, Vascular Endothelial Growth Factor · Sarcoma · Thrombin · Vascular Endothelial Growth Factor Receptor-1
[Abstract]

16 Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine
article 2001    
Author: Peschel, A. · Jack, R.W. · Otto, M. · Collins, L.V. · Staubitz, P. · Nicholson, G. · Kalbacher, H. · Nieuwenhuizen, W.F. · Jung, G. · Tarkowski, A. · Kessel, K.P.M. van · Strijp, J.A.G. van
Keywords: Toxicology · Host defense peptides · Innate immunity · Oxygen-independent killing · Phospholipids · Staphylococcus aureus virulence · antibiotic agent · defensin · gallidermin · gramicidin D · gramicidin S · lysine · magainin 2 · melittin · membrane lipid · nisin · phosphatidylglycerol · protegrin · tachyplesin · unclassified drug · virulence factor · virulence factor mprf · animal model · antibiotic resistance · article · bacterial count · bactericidal activity · controlled study · Enterococcus faecalis · female · gene inactivation · mouse · Mycobacterium tuberculosis · neutrophil · nonhuman · nucleotide sequence · pathogenicity · priority journal · Pseudomonas aeruginosa · Staphylococcus aureus · surface charge · alpha-Defensins · Amino Acid Sequence · Animals · Anti-Bacterial Agents · Bacterial Proteins · Base Sequence · Cell Membrane · Defensins · DNA, Bacterial · Drug Resistance, Microbial · Esterification · Genes, Bacterial · Humans · Lysine · Molecular Sequence Data · Neutrophils · Peptides · Phosphatidylglycerols · Staphylococcus aureus · Swine · Virulence
[Abstract]

17 Direct cell-to-cell contact between Kupffer cells and hepatocytes augments endotoxin-induced hepatic injury
article 2001    
Author: Hoebe, K.H.N. · Witkamp, R.F. · Fink-Gremmels, J. · Miert, A.S.J.P.A.M. van · Monshouwer, M.
Keywords: Nutrition · Animals · Biotransformation · Blotting, Western · Cell Communication · Cell Membrane Permeability · Cell Survival · Cells, Cultured · Coculture Techniques · Endotoxins · Hepatitis, Toxic · Hepatocytes · Immunohistochemistry · Interleukin-6 · Kupffer Cells · Male · Nitric Oxide · Nitric Oxide Synthase · Nitric Oxide Synthase Type II · Reactive Oxygen Species · Swine · Tumor Necrosis Factor-alpha
[Abstract]

18 Stereoselectivity at the B2-adrenoceptor on macrophages is a major determinant of the anti-inflammatory effects of B2-agonists
article 2000    
Author: Izeboud, C.A. · Vermeulen, R.M. · Zwart, A. · Vos, H.P. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: β-Adrenoceptor · Stereoselectivity · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · 4 (3 tert butylamino 2 hydroxypropoxy) 2 benzimidazolone · Aprotinin · Benzylsulfonyl fluoride · Beta 2 adrenergic receptor · Beta 2 adrenergic receptor blocking agent · Beta 2 adrenergic receptor stimulating agent · Carmoterol · cyclic AMP · Interleukin 10 · Lipopolysaccharide · Tumor necrosis factor alpha · Xamoterol · Beta adrenergic receptor stimulating agent · Nonsteroid antiinflammatory agent · Antiinflammatory activity · Stereochemistry · Cell culture · Cell membrane · Drug antagonism · Metabolism · Radioassay · Signal transduction · Stereoisomerism · Adrenergic beta-Agonists · Anti-Inflammatory Agents, Non-Steroidal · Cell Membrane · Cells, Cultured · Cyclic AMP · Humans · Interleukin-10 · Lipopolysaccharides · Macrophages · Radioligand Assay · Receptors, Adrenergic, beta-2 · Signal Transduction · Stereoisomerism · Tumor Necrosis Factor-alpha
[Abstract]

19 Automated electron tomography of the septal pore cap in Rhizoctonia solani
article 2000    
Author: Müller, W.H. · Koster, A.J. · Humbel, B.M. · Ziese, U. · Verkleij, A.J. · Aelst, A.C. van · Krift, T.P. van der · Montijn, R.C. · Boekhout, T.
Keywords: Nutrition · Botany · Fungi · β-1,6-glucan · Cryo-scanning electron microscopy · Dolipore septum · Electron tomography · Filamentous structures · Freeze substitution · Fungus · High-pressure freezing · Rhizoctonia solani · Septal pore cap · Transmission electron microscopy · ZIO staining · Automation · Cell communication · Cell ultrastructure · Channel gating · Diagnostic value · Electron beam tomography · Hyphomycetes · Membrane structure · Nonhuman · Priority journal · Automation · Cell Membrane · Cryoelectron Microscopy · Electrons · Endoplasmic Reticulum · Freezing · Image Processing, Computer-Assisted · Intercellular Junctions · Intracellular Membranes · Microscopy, Electron · Microscopy, Electron, Scanning · Mitochondria · Rhizoctonia · Tomography · Basidiomycota · Fungi · Hyphomycetes · Rhizoctonia · Thanatephorus cucumeris
[Abstract]

20 Expression of cbsA encoding the collagen-binding S-protein of Lactobacillus crispatus JCM5810 in Lactobacillus casei ATCC 393T
article 2000    
Author: Martínez, B. · Sillanpää, J. · Smit, E. · Korhonen, T.K. · Pouwels, P.H.
Keywords: Nutrition · Bacterial protein · Binding protein · Collagen binding s protein · Unclassified drug · Bacterium adherence · Gene expression · Lactobacillus · Lactobacillus casei · Lactobacillus crispatus · Nonhuman · Priority journal · Protein secretion · Signal transduction · Bacterial Proteins · Cell Membrane · Integrins · Lactobacillus · Lactobacillus casei · Membrane Glycoproteins · Membrane Proteins · Receptors, Collagen · Bacteria (microorganisms) · Lactobacillus casei · Lactobacillus crispatus · Posibacteria
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 39 found. Next | Sort by relevance