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The mutagenicity of isoniazid in salmonella and its effects on DNA repair and synthesis in human fibroblasts

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Author: Wade, D.R. · Lohman, P.H.M.
Type:article
Date:1980
Institution: Medisch Biologisch Laboratorium TNO
Source:Mutation Research, 3, 74, 71
Identifier: 228901
Keywords: Biology · Hydrazine · Isoniazid · Manganese · Abstract report · Adverse drug reaction · Cell culture · Chemical mutagenesis · DNA repair · DNA synthesis · Fibroblast · Human · Human cell · In vitro study · Liver microsome · Mouse · Mutagenicity · Normal human · Pharmacokinetics · Rat · Salmonella · Salmonella typhimurium · Soft tissue

Abstract

Chemicals/CAS: hydrazine, 10217-52-4, 13775-80-9, 18500-32-8, 302-01-2, 7803-57-8; isoniazid, 54-85-3, 62229-51-0, 65979-32-0; manganese, 16397-91-4, 7439-96-5