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Hypertension and road traffic noise exposure

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Author: Kluizenaar, Y. de · Gansevoort, R.T. · Miedema, H.M.E. · Jong, P.E. de
Institution: TNO Bouw en Ondergrond
Source:Journal of Occupational and Environmental Medicine, 5, 49, 484-492
Identifier: 239963
doi: doi:10.1097/JOM.0b013e318058a9ff
Keywords: Health Traffic · antihypertensive agent · adult · aged · antihypertensive therapy · article · cohort analysis · controlled study · cross-sectional study · diastolic blood pressure · disease association · environmental exposure · female · human · hypertension · major clinical study · male · prevalence · prevention study · random sample · risk assessment · self report · systolic blood pressure · traffic noise · Adult · Aged · Automobiles · Cohort Studies · Environmental Monitoring · Female · Humans · Hypertension · Male · Middle Aged · Netherlands · Noise, Transportation · Odds Ratio · Questionnaires


OBJECTIVE: The purpose of this study was to assess the relationship between road traffic noise exposure at home and the prevalence of hypertension. METHODS: We conducted cross-sectional analyses in a large random sample (N = 40,856) of inhabitants of Groningen City, and in a subsample (the Prevention of Renal and Vascular End-Stage Disease [PREVEND]) study cohort; N = 8592). RESULTS: Before adjustment for confounders, road traffic noise exposure was associated with self-reported use of antihypertensive medication in the city of Groningen sample (odds ratio [OR] = 1.31 per 10-dB increase in Lden). Adjusted odds ratios were significant for the subjects between 45 and 55 years old in the full model when adjusted for PM10 (OR = 1.19) and at higher exposure (Lden >55 dB) only (OR = 1.21; with adjustment for PM10, OR = 1.31). In the PREVEND cohort, the unadjusted odds ratio was 1.35 for hypertension (systolic and diastolic blood pressure >140 and >90 mm Hg, respectively, or use of antihypertensive medication). Again, the adjusted odds ratio was significant for subjects between 45 and 55 years old (OR = 1.27; with adjustment for PM10, OR = 1.39). CONCLUSIONS: Exposure to road traffic noise may be associated with hypertension in subjects who are between 45 and 55 years old. Associations seemed to be stronger at higher noise levels. ©2007The American College of Occupational and Environmental Medicine.