The study From Farm to Fork and Further shows how, as traditional causes of food safety problems such as basic hygiene are successfully dealt with, future food safety risks become ever harder to manage. European countries may have the highest food safety standards, however the trends that go hand in hand with rising wealth also lead to new risks, which emerge principally due to three trends: changing consumptions patterns; increasing complexity of food chains; and rapid developments in food innovation. As a result, new food safety risks arise, especially in relation to zoonotic diseases, antibiotic resistance, chemical hazards and allergies. If we do not address these risks, they are likely to evolve into the food safety crises of tomorrow. Our report suggests several areas for R&D to help us face these challenges.