Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Influence of retinoids on the mutagenicity of cigarette-smoke condensate in Salmonella typhimurium TA98

Publication files not online:

Author: Wilmer, J.W.G.M. · Spit, B.J.
Type:article
Date:1986
Institution: Instituut CIVO-Toxicologie en voeding TNO
Source:Mutation Research, 1, 173, 9-11
Identifier: 230059
Keywords: Cigarette smoke condensate · Retinoic acid · Retinol · Retinol acetate · Tobacco · Ames test · Chemical mutagenesis · Heredity · In vitro study · Mutagenicity · Nonhuman · Priority journal · Salmonella typhimurium · Comparative Study · Mutagenicity Tests · Mutagens · Mutation · Retinoids · Salmonella typhimurium · Smoke · Smoking · Structure-Activity Relationship · Support, Non-U.S. Gov't

Abstract

The effects of 3 different retinoids (all-trans-retinol, all-trans-retinoic acid, and all-trans-retinyl acetate) on the mutagenic activity of cigarette-smoke condensate were investigated in Salmonella typhimurium TA98. Neither an enhancing nor an inhibitory effect of the retinoids on the mutagenicity of cigarette-smoke condensate was observed. Chemicals/CAS: retinoic acid, 302-79-4; retinol acetate, 127-47-9; retinol, 68-26-8, 82445-97-4; Mutagens; Retinoids