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Moderate drinking : No impact on female fecundity

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Author: Zaadstra, B.M. · Looman, C.W.N. · Velde, E.R. te · Habbema, J.D.F. · Karbaat, J.
Institution: Nederlands Instituut voor Praeventieve Gezondheidszorg TNO
Source:Fertility and Sterility, 5, 62, 948-954
Identifier: 232418
Keywords: Health · Alcohol · Fecundity · Alcohol consumption · Artificial insemination · Clinical trial · Conception · Embryo development · Female fertility · Lifestyle · Major clinical study · Adult · Alcohol Drinking · Coffee · Female · Fertility · Human · Insemination, Artificial, Heterologous · Pregnancy · Prospective Studies · Smoking


Objective: To determine the effect of moderate alcohol intake on probability of conception. Design: Prospective cohort study. Setting: Normal healthy women enrolled in an artificial donor insemination program. Patients: Women starting artificial donor insemination for the very first time were selected. Interventions: Alcohol exposure was measured through a self- administered questionnaire at intake of study. Main Outcome Measure: A first positive pregnancy test as indicative for conception. Results: Women with moderate alcohol intake had a slightly higher, though not significant, probability of conception compared with nondrinkers (Hazard Ratio 1.20; 95% confidence interval 0.90 to 1.60). Conclusion: Moderate alcohol intake has no negative impact on female fecundity.