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Criteria for a specific plasmin inhibition test (SPIT) in human plasma

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Author: Meijer, P. · Kluft, C.
Institution: Gaubius Laboratory TNO Preventie en Gezondheid
Source:Fibrinolysis, SUPPL. 2, 10, 121-123
Identifier: 233519
Keywords: Biology · alpha 2 antiplasmin · plasmin · assay · blood level · conference paper · controlled study · fibrinolysis · human · priority journal


Test procedures of several commercially available functional test kits for α2-antiplasmin were investigated. The importance of the plasmin concentration, the amount of plasma used in the test and the preincubation time for a specific test for the determination of α2-antiplasmin were discussed. A Specific Plasmin Inhibition Test (SPIT) suitable for automation was developed.