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Isocyanate exposure and respiratory symptoms in Dutch car spray painters

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Author: Heederik, D. · Pronk, A. · Doekes, G. · Bobbeldijk, I. · Preller, L.
Institution: TNO Kwaliteit van Leven
Source:Zentralblatt fur Arbeitsmedizin, Arbeitsschutz und Ergonomie, 1, 55, 20-22
Identifier: 238369
Keywords: Chemistry Safety · Analytical research · Isocyanate · Respiratory disease · Spray painters · hexamethylene diisocyanate · isocyanate · monomer · oligomer · article · car · health survey · human · industrialization · Netherlands · occupational allergy · occupational asthma · occupational exposure · occupational lung disease · painter · prevalence


Isocyanate allergy and asthma is an important respiratory disease in most industrialized countries. Little information about its importance is available for the Netherlands. A baseline survey, part of a larger longitudinal epidemiological survey, shows that exposure to mainly HDI monomers and oligomers is present. The respiratory symptoms prevalence, especially of work related symptoms, is high and sensitization to isocyanates was observed in some cases. A more detailed evaluation is required to get insight in the magnitude of isocyanate exposure related respiratory disease.