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Oxygen-tension measurements - The first step towards prevention and early detection of anastomotic leakage

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Author: Tanase, D. · French, P.J. · Komen, N. · Kleinrensink, G.J. · Jeekel, J. · Lange, J.F. · Draaijer, A.
Type:article
Date:2007
Institution: TNO Kwaliteit van Leven
Source:6th IEEE Conference on SENSORS, IEEE SENSORS 2007, 28 October 2007 through 31 October 2007, Atlanta, GA, Conference code: 72850, 68-71
series:
Proceedings of IEEE Sensors
Identifier: 240438
doi: doi:10.1109/ICSENS.2007.4388337
Article number: No.: 4388337
Keywords: Analytical research · Carbon dioxide · Leakage (fluid) · Oxygen · Oxygenation · Surgery · Temperature sensors · Early detections · In-vivo · Measurement systems · Rat kidneys · Recovery periods · Reperfusion · Sensor chips · Sensor systems · Tension measurements · Tissue oxygenations · Sensors

Abstract

Many patients still die every year as a result of anastomotic leakage after surgery. The medical world needs an objective aid to detect leakage during surgery and during the critical recovery period. We propose a miniature measurement system to detect adequate tissue oxygenation pre- and postoperatively (continuously for 7 days) on the colon. The sensor chip should include an oxygen-saturation sensor, an oxygen-tension sensor, a carbon dioxide tension sensor and a temperature sensor. The work presented here focuses on the measurements done with the oxygen-tension and temperature sensors. In-vitro measurements were carried out to test the sensor system and initial in-vivo tests were performed on a rat kidney, during an ischemia-reperfusion experiment. ©2007 IEEE.