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Development of immune organs and functioning in humans and testanimals: Implications for immune intervention studies

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Author: Kuper, C.F. · Bilsen, J. van · Cnossen, H. · Houben, G. · Garthoff, J. · Wolterbeek, A.
Source:Reproductive Toxicology, 64, 180–190
Identifier: 572677
Keywords: Nutrition · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences


Ahealthyimmunestatus is mostly determined during early life stages andmanyimmune-related diseases may find their origin in utero and the first years of life. Therefore, immune health optimization may be most effective during early life. This review is an inventory of immune organ maturation events in relation