The increasing complexity of embedded systems requires performance evaluation early in the design phase. We introduce a generic way of generating performance models based on a system description given in a domain-specific language (DSL). We provide a transformation from a DSL to a performance model in the Parallel Object-Oriented Specification Language (POOSL). A case study shows the feasibility of the approach in a complex interventional X-ray system, which requires appropriate measurement data on a prototype. Since distance computations are an integral part of the system, performance profiles of our chosen distance package, Proximity Query Package, have been created. The overall model has been successfully validated by comparing its outcomes with real measurements. © 2013 Springer-Verlag Berlin Heidelberg.