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Dose-response relation between physical activity and sick leave

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Author: Proper, K.I. · Heuvel, S.G. van den · Vroome, E.M. de · Hildebrandt, V.H. · Beek, A.J. van der
Institution: TNO Kwaliteit van Leven
Source:British Journal of Sports Medicine, 2, 40, 173-178
Identifier: 239118
doi: doi:10.1136/bjsm.2005.022327
Keywords: Workplace · Veilig en Gezond Werken · Analysis of variance · Controlled study · Dose response · Linear regression analysis · Logistic regression analysis · Major clinical study · Medical leave · Netherlands · outcome assessment · physical activity · Adult · Cohort Studies · Cross-Sectional Studies · Exercise · Female · Health Status · Humans · Male · Middle Aged · Netherlands · Prospective Studies · Regression Analysis · Sick Leave


Objective: To investigate the dose-response relation between moderate and vigorous physical activity and sick leave in a working population. Methods: Data were used from three large Dutch databases: two continuous, cross sectional surveys among a representative sample of the Dutch population and one prospective cohort study. A distinction was made between duration, frequency and intensity of physical activity. The outcome measure was the number of days of sick leave. Analyses of variance were used to compare sick leave (in days) for workers with different amounts of physical activity, in particular workers meeting the physical activity recommendations v those who did not. Linear and logistic regression analyses were used to obtain effect estimates in the prospective cohort study, with the generalised estimating equation (GEE) method. Results: No relation was round between moderate physical activity and sick leave. In two databases, workers meeting the recommendation of vigorous physical activity (active at a vigorous level for at least three times a week) had significantly less sick leave: more than one day over two months and more than four days over a year. The duration of vigorous physical activity was not associated with sick leave. Conclusion: Physical activity at a vigorous intensity level for at least three times a week, as in the CDC/ACSM recommendation, has a positive effect on sick leave.