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Sex steroids and lipoprotein metabolism

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Author: Gevers Leuven, J.A.
Type:article
Date:1994
Institution: Gaubius Laboratory TNO Preventie en Gezondheid
Source:Pharmacology and Therapeutics, 1, 64, 99-126
Identifier: 232699
doi: doi:/10.1016/0163-7258(94)90035-3
Keywords: Health · Cardiovascular risk · Cholesterol · Estrogens · Lipoproteins · Progestogens · Sex steroids · chlormadinone acetate · cholesterol · conjugated estrogen · cyproterone acetate · desogestrel · dydrogesterone · gestodene · high density lipoprotein · hydroxytamoxifen · low density lipoprotein · lynestrenol · medrogestone · medroxyprogesterone acetate · mifepristone · norethisterone · noretynodrel · norgestimate · norgestrel · oral contraceptive agent · sex hormone · steroid receptor · very low density lipoprotein · atherogenesis · cardiovascular disease · drug structure · lipid metabolism · lipoprotein metabolism · Animal · Arteriosclerosis · Cardiovascular Diseases · Contraceptives, Oral, Hormonal · Female · Human · Lipoproteins · Male · Risk Factors · Sex Hormones

Abstract

Lipoprotein metabolism is involved in atherogenesis. Female sex-hormones have substantial effects on both lipoprotein metabolism and the vessel wall. Cholesterol, one of the major lipids in lipoproteins, is both the substrate for, and the target of, the steroidal sex hormones.