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Absence of a correlation between humoral and cellular responses to vaccinia virus and products of the major histocompatibility complex in rhesus monkeys

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Author: Stitz, L. · Kreeftenberg, J.G. · Loggen, H.G. · Balner, H.
Institution: Primatencentrum TNO
Source:Antiviral Research, 3, 1, 193-199
Identifier: 229087
doi: doi:10.1016/0166-3542(81)90008-5
Keywords: radioisotope · animal experiment · antibody production · blood and hemopoietic system · blood group rhesus system · heredity · immune response · lymphocyte proliferation · lymphocyte transformation · major histocompatibility complex · monkey · thymidine h 3 · Animal · Antibodies, Viral · Female · Histocompatibility Antigens · Lymphocyte Activation · Macaca mulatta · Male · Vaccinia · Vaccinia virus


62 Rhesus monkeys were tested at different times after vaccinia virus infection for virus-specific induction of lymphocyte proliferation in vitro or antibody production in vivo. No association was found between identifiable RhLA-controlled antigens and the strength of the cellular proliferative and/or humoral response. Chemicals/CAS: Antibodies, Viral; Histocompatibility Antigens