Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Alcohol consumption and risk of type 2 diabetes among older women

Publication files not online:

Author: Beulens, J.W.J. · Stolk, R.P. · Schouw, Y.T. van der · Grobbee, D.E. · Hendriks, H.F.J. · Bots, M.L.
Type:article
Date:2005
Institution: TNO Kwaliteit van Leven
Source:Diabetes Care, 12, 28, 2933-2938
Identifier: 238881
doi: doi:10.2337/diacare.28.12.2933
Keywords: Health · Biomedical Research · adult · aged · alcohol consumption · article · beverage · blood sampling · controlled study · disease association · female · follow up · hazard assessment · human · major clinical study · non insulin dependent diabetes mellitus · prospective study · questionnaire · beer · blood pressure · body mass · body size · clinical trial · drinking behavior · middle aged · multicenter study · Netherlands · risk assessment · smoking · wine · Aged · Alcohol Drinking · Beer · Blood Pressure · Body Mass Index · Body Size · Diabetes Mellitus, Type 2 · Female · Humans · Middle Aged · Netherlands · Questionnaires · Risk Assessment · Smoking · Wine

Abstract

OBJECTIVE - This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women. RESEARCH DESIGN AND METHODS - Between 1993 and 1997, 16,330 women aged 49-70 years and free from diabetes were enrolled in one of the Dutch Prospect-EPIC (European Prospective Study Into Cancer and Nutrition) cohorts and followed for 6.2 years (range 0.1-10.1). At enrollment, women filled in questionnaires and blood samples were collected. RESULTS - During follow-up, 760 cases of type 2 diabetes were documented. A linear inverse association (P = 0.007) between alcohol consumption and type 2 diabetes risk was observed, adjusting for potential confounders. Compared with abstainers, the hazard ratio for type 2 diabetes was 0.86 (95% CI 0.66-1.12) for women consuming 5-30 g alcohol per week, 0.66 (0.48-0.91) for 30-70 g per week, 0.91 (0.67-1.24) for 70-140 g per week, 0.64 (0.44-0.93) for 140-210 g per week, and 0.69 (0.47-1.02) for >210 g alcohol per week. Beverage type did not influence this association. Lifetime alcohol consumption was associated with type 2 diabetes in a U-shaped fashion. CONCLUSIONS - Our findings support the evidence of a decreased risk of type 2 diabetes with moderate alcohol consumption and expand this to a population of older women. © 2005 by the American Diabetes Association.