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Histopathology of mucosa-associated lymphoid tissue

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Author: Kuper, C.F.
Institution: TNO Kwaliteit van Leven
Source:Toxicologic Pathology, 5, 34, 609-615
Identifier: 239416
doi: doi:10.1080/01926230600867735
Keywords: Biology · Toxicology and Applied Pharmacology · Granulomas · Lymphatic ectasia · Macrophage aggregates · MALT lymphoma · bronchus · conference paper · histopathology · human · inflammation · intestine lymphatic tissue · lymphoid tissue · metastasis · mucosa associated lymphoid tissue lymphoma · nasopharynx · neoplasm · nonhuman · Peyer patch · priority journal · Animals · Granuloma · Inflammation · Lymphoid Tissue · Lymphoma, Mucosa-Associated Lymphoid Tissue · Mice · Mucous Membrane · Rats


Mucosa-associated lymphoid tissue (MALT) is a generalized term incorporating a disseminated collection of lymphoid tissues in multiple sites throughout the body. MALT sites that have been/are primarily studied include bronchus-associated lymphoid tissue (BALT), gut-associated lymphoid tissue (GALT), and nasopharynx-associated lymphoid tissue (NALT). Since MALT sites are often under-sampled in conventional toxicity studies, MALT lesions have not been extensively documented in these lymphoid effector sites. Lesions of the nasopharyngeal lymphoid tissue and Peyer's patches include degeneration, inflammation, and both primary and metastatic neoplasia. Copyright © by the Society of Toxicologic Pathology.