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In Vitro demonstration of an SpO2-Camera

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Author: Wieringa, F.P. · Mastik, F. · Boks, R.H. · Visscher, A. · Bogers, A. · Steen, A.F.W. van der
Type:article
Date:2007
Institution: TNO Industrie en Techniek
Source:Computers in Cardiology 2007, CAR 2007, 30 September - 3 October 2007, Durham, NC, USA, 34, 749-751
Identifier: 240500
Article number: No.: 4745594
Keywords: Electronics · Blood oxygenations · Human blood · In-vitro · Oxygen saturation levels · Pulse oximeters · Reproducibility · Blood gas analysis · Cameras · Cardiology · Electronic medical equipment · Laboratories · Industrial Innovation

Abstract

Feasibility of pulse oxigraphy is examined using an in- vitro phantom, perfused with human blood by a heart- lung machine. 29 different oxygen saturation levels, measured with our experimental camera and a clinical pulse oximeter, were matched against laboratory blood gas analysis. Discrete transfer functions between measurements & laboratory values were derived for camera (fCAM-LAB) & pulse oximeter fPulse-lab). 87 additional independent pulse oximeter & camera measurements were subjected to these functions to check reproducibility (R2 = 0.99). To demonstrate imaging capacities, a dual reservoir was applied to image venous and arterial samples from 2 patients. Camera-derived vs laboratory arterial values were: 97.0% vs 99.5% (pat. 1, pH=7.41) & 97.5% vs 99.5% (pat. 2, pH=7.37). Venous resulst were: 86.5% vs 74.4% (pat. 1, pH=7.39) & 89.1% vs 86.2% (pat. 2, pH=7.34). In vitro pulse oxigraphy can visualize regions with different blood oxygenation.