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Nutritional effects of alkali treated soyprotein in rats

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Author: Beek, L. van · Feron, V.J. · Groot, A.P. de
Type:article
Date:1974
Institution: Centraal Instituut voor Voedingsonderzoek TNO
Source:Journal of Nutrition, 12, 104, 1630-1636
Identifier: 227769
Keywords: ketone body · protein · alanine aminotransferase blood level · alkaline phosphatase blood level · aspartate aminotransferase blood level · body weight · dose response · drug response · erythrocyte count · feeding behavior · glucosuria · growth · histology · kidney · kidney calcification · leukocyte count · microscopy · oral drug administration · organ · proteinuria · rat · sex · sex difference · soybean · theoretical study · urine · urine ph · Alanine Transaminase · Alkaline Phosphatase · Animal · Animal Nutrition · Aspartate Aminotransferases · Body Weight · Comparative Study · Dietary Proteins · Female · Hydrogen-Ion Concentration · Kidney · Male · Nephrocalcinosis · Organ Weight · Phosphorus · Rats · Sex Factors · Soybeans · Vegetable Proteins · production · technology · food · Medicine · Geneeskunde · Health · Gezondheid · Dietetics · Voedingsleer

Abstract

Alkali treated spun soy isolate was fed to rats at dietary levels of 5, 10, and 20% for a period of 90 days. The results failed to reveal any adverse effects on general appearance, growth, feeding efficiency, hematological indices, blood serum values, urine composition, kidney function, organ weights, and gross and microscopic pathology except for an increase in both the relative kidney weights and degree of nephrocalcinosis in females only. These renal changes were, however, shown to be related to the high dietary level of available phosphorus. Renal cytomegalia was not observed. Chemicals/CAS: protein, 67254-75-5; Alanine Transaminase, EC 2.6.1.2; Alkaline Phosphatase, EC 3.1.3.1; Aspartate Aminotransferases, EC 2.6.1.1; Dietary Proteins; Phosphorus, 7723-14-0; Vegetable Proteins