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Inactivation of high and low molecular weight single-chain urokinase-type plasminogen activator (pro-urokinase) by thrombin in the presence of thrombomodulin

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Author: Munk, G.A.W. de · Molinari, A. · Rijken, D.C.
Type:article
Date:1993
Institution: Gaubius Laboratory Netherlands Instituut voor verouderings- en vaatziekten onderzoek TNO
Source:Thrombosis and Haemostasis, 1, 69, 88
Identifier: 232133
Keywords: Health · amino acid · prourokinase · thrombomodulin · amino terminal sequence · comparative study · drug inactivation · letter · molecular weight · protein domain · protein structure · Enzyme Precursors · Molecular Weight · Receptors, Cell Surface · Receptors, Thrombin · Support, Non-U.S. Gov't · Thrombin · Urinary Plasminogen Activator

Abstract

Chemicals/CAS: amino acid, 65072-01-7; prourokinase, 82657-92-9; thrombin, 9002-04-4; thrombomodulin, 112049-68-0; Enzyme Precursors; Receptors, Cell Surface; Receptors, Thrombin; saruplase, 99149-95-8; Thrombin, EC 3.4.21.5; Urinary Plasminogen Activator, EC 3.4.21.73