Print Email Facebook Twitter Collective dynamics and pattern formation in systems of communicating cells Title Collective dynamics and pattern formation in systems of communicating cells: Theory and Simulations Author Dang, Y. (TU Delft OLD BN/Hyun Youk Lab) Contributor Dogterom, A.M. (promotor) Youk, H.O. (copromotor) Degree granting institution Delft University of Technology Date 2020-08-27 Abstract How a system of genetically identical biological cells organizes into spatially heterogeneous tissues is a central question in biology. Even when the molecular and genetic underpinnings of cell-cell interactions are known, how these lead to multicellular patterns is often poorly understood. Of particular interest are dynamic patterns such as traveling waves, which confer spatiotemporal control over key developmental processes such as differentiation, segmentation and cell division. Theoretical approaches based on mathematical descriptions of underlying physical and chemical processes provide a promising avenue to explore biological pattern formation. In particular, theoretical models connect processes on the molecular scale to biological function on the tissue level and may provide mechanistic descriptions of how patterns are generated and maintained. Subject pattern formationmulticellular systemscell-cell communicationself-organizationcomplex systemscellular automatagene networks To reference this document use: https://doi.org/10.4233/uuid:2b5f24d3-48ec-49a8-a20a-b6fd13a84dc9 ISBN 978-90-8593-435-6 Bibliographical note Casimir PhD Series, Delft-Leiden 2020-08 Part of collection Institutional Repository Document type doctoral thesis Rights © 2020 Y. Dang Files PDF Thesis_Yiteng_Dang.pdf 122.07 MB Close viewer /islandora/object/uuid:2b5f24d3-48ec-49a8-a20a-b6fd13a84dc9/datastream/OBJ/view