Print Email Facebook Twitter A patient-specific visualization tool for comprehensive analysis of coronary CTA and perfusion MRI data Title A patient-specific visualization tool for comprehensive analysis of coronary CTA and perfusion MRI data Author Kirisli, H.A. Gupta, V. Kirschbaum, S. Neefjes, L. Van Geuns, R.J. Mollet, N. Lelieveldt, B.P.F. Reiber, J.H.C. Van Walsum, T. Niessen, W.J. Faculty Electrical Engineering, Mathematics and Computer Science Department Intelligent Systems Date 2011-03-01 Abstract Cardiac magnetic resonance perfusion imaging (CMR) and computed tomography angiography (CTA) are widely used to assess heart disease. CMR is used to measure the global and regional myocardial function and to evaluate the presence of ischemia; CTA is used for diagnosing coronary artery disease, such as coronary stenoses. Nowadays, the hemodynamic significance of coronary artery stenoses is determined subjectively by combining information on myocardial function with assumptions on coronary artery territories. As the anatomy of coronary arteries varies greatly between individuals, we developed a patient-specific tool for relating CTA and perfusion CMR data. The anatomical and functional information extracted from CTA and CMR data are combined into a single frame of reference. Our graphical user interface provides various options for visualization. In addition to the standard perfusion Bull’s Eye Plot (BEP), it is possible to overlay a 2D projection of the coronary tree on the BEP, to add a 3D coronary tree model and to add a 3D heart model. The perfusion BEP, the 3D-models and the CTA data are also interactively linked. Using the CMR and CTA data of 14 patients, our tool directly established a spatial correspondence between diseased coronary artery segments and myocardial regions with abnormal perfusion. The location of coronary stenoses and perfusion abnormalities were visualized jointly in 3D, thereby facilitating the study of the relationship between the anatomic causes of a blocked artery and the physiological effects on the myocardial perfusion. This tool is expected to improve diagnosis and therapy planning of early-stage coronary artery disease. Subject computed tomography angiography (CTA)cardiac magnetic resonance perfusion imaging (CMR)coronary Artery Disease (CAD)diagnosis, visualization. To reference this document use: http://resolver.tudelft.nl/uuid:8eb28228-889c-412f-b6e1-8e2f7976fcc5 DOI https://doi.org/10.1117/12.873050 Publisher SPIE ISSN 0277-386X Source https://doi.org/10.1117/12.873050 Source Proceedings of SPIE, 2011 vol. 7964 Part of collection Institutional Repository Document type conference paper Rights (c)2011 The Authors Files PDF 2011-7964.Kirisli.pdf 3.29 MB Close viewer /islandora/object/uuid:8eb28228-889c-412f-b6e1-8e2f7976fcc5/datastream/OBJ/view