Print Email Facebook Twitter Comparison of Phase-Screen and Geometry-Based Phase Aberration Correction Techniques for Real-Time Transcranial Ultrasound Imaging Title Comparison of Phase-Screen and Geometry-Based Phase Aberration Correction Techniques for Real-Time Transcranial Ultrasound Imaging Author Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging) Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC) de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC) Renaud, G.G.J. (TU Delft ImPhys/Medical Imaging) Date 2022 Abstract While transcranial ultrasound imaging is a promising diagnostic modality, it is still hindered due to phase aberration and multiple scattering caused by the skull. In this paper, we compare near-field phase-screen modeling (PS) to a geometry-based phase aberration correction technique (GB) when an ultrafast imaging sequence (five plane waves tilted from −15 to +15 degrees in the cutaneous tissue layer) is used for data acquisition. With simulation data, the aberration profile (AP) of two aberrator models (flat and realistic temporal bone) was estimated in five isoplanatic patches, while the wave-speed of the brain tissue surrounding the point targets was either modeled homogeneously (ideal) or slightly heterogeneously to generate speckle (for mimicking a more realistic brain tissue). For the experiment, a phased array P4-1 transducer was used to image a wire phantom; a 4.2-mm-thick bone-mimicking plate was placed in front of the probe. The AP of the plate was estimated in three isoplanatic patches. The numerical results indicate that, while all the scatterers are detectable in the image reconstructed by the GB method, many scatterers are not detected with the PS method when the dataset used for AP estimation is generated with a realistic bone model and heterogeneous brain tissue. The experimental results show that the GB method increases the signal-to-clutter ratio (SCR) by 7.5 dB and 6.5 dB compared to the PS and conventional reconstruction methods, respectively. The GB method reduces the axial/lateral localization error by 1.97/0.66 mm and 2.08/0.7 mm compared to the PS method and conventional reconstruction, respectively. The lateral spatial resolution (full-width-half-maximum) is also improved by 0.1 mm and 1.06 mm compared to the PS method and conventional reconstruction, respectively. Our comparison study suggests that GB aberration correction outperforms the PS method when an ultrafast multi-angle plane wave sequence is used for transcranial imaging with a single transducer. Subject transcranial ultrasound imagingphase aberration correctionnear-field phase-screen modelingadaptive beamformingtemporal bone To reference this document use: http://resolver.tudelft.nl/uuid:fe622d93-9aed-4731-9240-50196c3781e3 DOI https://doi.org/10.3390/app121910183 ISSN 2076-3417 Source Applied Sciences, 12 (19) Part of collection Institutional Repository Document type journal article Rights © 2022 M. Mozaffarzadeh, M.D. Verweij, N. de Jong, G.G.J. Renaud Files PDF applsci_12_10183.pdf 1.61 MB Close viewer /islandora/object/uuid:fe622d93-9aed-4731-9240-50196c3781e3/datastream/OBJ/view