Title
Cardiovascular Magnetic Resonance for Patients With COVID-19
Author
Petersen, Steffen E. (Queen Mary University of London; Barts Health National Health Service Trust, London)
Friedrich, Matthias G. (McGill University)
Leiner, Tim (University Medical Center Utrecht; Mayo Clinic)
Elias, Matthew D. (Children's Hospital of Philadelphia)
Ferreira, Vanessa M. (University of Oxford)
Fenski, Maximilian (Charité Universittsmedizin Berlin; Helios Klinikum Berlin Buch; Deutsches Zentrum für Herz-Kreislaufforschung-Partnersite-Berlin)
Flamm, Scott D. (Cleveland Clinic, Cleveland)
Fogel, Mark (University of Pennsylvania)
Tao, Q. (TU Delft ImPhys/Medical Imaging; Leiden University Medical Center)
Date
2022
Abstract
COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19–related myocarditis is likely infrequent, COVID-19–related cardiovascular histopathology findings have been reported in up to 48% of patients, raising the concern for long-term myocardial injury. Studies to date report CMR abnormalities in 26% to 60% of hospitalized patients who have recovered from COVID-19, including functional impairment, myocardial tissue abnormalities, late gadolinium enhancement, or pericardial abnormalities. In athletes post–COVID-19, CMR has detected myocarditis-like abnormalities. In children, multisystem inflammatory syndrome may occur 2 to 6 weeks after infection; associated myocarditis and coronary artery aneurysms are evaluable by CMR. At this time, our understanding of COVID-19–related cardiovascular involvement is incomplete, and multiple studies are planned to evaluate patients with COVID-19 using CMR. In this review, we summarize existing studies of CMR for patients with COVID-19 and present ongoing research. We also provide recommendations for clinical use of CMR for patients with acute symptoms or who are recovering from COVID-19.
Subject
cardiovascular magnetic resonance
COVID-19
ischemia
multisystem inflammatory syndrome
myocardial injury
myocarditis
SARS-CoV-2
To reference this document use:
http://resolver.tudelft.nl/uuid:89936d48-0c72-4bb3-9f2b-5b03bfc7cf9e
DOI
https://doi.org/10.1016/j.jcmg.2021.08.021
Embargo date
2023-07-01
ISSN
1936-878X
Source
JACC: Cardiovascular Imaging, 15 (4), 685-699
Bibliographical note
Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.
Part of collection
Institutional Repository
Document type
review
Rights
© 2022 Steffen E. Petersen, Matthias G. Friedrich, Tim Leiner, Matthew D. Elias, Vanessa M. Ferreira, Maximilian Fenski, Scott D. Flamm, Mark Fogel, Q. Tao, More Authors