Print Email Facebook Twitter Multispectral MRI centerline tracking in carotid arteries Title Multispectral MRI centerline tracking in carotid arteries Author Tang, H. Van Walsum, T. Van Onkelen, R.S. Klein, S. Hameeteman, R. Schaap, M. Van den Bouwhuijsen, Q. Witteman, J.C.M. Van der Lugt, A. Van Vliet, L.J. Niessen, W.J. Faculty Applied Sciences Department Image Science and Technology Date 2011-03-11 Abstract We propose a minimum cost path approach to track the centerlines of the internal and external carotid arteries in multispectral MR data. User interaction is limited to the annotation of three seed points. The cost image is based on both a measure of vessel medialness and lumen intensity similarity in two MRA image sequences: Black Blood MRA and Phase Contrast MRA. After intensity inhomogeneity correction and noise reduction, the two images are aligned using affine registration. The two parameters that control the contrast of the cost image were determined in an optimization experiment on 40 training datasets. Experiments on the training datasets also showed that a cost image composed of a combination of gradient-based medialness and lumen intensity similarity increases the tracking accuracy compared to using only one of the constituents. Furthermore, centerline tracking using both MRA sequences outperformed tracking using only one of these MRA images. An independent test set of 152 images from 38 patients served to validate the technique. The centerlines of 148 images were successfully extracted using the parameters optimized on the training sets. The average mean distance to the reference standard, manually annotated centerlines, was 0.98 mm, which is comparable to the in-plane resolution. This indicates that the proposed method has a high potential to replace the manual centerline annotation. Subject minimum cost path, medialness, lumen intensity similarity, multispectral MRA, carotid artery, centerlines To reference this document use: http://resolver.tudelft.nl/uuid:cc9ee004-9a79-46d6-bd53-3a95058c50f4 DOI https://doi.org/10.1117/12.877817 Publisher SPIE ISSN 0277-786X Source https://doi.org/10.1117/12.877817 Source Proceedings of SPIE, 2011 vol. 7962 Part of collection Institutional Repository Document type conference paper Rights (c)2011 The Authors Files PDF 2011-7962.Tang.pdf 897.46 KB Close viewer /islandora/object/uuid:cc9ee004-9a79-46d6-bd53-3a95058c50f4/datastream/OBJ/view