Zero discharge: the need for clean shipping in the future

Evaluating Contextual Processing in Diffusion MRI: Application to Optic Radiation Reconstruction for Epilepsy Surgery

Diffusion MRI and tractography allow for investigation of the architectural configuration of white matter in vivo, offering new avenues for applications like presurgical planning. Despite the promising outlook, there are many pitfalls that complicate its use for (clinical) application. Amongst these are inaccuracies in the geometry of the...

Multi-catalytic route for the synthesis of (S)-tembamide

Enantiopure β-amino alcohols constitute one of the most significant building blocks for the synthesis of active pharmaceutical ingredients. Despite the availability of a range of chiral β-amino alcohols from a chiral pool, there is a growing demand for new enantioselective synthetic routes to vicinal amino alcohols and their derivatives. In...

Bienzymatic cascade for the synthesis of an optically active O-benzoyl cyanohydrin

A concurrent bienzymatic cascade for the synthesis of optically pure (S)-4-methoxymandelonitrile benzoate ((S)-3) starting from 4-anisaldehyde (1) has been developed. The cascade involves an enantioselective Manihot esculenta hydroxynitrile lyase-catalyzed hydrocyanation of 1, and the subsequent benzoylation of the resulting cyanohydrin (S)-2...

Challenges and Opportunities for Academic Parents During COVID-19

Parents in academic careers face notable challenges that may go unrecognized by university management and/or policy makers. The COVID-19 pandemic has shed light on some of these challenges, as academic parents shifted to working from home while simultaneously caring for children. On the other hand, many parents found that the shift to working...

Many-Revolution Earth-Centred Solar-Sail Trajectory Optimisation Using Differential Dynamic Programming

This work demonstrates the usability of differential dynamic programming (DDP) to obtain optimal Earth-centred solar-sail trajectories. The dynamical model is implemented as a two-body problem, augmented with an ideal solar-sail reflectance model and accounts for eclipses. The numerical performance of the optimisation algorithm is enhanced by...

Design and construction of the ReciPlyDome, a lightweight modular reciprocal dome

In the event sector, where there is a search for architectural constructions with an innovative morphology, reuse is key to strive towards more sustainable events. Designing modular structures and detailing them for easy disassembly and re-assembly is an ideal way to encourage and facilitate reuse. This way a longer lifespan is assured for the...

Effectiveness of community-based mangrove management for coastal protection: A case study from Central Java, Indonesia

Management and restoration of mangrove forests to protect coasts are promoted in many countries, including Indonesia. Indonesian mangrove forests are actively restored and managed by local communities for their ecosystem services, including coastal protection. Whether community-based mangrove management (CBMM) is effective is still debated....