Mapping Contextual Factors Influencing Physical Activity Behavior of People with a Physical Demanding Job

People with a physically demanding job have an unhealthy disbalance in occupational and leisure-time physical activity (PA). We aimed to understand which contextual factors influence this disbalance, and explore opportunities for lifestyle interventions that could restore this disbalance. We applied a contextmapping study with six production...

Designing a lifestyle intervention for people with a physically demanding job

Cardiovascular diseases are a prevalent cause of death worldwide. People with physically demanding jobs tend to have poorer cardiovascular health than people with sedentary jobs. In contrast to leisure-time physical activity (PA), occupational PA (lifting, pushing, and pulling heavy loads over a long period without sufficient recovery) seems to...

Nuclear factor erythroid 2–related factor 2 (Nrf2) deficiency causes age-dependent progression of female osteoporosis

Background: Nuclear factor erythroid 2–related factor 2 (Nrf2) is a crucial transcription factor for cellular redox homeostasis. The association of Nrf2 with elderly female osteoporotic has yet to be fully described. The aim was to elucidate a potential age-dependent Nrf2 contribution to female osteoporosis in mice. Methods: Eighteen female...

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle underpowered complex datasets to provide new insights into the potential function of germline variants in breast cancer prognosis. This network-based analysis studies ~7.3 million variants in...

Tailoring supercurrent confinement in graphene bilayer weak links

The Josephson effect is one of the most studied macroscopic quantum phenomena in condensed matter physics and has been an essential part of the quantum technologies development over the last decades. It is already used in many applications such as magnetometry, metrology, quantum computing, detectors or electronic refrigeration. However,...

High-order optical aberration coefficients: Extension to finite objects and to telecentricity in object space

We extend the method for the automatic computation of high-order optical aberration coefficients to include (1) a finite object distance and (2) an infinite entrance pupil position (telecentricity in object space). We present coefficients of the power series expansion of the transverse aberration vector with respect to the normalized aperture...

An assessment of methodologies to evaluate flood losses and impacts

The objective of this Masters thesis report is to review and analyse the current published and unpublished knowledge on the methods to valuate the intangible losses associated with both environmental and social/health impacts of coastal and estuarial floods, including the techniques for Cost- Benefit-Analysis, Multi-Criteria-Analysis, and Life...

High efficiency, low pressure drop two-phase condenser: Final report

Capillary pumped two-phase systems are considered to be: -Prime candidates to provide efficient thermal management systems for future advanced spacecraft. -Promising candidates for the thermal control of advanced larger instruments (e.g. laser-based earth observation instruments) or microgravity experiments. In such capillary pumped two-phase...

Carrier Wave Signals Interfering with Loran-C