Hulsman, M. (author), Mentink, A. (author), Van Someren, E.P. (author), Dechering, K.J. (author), De Boer, J. (author), Reinders, M.J.T. (author) Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is a crucial step when comparing measurements from these arrays. Normalization is, however, far from a solved problem. Frequently, we encounter datasets with significant...
journal article 2010