Extracellular and intracellular effects of bioactive glass nanoparticles on osteogenic differentiation of bone marrow mesenchymal stem cells and bone regeneration in zebrafish osteoporosis model

Bioactive glass nanoparticles (BGNs) are well-recognized multifunctional biomaterials for bone tissue regeneration due to their capability to stimulate various cellular processes through released biologically active ions. Understanding the correlation between BGN composition and cellular responses is key to developing clinically usable BGN...

Synthesis, solubility and thermodynamic properties of N-A-S-H gels with various target Si/Al ratios

The synthesis of N-A-S-H gel with high Si/Al ratios (>2) has been rarely reported in the literature, leaving the establishment of a reliable synthesis route as an open challenge. This paper aims to synthesize N-A-S-H gels with Si/Al ratios ranging from 1 to 3 and establish their thermodynamic database. The effects of reaction temperature,...

Managing connected and automated vehicles with flexible routing at “lane-allocation-free” intersections

With the development of internet of vehicles and automated driving, individual-based trajectory control at intersections becomes possible. Trajectory planning and coordination for connected and automated vehicles (CAVs) have been studied at isolated “signal-free” intersections and in “signal-free” corridors under the fully CAV environment in...