The Effect of ECM Stiffness on Tip/Stalk Cell Patterning during Early Sprouting Angiogenesis: A computational approach

Angiogenesis, i.e. the formation of blood vessels from existing ones, plays a vital role in bone or wound healing. The expansion of vascularization facilitates the healing process through the delivery of oxygen and nutrients to the injured site and through the removal of waste products. Clinical observations indicate that impaired angiogenesis...