Mucoadhesive films inside the colonic tube: Performance in a three-dimensional world

A self-propelling colonoscopic device moving inside the colonic tube should be able to periodically grip safely to the colonic wall as well as to manipulate the generated friction. The feasibility of achieving high grip and friction manipulation by covering the device with mucoadhesive films is experimentally tested. More precisely, the...

Application of mucoadhesive in a colon inspection device

Colonic cancer is the second leading cause of death among cancers in the Western world. Early detection greatly improves the chances of survival. Colonoscopy is a non-invasive detection method through natural access, making it possible to look inside the colon, take biopsies and remove small polyps that can develop into cancer. Colonoscopy is...

The role of geometry in the friction generated on the colonic surface by mucoadhesive films

One of the main challenges in designing diagnostic devices able to move along the colon is their locomotion method. Generating friction without applying high normal forces is a key requirement in order to eliminate the risk of tissue damage. One possible solution is to generate friction by means of adhesive forces. For this reason, the device...