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Seidel, R. (author), Bloom, J.G.P. (author), Dekker, C. (author), Szczelkun, M.D. (author)The Type I restriction-modification enzyme EcoR124I is an archetypical helicase-based dsDNA translocase that moves unidirectionally along the 3'–5' strand of intact duplex DNA. Using a combination of ensemble and single-molecule measurements, we provide estimates of two physicochemical constants that are fundamental to a full description of...journal article 2008