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Comparison between dynamic gadoxetate-enhanced MRI and ^99m Tc-mebrofenin hepatobiliary scintigraphy with SPECT for quantitative assessment of liver function

Rassam, F. (author), Zhang, T. (author), Cieslak, K. P. (author), Lavini, C. (author), Stoker, J. (author), Bennink, R. J. (author), van Gulik, T. M. (author), van Vliet, L.J. (author), Runge, J. H. (author), Vos, F.M. (author)

Objectives: To compare Gd-EOB-DTPA dynamic hepatocyte-specific contrast-enhanced MRI (DHCE-MRI) with ^99m Tc-mebrofenin hepatobiliary scintigraphy (HBS) as quantitative liver function tests for the preoperative assessment of patients undergoing liver resection. Methods: Patients undergoing liver surgery and preoperative assessment...

journal article 2019

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Comparison of multi-tensor diffusion models' performance for white matter integrity estimation in chronic stroke

Filatova, O.G. (author), van Vliet, L.J. (author), Schouten, A.C. (author), Kwakkel, Gert (author), van der Helm, F.C.T. (author), Vos, F.M. (author)

Better insight into white matter (WM) alterations after stroke onset could help to understand the underlying recovery mechanisms and improve future interventions. MR diffusion imaging enables to assess such changes. Our goal was to investigate the relation of WM diffusion characteristics derived from diffusion models of increasing complexity...

journal article 2018

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A hybrid segmentation method for partitioning the liver based on 4D DCE-MR images

Zhang, T. (author), Wu, Z. (author), Runge, Jurgen H. (author), Lavini, Cristina (author), Stoker, Jaap (author), Van Gulik, Thomas (author), Cieslak, Kasia P. (author), van Vliet, L.J. (author), Vos, F.M. (author)

The Couinaud classification of hepatic anatomy partitions the liver into eight functionally independent segments. Detection and segmentation of the hepatic vein (HV), portal vein (PV) and inferior vena cava (IVC) plays an important role in the subsequent delineation of the liver segments. To facilitate pharmacokinetic modeling of the liver...

conference paper 2018

document

Ultrasound contrast agent imaging: Real-time imaging of the superharmonics

Peruzzini, D. (author), Viti, J. (author), Tortoli, P. (author), Verweij, M.D. (author), De Jong, N. (author), Vos, H.J. (author)

Currently, in medical ultrasound contrast agent (UCA) imaging the second harmonic scattering of the microbubbles is regularly used. This scattering is in competition with the signal that is caused by nonlinear wave propagation in tissue. It was reported that UCA imaging based on the third or higher harmonics, i.e. “superharmonic” imaging, shows...

conference paper 2015

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Growth-rate dependency of de novo resveratrol production in chemostat cultures of an engineered Saccharomyces cerevisiae strain

Vos, T. (author), De la Torre Cortes, P. (author), Van Gulik, W.M. (author), Pronk, J.T. (author), Daran-Lapujade, P.A.S. (author)

Introduction: Saccharomyces cerevisiae has become a popular host for production of non-native compounds. The metabolic pathways involved generally require a net input of energy. To maximize the ATP yield on sugar in S. cerevisiae, industrial cultivation is typically performed in aerobic, sugar-limited fed-batch reactors which, due to constraints...

journal article 2015

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Image registration based on the structure tensor of the local phase

Li, Z. (author), Van Vliet, L.J. (author), Stoker, J. (author), Vos, F.M. (author)

Image registration of medical images in the presence of large intra-image signal fluctuations is a challenging task. Our paper addresses this problem by introducing a new concept based on the structure tensor of the local phase. The local phase is calculated from the monogenic signal representation of the images. The local phase image is hardly...

conference paper 2015

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Calibrating Doppler imaging of preterm intracerebral circulation using a microvessel flow phantom

Camfferman, F.A. (author), Ecury-Goossen, G.M. (author), La Roche, J.E. (author), De Jong, N. (author), Van 't Leven, W. (author), Vos, H.J. (author), Verweij, M.D. (author), Nasserinejad, K. (author), Cools, F. (author), Govaert, P. (author), Dudink, J. (author)

Introduction: Preterm infants are born during critical stages of brain development, in which the adaptive capacity of the fetus to extra-uterine environment is limited. Inadequate brain perfusion has been directly linked to preterm brain damage. Advanced high-frequency ultrasound probes and processing algorithms allow visualization of...

journal article 2015

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One-step assembly and targeted integration of multigene constructs assisted by the I-SceI meganuclease in Saccharomyces cerevisiae

Kuijpers, N.G.A. (author), Chroumpi, S. (author), Vos, T. (author), Solis-Escalante, D. (author), Bosman, D. (author), Pronk, J.T. (author), Daran, J.G. (author), Daran-Lapujade, P.A.S. (author)

In vivo assembly of overlapping fragments by homologous recombination in Saccharomyces cerevisiae is a powerful method to engineer large DNA constructs. Whereas most in vivo assembly methods reported to date result in circular vectors, stable integrated constructs are often preferred for metabolic engineering as they are required for large-scale...

journal article 2013

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Improving alignment in Tract-based spatial statistics: Evaluation and optimization of image registration

De Groot, M. (author), Vernooij, M.W. (author), Klein, S. (author), Arfan Ikram, M. (author), Vos, F.M. (author), Smith, S.M. (author), Niessen, W.J. (author), Andersson, J.L.R. (author)

Anatomical alignment in neuroimaging studies is of such importance that considerable effort is put into improving the registration used to establish spatial correspondence. Tract-based spatial statistics (TBSS) is a popular method for comparing diffusion characteristics across subjects. TBSS establishes spatial correspondence using a combination...

journal article 2013

document

Top-down fabrication of plasmonic nanostructures for deterministic coupling to single quantum emitters

Pfaff, W. (author), Vos, A. (author), Hanson, R. (author)

Metal nanostructures can be used to harvest and guide the emission of single photon emitters on-chip via surface plasmon polaritons. In order to develop and characterize photonic devices based on emitter-plasmon hybrid structures, a deterministic and scalable fabrication method for such structures is desirable. Here, we demonstrate deterministic...

journal article 2013

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A computer-assisted model for detection of MRI signs of Crohn’s disease activity: Future or fiction?

Tielbeek, J.A.W. (author), Vos, F.M. (author), Stoker, J. (author)

Magnetic resonance imaging is increasingly used for abdominal evaluation and is more and more considered as the optimal imaging technique for detection of mural inflammation in patients with Crohn’s disease. Grading the disease activity is important in daily clinical practice to monitor the medical treatment and is assessed by evaluating...

journal article 2012

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How Molecular Competition Influences Fluxes in Gene Expression Networks

Vos, D. de (author), Bruggeman, F.J. (author), Westerhoff, H.V. (author), Bakker, B.M. (author)

Often, in living cells different molecular species compete for binding to the same molecular target. Typical examples are the competition of genes for the transcription machinery or the competition of mRNAs for the translation machinery. Here we show that such systems have specific regulatory features and how they can be analysed. We derive a...

journal article 2011

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Event-based progression detection strategies using scanning laser polarimetry images of the human retina

Vermeer, K.A. (author), Lo, B. (author), Zhou, Q. (author), Vos, F.M. (author), Vossepoel, A.M. (author), Lemij, H.G. (author)

Monitoring glaucoma patients and ensuring optimal treatment requires accurate and precise detection of progression. Many glaucomatous progression detection strategies may be formulated for Scanning Laser Polarimetry (SLP) data of the local nerve fiber thickness. In this paper, several strategies, all based on repeated GDx VCC SLP measurements,...

journal article 2011

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Estimation of Diffusion Properties in Crossing Fiber Bundles

Caan, M.W.A. (author), Ganesh Khedoe, H. (author), Poot, D.H.J. (author), Den Dekker, A.J. (author), Olabarriaga, S.D. (author), Grimbergen, K.A. (author), Van Vliet, L.J. (author), Vos, F.M. (author)

There is an ongoing debate on how to model diffusivity in fiber crossings. We propose an optimization framework for the selection of a dual tensor model and the set of diffusion weighting parameters b, such that both the diffusion shape and orientation parameters can be precisely as well as accurately estimated. For that, we have adopted the...

journal article 2010

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Detection and Segmentation of Colonic Polyps on Implicit Isosurfaces by Second Principal Curvature Flow

Van Wijk, C. (author), Van Ravesteijn, V.F. (author), Vos, F.M. (author), Van Vliet, L.J. (author)

Today’s computer aided detection systems for computed tomography colonography (CTC) enable automated detection and segmentation of colorectal polyps.We present a paradigm shift by proposing a method that measures the amount of protrudedness of a candidate object in a scale adaptive fashion. One of the main results is that the performance of the...

journal article 2010

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Automated Detection and Segmentation of Large Lesions in CT Colonography

Grigorescu, S.E. (author), Nevo, S.T. (author), Liedenbaum, M.H. (author), Truyen, R. (author), Stoker, J. (author), Van Vliet, L.J. (author), Vos, F.M. (author)

Computerized tomographic colonography is a minimally invasive technique for the detection of colorectal polyps and carcinoma. Computer-aided diagnosis (CAD) schemes are designed to help radiologists locating colorectal lesions in an efficient and accurate manner. Large lesions are often initially detected as multiple small objects, due to which...

journal article 2010

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Computer-Aided Detection of Polyps in CT Colonography Using Logistic Regression

Van Ravesteijn, V.F. (author), Van Wijk, C. (author), Vos, F.M. (author), Truyen, R. (author), Peters, J.F. (author), Stoker, J. (author), Van Vliet, L.J. (author)

We present a computer-aided detection (CAD) system for computed tomography colonography that orders the polyps according to clinical relevance. TheCADsystem consists of two steps: candidate detection and supervised classification. The characteristics of the detection step lead to specific choices for the classification system. The candidates are...

journal article 2010

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Constrained Registration of the Wrist Joint

Van de Giessen, M. (author), Streekstra, G.J. (author), Strackee, S.D. (author), Maas, M. (author), Grimbergen, K.A. (author), Van Vliet, L.J. (author), Vos, F.M. (author)

Comparing wrist shapes of different individuals requires alignment of these wrists into the same pose. Unconstrained registration of the carpal bones results in anatomically nonfeasible wrists. In this paper, we propose to constrain the registration using the shapes of adjacent bones, by keeping the width of the gap between adjacent bones...

journal article 2009

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Classifying CT Image Data Into Material Fractions by a Scale and Rotation Invariant Edge Model

Serlie, I.W. (author), Vos, F.M. (author), Truyen, R. (author), Post, F.H. (author), Van Vliet, L.J. (author)

A fully automated method is presented to classify 3-D CT data into material fractions. An analytical scale-invariant description relating the data value to derivatives around Gaussian blurred step edges—arch model—is applied to uniquely combine robustness to noise, global signal fluctuations, anisotropic scale, noncubic voxels, and ease of use...

journal article 2007

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Design of a modified GO-Finer

Honselaar, B. (author), Oehlers, V. (author), Vos, F. (author), Laurentius, S. (author)

report 2006