Single-cell transcriptomics links loss of human pancreatic β-cell identity to er stress

The maintenance of pancreatic islet architecture is crucial for proper β-cell function. We previously reported that disruption of human islet integrity could result in altered β-cell identity. Here we combine β-cell lineage tracing and single-cell transcriptomics to investigate the mechanisms underlying this process in primary human islet...

Roll-to-Roll Slot Die Coated Perovskite for Efficient Flexible Solar Cells

The feasibility of upscaling the perovskite solar cells technologies to high volume production using roll-to-roll (R2R) slot die coating is demonstrated in this study. Perovskite solar cells are produced by R2R slot die coating on flexible substrates with a width of 30 cm and the web speed of 3–5 m min−1. R2R deposition of the electron transport...

Solvent Systems for Industrial-Scale Processing of Spiro-OMeTAD Hole Transport Layer in Perovskite Solar Sells

Current laboratory-scale fabrication of perovskite solar cells involves the use of toxic solvents in the different fabrication steps. The aim of this research is to find a nontoxic alternative to chlorobenzene used for the deposition of hole transport material (HTM) spiro-OMeTAD. The initial selection of the solvents compatible with...

Higher-order multi-resolution topology optimization using the finite cell method

This article presents a detailed study on the potential and limitations of performing higher-order multi-resolution topology optimization with the finite cell method. To circumvent stiffness overestimation in high-contrast topologies, a length-scale is applied on the solution using filter methods. The relations between stiffness...