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de Vries, N.L. (author), Van Unen, Vincent (author), Ijsselsteijn, Marieke E. (author), Abdelaal, T.R.M. (author), Van Der Breggen, Ruud (author), Farina Sarasqueta, Arantza (author), Mahfouz, A.M.E.T.A. (author), Peeters, Koen C.M.J. (author), Höllt, T. (author), Lelieveldt, B.P.F. (author), Koning, Frits (author), De Miranda, Noel F.C.C. (author)Objective: A comprehensive understanding of anticancer immune responses is paramount for the optimal application and development of cancer immunotherapies. We unravelled local and systemic immune profiles in patients with colorectal cancer (CRC) by high-dimensional analysis to provide an unbiased characterisation of the immune contexture of...journal article 2019
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Redeker, Anke (author), Remmerswaal, Ester B.M. (author), van der Gracht, Esmé T.I. (author), Welten, Suzanne P.M. (author), Höllt, T. (author), Koning, Frits (author), Cicin-Sain, Luka (author), Nikolich-Žugich, Janko (author), ten Berge, Ineke J.M. (author), van Lier, René A. W. (author), van Unen, Vincent (author), Arens, Ramon (author)The relationship between human cytomegalovirus (HCMV) infections and accelerated immune senescence is controversial. Whereas some studies reported a CMV-associated impaired capacity to control heterologous infections at old age, other studies could not confirm this. We hypothesized that these discrepancies might relate to the variability in the...journal article 2018