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Antolović, I.M. (author), Burri, S (author), Hoebe, RA (author), Maruyama, Yuki (author), Bruschini, C (author), Charbon-Iwasaki-Charbon, E. (author)The paper presents a camera comprising 512 × 128 pixels capable of single-photon detection and gating with a maximum frame rate of 156 kfps. The photon capture is performed through a gated single-photon avalanche diode that generates a digital pulse upon photon detection and through a digital one-bit counter. Gray levels are obtained through...journal article 2016
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Zhao, Q. (author), Schelen, B. (author), Schouten, R. (author)We have built an all-solid-state camera that is directly modulated at the pixel level for frequency-domain fluorescence lifetime imaging microscopy (FLIM) measurements. This novel camera eliminates the need for an image intensifier through the use of an application-specific charge coupled device design in a frequency-domain FLIM system. The...journal article 2012
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Li, D.D.U. (author), Arlt, J. (author), Tyndall, D. (author), Walker, R. (author), Richardson, J. (author), Stoppa, D. (author), Charbon, E. (author), Henderson, R.K. (author)A high-speed and hardware-only algorithm using a center of mass method has been proposed for single-detector fluorescence lifetime sensing applications. This algorithm is now implemented on a field programmable gate array to provide fast lifetime estimates from a 32 × 32 low dark count 0.13 ?m complementary metaloxide-semiconductor single-photon...journal article 2011
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Zhao, Q. (author), Young, I.T. (author), De Jong, J.G.S. (author)We have constructed a mathematical model to analyze the photon efficiency of frequency-domain fluorescence lifetime imaging microscopy (FLIM). The power of the light source needed for illumination in a FLIM system and the signal-to-noise ratio of the detector have led us to a photon “budget.” These measures are relevant to many fluorescence...journal article 2011